1CQ0: Protein

Solution structure of a human hypocretin-2/OREXIN-b'solution structure of a human hypocretin-2/OREXIN-B '. Determined by solution NMR. Released 10 Jan 2000.

Method: Solution NMR
Organism: Homo sapiens
Chains: 1
Atoms: 203
Mol. weight: 2.89 kDa
Released: 10 Jan 2000

Explore 1CQ0 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1CQ0 contains 3 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 3 helices, 0 β-strands

Element	Residues	Length
α-helix	7-11	5
α-helix	12-17	6
α-helix	22-26	5

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Protein (new hypothalamic neuropeptide/orexin-B28)	A	protein	28	Homo sapiens	O43612 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>1CQ0_1 PROTEIN (NEW HYPOTHALAMIC NEUROPEPTIDE/OREXIN-B28) (chains A)
FSGPPGLQGRLQRLLQASGNHAAGILTM

Primary citation

Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B. Lee, J.H., Bang, E., Chae, K.J. et al. Eur J Biochem (1999) 266:831-839. DOI 10.1046/j.1432-1327.1999.00911.x · PubMed

Other PDB entries of the same protein (UniProt O43612 (AlphaFold model), which also has an AlphaFold model), best resolution first:

1UVQ 1.8 Å, Crystal structure of HLA-DQ0602 in complex with a hypocretin peptide
7L1U 3.2 Å, Orexin Receptor 2 (OX2R) in Complex with G Protein and Natural Peptide-Agonist Orexin B…
1R02 Solution structure of Human Orexin-A:Regulator of Appetite and Wakefulness
1WSO The solution structures of human Orexin-A

Browse structure collections

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