Chromo domain-containing protein rhino (rhi) is a 418-residue protein from Drosophila melanogaster. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q7JXA8.
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The mean pLDDT of this model is 61.2 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 23% |
| 70 to 90 | Confident: backbone generally right | 10% |
| 50 to 70 | Low: treat with caution | 21% |
| Below 50 | Very low: often disordered regions | 47% |
What pLDDT means and how to read it
Involved in piRNA (piwi-interacting RNA)-mediated transposon repression (PubMed:19732946, PubMed:36193674). May be involved in formation of the perinuclear nuage, a subcellular structure implicated in RNA processing that may be involved in transposon RNA surveillance and silencing (PubMed:19732946, PubMed:36193674). Required for ping-pong amplification during piRNA biogenesis, probably by promoting transcription of piRNA precursors (PubMed:19732946, PubMed:25085419, PubMed:36193674). As part of the Rhino-Deadlock-Cutoff (RDC) Complex associates with, and drives non-canonical transcription of germline specific dual-strand piRNA clusters 80F, 38C and 42AB, but not single-stranded piRNA…
Homodimer in solution (PubMed:25085419, PubMed:25613572). Dimerization is essential for chromatin binding (PubMed:25613572). Component of the Rhino-Deadlock-Cutoff (RDC) complex, composed of rhi/rhino, del/deadlock and cuff/cutoff (PubMed:24906153). Interacts (via C-terminus) with del/deadlock (via N-terminus); this interaction is direct (PubMed:24906153, PubMed:29858487). Two copies of…
Nucleus, Chromosome
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4QUC | X-ray | 1.5 Å | A=19-85 |
| 4U68 | X-ray | 1.8 Å | A/B/C=20-90 |
| 5XYV | X-ray | 2.1 Å | A/B=353-418 |
| 4QUF | X-ray | 2.5 Å | A/B/C/D/E/F=19-85 |
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