1IQ5: Calmodulin

Calmodulin/nematode CA2+/Calmodulin dependent kinase kinase fragment. Determined by X-ray diffraction at 1.8 Å resolution. Released 26 Sept 2001.

Method: X-ray diffraction
Resolution: 1.8 Å
Organism: Xenopus laevis
Chains: 2
Atoms: 1,396
Mol. weight: 20.21 kDa
Ligands: CA
Released: 26 Sept 2001

Explore 1IQ5 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1IQ5 contains 9 α-helices and 4 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 8 helices, 4 β-strands

Element	Residues	Length	Sheet
α-helix	6-19	14
β-strand	26-27	2	1
α-helix	29-38	10
α-helix	45-53	9
β-strand	63-64	2	1
α-helix	65-75	11
α-helix	83-92	10
β-strand	99-100	2	2
α-helix	102-111	10
α-helix	118-128	11
β-strand	136-137	2	2
α-helix	138-145	8

Chain B: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	337-349	13

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Calmodulin	A	protein	149	Xenopus laevis	P0DP33 (AlphaFold model)
CA2+/CALMODULIN dependent kinase kinase	B	protein	27		Q3Y416 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>1IQ5_1 CALMODULIN (chains A)
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
EVDEMIREADIDGDGQVNYEEFVQMMTAK

Sequence of entity 2 (B), FASTA

>1IQ5_2 CA2+/CALMODULIN DEPENDENT KINASE KINASE (chains B)
VRVIPRLDTLILVKAMGHRKRFGNPFR

Ligands and cofactors

ID	Name	Formula	Copies
CA	Calcium ion	Ca	4

Primary citation

Target-induced conformational adaptation of calmodulin revealed by the crystal structure of a complex with nematode Ca(2+)/calmodulin-dependent kinase kinase peptide. Kurokawa, H., Osawa, M., Kurihara, H. et al. J Mol Biol (2001) 312:59-68. DOI 10.1006/jmbi.2001.4822 · PubMed

Other PDB entries of the same protein (UniProt P0DP33 (AlphaFold model), which also has an AlphaFold model), best resolution first:

2COL 2.2 Å, Crystal structure analysis of CyaA/C-Cam with Pyrophosphate
4R8G 3.5 Å, Crystal Structure of Myosin-1c tail in complex with Calmodulin
1Y0V 3.6 Å, Crystal structure of anthrax edema factor (EF) in complex with calmodulin and…
1CFC Calcium-free calmodulin
1CFD Calcium-free calmodulin
1CFF NMR solution structure of a complex of calmodulin with a binding peptide of the CA2+-pump
1CKK Calmodulin/rat CA2+/CALMODULIN dependent protein kinase fragment
1DMO Calmodulin, NMR, 30 structures
1F70 Refined solution structure of calmodulin N-terminal domain
1F71 Refined solution structure of calmodulin C-terminal domain
1MUX Solution NMR structure of calmodulin/w-7 complex: the basis of diversity in molecular…
1NWD Solution Structure of Ca2+/Calmodulin bound to the C-terminal Domain of Petunia…

Browse structure collections

About this viewer

MolViewer shows 1IQ5 directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.