Nuclear pore complex protein Nup93 (NUP93) is a 819-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q8N1F7.
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The mean pLDDT of this model is 79.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 21% |
| 70 to 90 | Confident: backbone generally right | 60% |
| 50 to 70 | Low: treat with caution | 13% |
| Below 50 | Very low: often disordered regions | 6% |
What pLDDT means and how to read it
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance (PubMed:9348540). May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling (PubMed:26878725)
Part of the nuclear pore complex (NPC) (PubMed:15229283, PubMed:15703211, PubMed:9348540). Component of the p62 complex, a complex composed of NUP62 and NUP54 (PubMed:9348540). Forms a complex with NUP35, NUP155, NUP205 and lamin B; the interaction with NUP35 is direct (PubMed:15703211). Does not interact with TPR (PubMed:12802065, PubMed:15229283). Interacts with SMAD4 and IPO7; translocates…
Nucleus membrane, Nucleus, nuclear pore complex, Nucleus envelope
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7MW0 | X-ray | 2.0 Å | A=174-819 |
| 7MW1 | X-ray | 3.4 Å | A/B=174-819 |
| 7R5K | EM | 12.0 Å | A0/A1/A2/A3/A4/A5/A6=1-819 |
| 5IJN | EM | 21.4 Å | C/I/O/U=1-819 |
| 5IJO | EM | 21.4 Å | C/I/O/U=1-819 |
| 7PER | EM | 35.0 Å | C/I/O/U=1-819 |
| 7R5J | EM | 50.0 Å | A0/A1/A2/A3/A4/A5/A6=1-819 |
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