Tubulin beta chain (TUBB) is a 444-residue protein from Sus scrofa. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q767L7.
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The mean pLDDT of this model is 92.1 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 83% |
| 70 to 90 | Confident: backbone generally right | 12% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 2% |
What pLDDT means and how to read it
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:7225365). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (PubMed:7225365). Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:7225365)
Heterodimer of alpha and beta chains (PubMed:7225365). A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules…
Cytoplasm, cytoskeleton
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9M1J | EM | 2.14 Å | b=1-431 |
| 9M1M | EM | 2.21 Å | b=1-444 |
| 9M1N | EM | 2.24 Å | b=1-444 |
| 9M1K | EM | 2.45 Å | b=1-444 |
| 9M1I | EM | 2.48 Å | b=1-444 |
| 9M1L | EM | 2.55 Å | b=1-444 |
| 8YY3 | EM | 3.24 Å | B=1-444 |
| 8YY2 | EM | 3.6 Å | B=1-444 |
| 8YY5 | EM | 3.99 Å | B=1-444 |
| 8YY4 | EM | 4.02 Å | B=1-444 |
| 9UMU | EM | 4.4 Å | B=1-444 |
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