Myosin-7 (MYH7) is a 1935-residue protein from Bos taurus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9BE39.
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The mean pLDDT of this model is 74.1 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 12% |
| 70 to 90 | Confident: backbone generally right | 52% |
| 50 to 70 | Low: treat with caution | 31% |
| Below 50 | Very low: often disordered regions | 5% |
What pLDDT means and how to read it
Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle
Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Interacts with ECPAS. Interacts (via C-terminus) with LRRC39
Cytoplasm, myofibril, Cytoplasm, myofibril, sarcomere
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8QYR | X-ray | 1.8 Å | B=1-781 |
| 8QYU | X-ray | 1.96 Å | A/B=1-810 |
| 6FSA | X-ray | 2.33 Å | A/B=1-1935 |
| 9F6C | X-ray | 2.33 Å | A/B=1-782 |
| 5N69 | X-ray | 2.45 Å | A/B=1-828 |
| 8QYQ | X-ray | 2.61 Å | A/B=1-807 |
| 8QYP | X-ray | 2.76 Å | A=1-780 |
| 5N6A | X-ray | 3.1 Å | A=1-828 |
| 6X5Z | EM | 4.24 Å | D/G/J=1-850 |
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