LLGL scribble cell polarity complex component 2 (LLGL2) is a 1020-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q6P1M3.
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The mean pLDDT of this model is 84.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 75% |
| 70 to 90 | Confident: backbone generally right | 6% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 15% |
What pLDDT means and how to read it
Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity
Interacts with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6. The complex is enhanced during mitosis. Interacts with DCAF1
Cytoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6N8R | X-ray | 1.91 Å | A=13-978 |
| 3WP0 | X-ray | 2.04 Å | B=640-654 |
| 6N8Q | X-ray | 2.2 Å | A=13-978 |
| 8R3X | X-ray | 2.59 Å | C/D=641-660 |
| 3WP1 | X-ray | 2.8 Å | A=646-662 |
| 9EJK | EM | 3.08 Å | A=13-978 |
| 6N8P | X-ray | 3.19 Å | A=13-978 |
| 9EJM | EM | 3.33 Å | A=13-978 |
| 9EJL | EM | 3.48 Å | A=13-978 |
| 6N8S | X-ray | 3.9 Å | A/D=13-978 |
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