1L0H: Butyryl-ACP from e.coli

Crystal structure of butyryl-ACP from e.coli. Determined by X-ray diffraction at 2.0 Å resolution. Released 11 Feb 2003.

Method: X-ray diffraction
Resolution: 2.0 Å
Organism: Escherichia coli
Chains: 1
Atoms: 651
Mol. weight: 8.78 kDa
Ligands: ZN
Released: 11 Feb 2003

Explore 1L0H in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1L0H contains 5 α-helices and 2 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 5 helices, 2 β-strands

Element	Residues	Length	Sheet
α-helix	3-15	13
α-helix	19-21	3
β-strand	27	1	1
α-helix	36-49	14
α-helix	56-59	4
β-strand	64	1	1
α-helix	65-74	10

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Acyl carrier protein	A	protein	78	Escherichia coli	P0A6A8 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>1L0H_1 ACYL CARRIER PROTEIN (chains A)
MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEA
EKITTVQAAIDYINGHQA

Ligands and cofactors

ID	Name	Formula	Copies
ZN	Zinc ion	Zn	2

Primary citation

X-ray crystallographic studies on butyryl-ACP reveal flexibility of the structure around a putative acyl chain binding site. Roujeinikova, A., Baldock, C., Simon, W.J. et al. Structure (2002) 10:825-835. DOI 10.1016/S0969-2126(02)00775-X · PubMed

Other PDB entries of the same protein (UniProt P0A6A8 (AlphaFold model), which also has an AlphaFold model), best resolution first:

1T8K 1.1 Å, Crystal Structure of apo acyl carrier protein from E. coli
1L0I 1.2 Å, Crystal structure of butyryl-ACP I62M mutant
9KA6 1.47 Å, Crystal structure of beta-ketoacyl-ACP synthase FabH C112Q in complex with acyl-ACP from…
2FAE 1.55 Å, Crystal structure of E. coli decanoyl-ACP
6OKC 1.55 Å, Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and…
6UXE 1.57 Å, Structure of the human mitochondrial desulfurase complex Nfs1-ISCU2(M140I)-ISD11 with…
2FAD 1.6 Å, Crystal structure of E. coli heptanoyl-ACP
7SQI 1.7 Å, Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and…
2FAC 1.76 Å, Crystal structure of E. coli hexanoyl-ACP
6W1D 1.79 Å, Structure of human mitochondrial complex Nfs1-ISCU2 (WT)-ISD11 with E.coli ACP1 at 1.8 A…
6U0J 1.9 Å, Crosslinked Crystal Structure of Malonyl-CoA Acyl Carrier Protein Transacylase, FabD,…
6WIH 1.9 Å, N-terminal mutation of ISCU2 (L35H36) traps Nfs1 Cys loop in the active site of ISCU2…

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