Nuclear pore complex protein Nup133 (NUP133) is a 1156-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q8WUM0.
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The mean pLDDT of this model is 78.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 32% |
| 70 to 90 | Confident: backbone generally right | 49% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 13% |
What pLDDT means and how to read it
Involved in poly(A)+ RNA transport. Involved in nephrogenesis (PubMed:30179222)
Forms part of the Nup160 subcomplex in the nuclear pore which is composed of NUP160, NUP133, NUP107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and NUP153 to the nucleus
Nucleus, nuclear pore complex, Chromosome, centromere, kinetochore
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1XKS | X-ray | 2.35 Å | A=67-514 |
| 3CQC | X-ray | 2.53 Å | B=935-1156 |
| 3CQG | X-ray | 3.0 Å | B=934-1156 |
| 3I4R | X-ray | 3.53 Å | B=517-1156 |
| 7R5K | EM | 12.0 Å | K0/K1/K2/K3=1-1156 |
| 5A9Q | EM | 23.0 Å | 3/C/L/U=1-1156 |
| 7PEQ | EM | 35.0 Å | AC/BC/CC/DC=1-1156 |
| 7R5J | EM | 50.0 Å | K0/K1/K2/K3=1-1156 |
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