Zinc finger FYVE domain-containing protein 16 (ZFYVE16) is a 1539-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q7Z3T8.
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The mean pLDDT of this model is 54.6 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 23% |
| 70 to 90 | Confident: backbone generally right | 16% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 58% |
What pLDDT means and how to read it
May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes
Interacts (via C-terminus) with TOM1 (via C-terminus); interaction is required to target TOM1 to endosomes (PubMed:14613930). Does not interact with TOM1L1 or TOM1L2 (PubMed:14613930)
Cytoplasm, Early endosome membrane
Compare the prediction with experimentally determined structures of the same protein:
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