Dendrin (Ddn) is a 710-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q80TS7.
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The mean pLDDT of this model is 45.2 (very low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 0% |
| 70 to 90 | Confident: backbone generally right | 8% |
| 50 to 70 | Low: treat with caution | 14% |
| Below 50 | Very low: often disordered regions | 78% |
What pLDDT means and how to read it
Promotes apoptosis of kidney glomerular podocytes. Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein
Forms a ternary complex with MAGI2 and SH3KBP1; recruits DDN to the cytoplasm (By similarity). Interacts with MAGI1 (By similarity). Interacts with ACTN1 and may interact with WWC1 (By similarity). Interacts with the podocyte slit diaphragm proteins CD2AP, NPHS1 and NPHS2; the interaction with CD2AP and NPHS1 is direct
Cell projection, dendritic spine membrane, Cytoplasm, Endoplasmic reticulum membrane, Perikaryon, Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7BQG | X-ray | 1.55 Å | A=225-235 |
| 6JJZ | X-ray | 1.65 Å | C/D=222-235 |
| 6JK1 | X-ray | 2.0 Å | A/B=222-241 |
| 6KKG | X-ray | 2.15 Å | C/D=222-241 |
| 6J69 | X-ray | 2.75 Å | B=222-246 |
| 6JK0 | X-ray | 3.1 Å | A=222-241 |
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