Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C) is a 147-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9BXW4.
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The mean pLDDT of this model is 79.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 40% |
| 70 to 90 | Confident: backbone generally right | 38% |
| 50 to 70 | Low: treat with caution | 11% |
| Below 50 | Very low: often disordered regions | 12% |
What pLDDT means and how to read it
Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2 (PubMed:23022382). Recruits all ATG8 family members to infecting bacteria such as S.typhimurium (PubMed:23022382). May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins (PubMed:28404643)
3 different light chains, LC1 (a cleavage product of MAP1B), LC2 (a cleavage product of MAP1A) and LC3 (produced by one of the MAP1LC3 genes), can associate with the MAP1A or MAP1B heavy chains (By similarity). Interacts with TP53INP1 and TP53INP2 (PubMed:22470510). Interacts with CALCOCO2 (PubMed:23022382). Interacts with TECPR2 (PubMed:20562859). Interacts with TBC1D5 (PubMed:22354992). Found…
Cytoplasmic vesicle, autophagosome membrane, Endomembrane system, Cytoplasm, cytoskeleton
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 3WAM | X-ray | 1.75 Å | A=8-125 |
| 5DPW | X-ray | 2.19 Å | A/C/E/G/I/K/M/O=8-125 |
| 3VVW | X-ray | 2.5 Å | B=1-126 |
| 3WAP | X-ray | 3.1 Å | A=8-125 |
| 2NCN | NMR | A=1-126 |
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