Structure of KIBRA and Dendrin Complex. Determined by X-ray diffraction at 2.75 Å resolution. Released 20 Mar 2019.
Explore 6J69 in 3D Show helices and sheets RCSB PDB PDBe
6J69 contains 5 α-helices and 7 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 6-9 | 4 | |
| β-strand | 12-16 | 5 | 1 |
| β-strand | 22-26 | 5 | 1 |
| β-strand | 31-33 | 3 | 1 |
| α-helix | 39-42 | 4 | |
| α-helix | 54-56 | 3 | |
| β-strand | 59-64 | 6 | 2 |
| β-strand | 68-73 | 6 | 2 |
| β-strand | 78-80 | 3 | 2 |
| α-helix | 84-123 | 40 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 224-227 | 4 | |
| β-strand | 238 | 1 | 1 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Protein KIBRA | A | protein | 134 | Mus musculus | Q5SXA9 (AlphaFold model) |
| Peptide from Dendrin | B | protein | 25 | Mus musculus | Q80TS7 (AlphaFold model) |
>6J69_1 Protein KIBRA (chains A) GPGSEFELPLPEGWEEARDFDGKVYYIDHRNRTTSWIDPRDRYTKPLTFADCISDELPLG WEEAYDPQVGDYFIDHNTKTTQIEDPRVQWRREQEHMLKDYLVVAQEALSAQKEIYQVKQ QRLELAQQEYQQLH
>6J69_2 Peptide from Dendrin (chains B) DRPPPYVAPPSYEGPHRTLGTKRGP
Kibra Modulates Learning and Memory via Binding to Dendrin. Ji, Z., Li, H., Yang, Z. et al. Cell Rep (2019) 26:2064-2077.e7. DOI 10.1016/j.celrep.2019.01.097 · PubMed
Other PDB entries of the same protein (UniProt Q5SXA9 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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