Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (PPWD1) is a 646-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q96BP3.
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The mean pLDDT of this model is 85.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 72% |
| 70 to 90 | Confident: backbone generally right | 11% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 10% |
What pLDDT means and how to read it
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357). May be involved in pre-mRNA splicing (PubMed:11991638)
Identified in the spliceosome C complex
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 2A2N | X-ray | 1.65 Å | A/B/C=473-646 |
| 9FMD | EM | 3.3 Å | w=1-646 |
| 8I0W | EM | 3.4 Å | 3=1-646 |
| 5YZG | EM | 4.1 Å | 2=1-646 |
| 7A5P | EM | 5.0 Å | z=1-646 |
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