Q9D0L1: Zinc finger BED domain-containing protein 3 (Zbed3)

Zinc finger BED domain-containing protein 3 (Zbed3) is a 228-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9D0L1.

Gene
Zbed3
Organism
Mus musculus
Length
228 residues
Mean pLDDT
73.8
Model
AF-Q9D0L1-F1 v6
Model created
1 Aug 2025
PDB structures
4

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Model confidence (pLDDT)

The mean pLDDT of this model is 73.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate35%
70 to 90Confident: backbone generally right19%
50 to 70Low: treat with caution27%
Below 50Very low: often disordered regions18%

What pLDDT means and how to read it

Function

Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin (PubMed:19141611). Involved in transcription activation of Wnt target gene expression (PubMed:19141611). Plays a role in symmetric division of blastomeres in the early stages of embryogenesis via regulation of mitotic spindle central positioning and organization of the F-actin filament network (PubMed:28992324). Component of cytoplasmic lattices, which consist in fibrous structures found in the cytoplasm of oocytes and preimplantation embryos: they are required to store maternal proteins critical for embryonic development, such as ribosomal proteins,…

Subunit structure

Component of cytoplasmic lattices, at least composed of PADI6, NLRP4F, NLRP5, NLRP14, TLE6, KHDC3, OOEP and ZBED3 (PubMed:28992324, PubMed:31575650, PubMed:41845018, PubMed:41917274, PubMed:41986725, PubMed:41118754). Cytoplasmic lattices form a filamentous architecture; the external framework is built from PADI6 decamers and the subcortical maternal complexes (SCMC) (PubMed:41845018,…

Subcellular location

Cytoplasm, Membrane, Secreted

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
9L4JEM3.0 ÅE=34-89
9XRLEM3.74 Å1/3/9=34-89
9SFPEM4.2 Åe=32-88
9W2MEM4.2 ÅR/r=34-87

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