1SHT: Anthrax toxin receptor 2

Crystal Structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor. Determined by X-ray diffraction at 1.81 Å resolution. Released 13 Apr 2004.

Method
X-ray diffraction
Resolution
1.81 Å
Organism
Homo sapiens
Chains
1
Atoms
1,570
Mol. weight
19.88 kDa
Ligands
MG
Released
13 Apr 2004

Explore 1SHT in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1SHT contains 9 α-helices and 6 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain X: 9 helices, 6 β-strands

ElementResiduesLengthSheet
β-strand43-5081
α-helix53-586
α-helix59-7214
β-strand79-8571
β-strand89-9681
α-helix99-11012
α-helix120-13415
α-helix136-1383
β-strand140-14781
α-helix155-16814
β-strand172-17761
α-helix183-1897
α-helix193-1953
β-strand196-19831
α-helix205-21410

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Anthrax toxin receptor 2Xprotein181Homo sapiensP58335 (AlphaFold model)
Sequence of entity 1 (X), FASTA
>1SHT_1 Anthrax toxin receptor 2 (chains X)
GSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLT
GDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVP
SYAEKEAKISRSLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQ
S

Ligands and cofactors

IDNameFormulaCopies
MGMagnesium ionMg1

Water and common crystallization additives (ACT) are not listed.

Primary citation

Crystal Structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor. Lacy, D.B., Wigelsworth, D.J., Scobie, H.M. et al. Proc Natl Acad Sci U S A (2004) 101:6367-6372. DOI 10.1073/pnas.0401506101 · PubMed

Other PDB entries of the same protein (UniProt P58335 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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