Q99176: Protein SRN2 (SRN2)

Protein SRN2 (SRN2) is a 213-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q99176.

Gene
SRN2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
213 residues
Mean pLDDT
83.4
Model
AF-Q99176-F1 v6
Model created
1 Aug 2025
PDB structures
3

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Model confidence (pLDDT)

The mean pLDDT of this model is 83.4 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate51%
70 to 90Confident: backbone generally right27%
50 to 70Low: treat with caution15%
Below 50Very low: often disordered regions7%

What pLDDT means and how to read it

Function

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for normal endocytic and biosynthetic traffic to the yeast vacuole

Subunit structure

Component of the ESCRT-I complex (endosomal sorting complex required for transport I) which consists of STP22, VPS28, SRN2 and MVB12 in a 1:1:1:1 stoichiometry. Interacts with STP22 and MVB12

Subcellular location

Cytoplasm, Endosome, Late endosome membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
2P22X-ray2.7 ÅC=22-213
2F66X-ray2.8 ÅC/F=132-213
2CAZX-ray3.6 ÅC/F=130-213

More AlphaFold highlights

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