Q5T2T1: MAGUK p55 subfamily member 7 (MPP7)

MAGUK p55 subfamily member 7 (MPP7) is a 576-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q5T2T1.

Gene
MPP7
Organism
Homo sapiens
Length
576 residues
Mean pLDDT
80.2
Model
AF-Q5T2T1-F1 v6
Model created
1 Aug 2025
PDB structures
2

Explore in 3D Color by confidence AlphaFold DB UniProt

Model confidence (pLDDT)

The mean pLDDT of this model is 80.2 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate39%
70 to 90Confident: backbone generally right42%
50 to 70Low: treat with caution7%
Below 50Very low: often disordered regions12%

What pLDDT means and how to read it

Function

Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact

Subunit structure

Heterodimer; able to heterodimerize via its C-terminal L27 domain with LIN7A, LIN7B and LIN7C. Forms a tripartite complex composed of DLG1, MPP7 and LIN7 (LIN7A or LIN7C). Interacts with DLG1 via its N-terminal L27 domain. Interacts with PALS1 and PATJ

Subcellular location

Membrane, Lateral cell membrane, Cell junction, tight junction, Cell junction, adherens junction, Cytoplasm, cell cortex, Cytoplasm

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
3O46X-ray1.3 ÅA=135-225
3LRAX-ray2.95 ÅA=9-120

More AlphaFold highlights

About this viewer

MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.