The solution structures of human Orexin-A. Determined by solution NMR. Released 30 Nov 2004.
Explore 1WSO in 3D Show helices and sheets RCSB PDB PDBe
1WSO contains 4 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 2-4 | 3 | |
| α-helix | 6-9 | 4 | |
| α-helix | 16-23 | 8 | |
| α-helix | 25-32 | 8 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Orexin-A | A | protein | 34 | Homo sapiens | O43612 (AlphaFold model) |
>1WSO_1 Orexin-A (chains A) QPLPDCCRQKTCSCRLYELLHGAGNHAAGILTLX
Orexin-A is composed of a highly conserved C-terminal and a specific, hydrophilic N-terminal region, revealing the structural basis of specific recognition by the orexin-1 receptor. Takai, T., Takaya, T., Nakano, M. et al. J Pept Sci (2006) 12:443-454. DOI 10.1002/psc.747 · PubMed
Other PDB entries of the same protein (UniProt O43612 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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