1FGD: Thrombomodulin
Epidermal growth factor (EGF) subdomain of human thrombomodulin (NMR, 11 structures). Determined by solution NMR. Released 20 Jun 1996.
- Method
- Solution NMR
- Organism
- Homo sapiens
- Chains
- 1
- Atoms
- 140
- Mol. weight
- 2.02 kDa
- Released
- 20 Jun 1996
Explore 1FGD in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
1FGD contains 0 α-helices and 2 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain A: 0 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 415-416 | 2 | 1 |
| β-strand | 420-421 | 2 | 1 |
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Thrombomodulin | A | protein | 18 | Homo sapiens | P07204 (AlphaFold model) |
Sequence of entity 1 (A), FASTA
>1FGD_1 THROMBOMODULIN (chains A)
CPEGYILDDGFICTDIDE
Primary citation
Structural resiliency of an EGF-like subdomain bound to its target protein, thrombin. Hrabal, R., Komives, E.A., Ni, F. Protein Sci (1996) 5:195-203. PubMed
Other PDB entries of the same protein (UniProt P07204 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 1DX5 2.3 Å, Crystal structure of the thrombin-thrombomodulin complex
- 5TO3 2.34 Å, Crystal structure of thrombin mutant W215A/E217A fused to EGF456 of thrombomodulin via a…
- 3GIS 2.4 Å, Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin
- 1HLT 3.0 Å, The structure of a nonadecapeptide of the fifth egf domain of thrombomodulin complexed…
- 7T4R 3.3 Å, CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with THBD and…
- 1ADX Fifth egf-like domain of thrombomodulin (TMEGF5), NMR, 14 structures
- 1DQB NMR structure of thrombomodulin EGF(4-5)
- 1EGT Thrombin-bound structure of an egf subdomain from human thrombomodulin determined by…
- 1FGE Epidermal growth factor (EGF) subdomain of human thrombomodulin (NMR, 14 structures)
- 1TMR The structure of a 19 residue fragment from the C-loop of the fourth epidermal growth…
- 1ZAQ Fourth egf-like domain of thrombomodulin, NMR, 12 structures
- 2ADX Fifth egf-like domain of thrombomodulin (TMEGF5), NMR, minimized average structure
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