1E07: Carcinoembryonic antigen

Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data. Determined by solution scattering. Released 4 Jul 2000.

Method

Solution scattering

Organism

HOMO SAPIENS

Chains

1

Atoms

642

Mol. weight

70.62 kDa

Released

4 Jul 2000

Explore 1E07 in 3D Show helices and sheets RCSB PDB PDBe

Molecules and chains

>1E07_1 CARCINOEMBRYONIC ANTIGEN (chains A)
KLTIESTPFNVAEGKEVLLLVHNLPQHLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPA
YSGREIIYPNASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRVYPELPKPSISSNNS
KPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYK
CETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAASNPPAQYSWFVN
GTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNP
VEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECG
IQNELSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGN
IQQHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVE
DKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQ
NSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQ
QHTQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSA

Primary citation

Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23. Boehm, M.K., Perkins, S.J. FEBS Lett (2000) 475:11-16. DOI 10.1016/s0014-5793(00)01612-4 · PubMed

Related structures

Other PDB entries of the same protein (UniProt P06731 (AlphaFold model), which also has an AlphaFold model), best resolution first:

• 2QSQ 1.95 Å, Crystal structure of the N-terminal domain of carcinoembryonic antigen (CEA)
• 9U93 2.4 Å, Cryo-EM structure of Fusobacterium nucleatum CbpF in complex with human CEACAM5
• 2QST 2.9 Å, Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic…
• 8BW0 3.11 Å, Structure of CEACAM5 A3-B3 domain in Complex with Tusamitamab Fab
• 2VER Structural model for the complex between the Dr adhesins and carcinoembryonic antigen…

Browse structure collections

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