Q922G7: Tektin-2 (Tekt2)

Tektin-2 (Tekt2) is a 430-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q922G7.

Gene
Tekt2
Organism
Mus musculus
Length
430 residues
Mean pLDDT
90.6
Model
AF-Q922G7-F1 v6
Model created
1 Aug 2025
PDB structures
4

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Model confidence (pLDDT)

The mean pLDDT of this model is 90.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate84%
70 to 90Confident: backbone generally right6%
50 to 70Low: treat with caution2%
Below 50Very low: often disordered regions7%

What pLDDT means and how to read it

Function

Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme (PubMed:15340058, PubMed:37295417, PubMed:37865089, PubMed:37989994). Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia (PubMed:15340058). Forms filamentous polymers in the walls of ciliary and flagellar microtubules (PubMed:15340058)

Subunit structure

Microtubule inner protein component of sperm flagellar doublet microtubules (PubMed:37295417, PubMed:37865089, PubMed:37989994). May interact with CCDC172 (PubMed:24394471)

Subcellular location

Cytoplasm, cytoskeleton, cilium axoneme, Cytoplasm, cytoskeleton, flagellum axoneme, Cytoplasm, cytoskeleton, microtubule organizing center

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8IYJEM3.5 ÅB0/B1/B2/B3/B4/B5/R0/R1/R2/R3/R4/R5=1-430
8I7OEM4.5 ÅB2/B3/B7/B8=1-430
8I7REM6.5 ÅB1/B2/B3/B4/B5/B6/B7/B8/B9=1-430
8TO0EM7.7 Åb/e/f/g/h/i/j/k/l/m=1-430

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