Q71RC2: La-related protein 4 (LARP4)

La-related protein 4 (LARP4) is a 724-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q71RC2.

Gene
LARP4
Organism
Homo sapiens
Length
724 residues
Mean pLDDT
54.4
Model
AF-Q71RC2-F1 v6
Model created
1 Aug 2025
PDB structures
3

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Model confidence (pLDDT)

The mean pLDDT of this model is 54.4 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate19%
70 to 90Confident: backbone generally right6%
50 to 70Low: treat with caution9%
Below 50Very low: often disordered regions66%

What pLDDT means and how to read it

Function

RNA binding protein that binds to the poly-A tract of mRNA molecules (PubMed:21098120). Associates with the 40S ribosomal subunit and with polysomes (PubMed:21098120). Plays a role in the regulation of mRNA translation (PubMed:21098120). Essential for proper regulation of cell morphology and cytoskeletal organization (PubMed:21834987, PubMed:27615744)

Subunit structure

Interacts (via N-terminal region) with PABPC1 (PubMed:21098120, PubMed:27615744). Interacts with RACK1 (PubMed:21098120)

Subcellular location

Cytoplasm, Stress granule, Cytoplasm, cytosol

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
3PKNX-ray1.8 ÅB=13-26
2CQKNMRA=113-200
6I9BNMRA=111-287

More AlphaFold highlights

About this viewer

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