Crystal structure of the Rattus norvegicus voltage gated calcium channel beta subunit isoform 2a. Determined by X-ray diffraction at 1.97 Å resolution. Released 15 Jun 2004.
Explore 1T0H in 3D Show helices and sheets RCSB PDB PDBe
1T0H contains 15 α-helices and 13 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 43-55 | 13 | |
| α-helix | 59-60 | 2 | |
| β-strand | 62-66 | 5 | 1 |
| β-strand | 70 | 1 | 2 |
| α-helix | 74-76 | 3 | |
| β-strand | 84 | 1 | 1 |
| β-strand | 87 | 1 | 2 |
| β-strand | 92-98 | 7 | 1 |
| β-strand | 103-108 | 6 | 1 |
| β-strand | 116-119 | 4 | 1 |
| α-helix | 120 | 1 | |
| α-helix | 121-134 | 14 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 220-223 | 4 | 1 |
| α-helix | 227-228 | 2 | |
| β-strand | 229-232 | 4 | 3 |
| α-helix | 240-256 | 17 | |
| β-strand | 261-266 | 6 | 3 |
| α-helix | 270-272 | 3 | |
| α-helix | 286-288 | 3 | |
| α-helix | 296-310 | 15 | |
| β-strand | 315-320 | 6 | 3 |
| α-helix | 326-328 | 3 | |
| β-strand | 337-341 | 5 | 3 |
| α-helix | 346-355 | 10 | |
| α-helix | 364-375 | 12 | |
| α-helix | 379-382 | 4 | |
| β-strand | 385-387 | 3 | 3 |
| α-helix | 392-410 | 19 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Voltage-gated calcium channel subunit BETA2A | A | protein | 132 | Rattus norvegicus | Q8VGC3 (AlphaFold model) |
| Voltage-gated calcium channel subunit BETA2A | B | protein | 224 | Rattus norvegicus | Q8VGC3 (AlphaFold model) |
>1T0H_1 VOLTAGE-GATED CALCIUM CHANNEL SUBUNIT BETA2A (chains A) GHMGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVRYSAA QEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ RAKQGKFYSSKS
>1T0H_2 VOLTAGE-GATED CALCIUM CHANNEL SUBUNIT BETA2A (chains B) MSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRI SITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDAD TINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPQE SFDVILDENQLEDACEHLADYLEAYWKATHPPSSNLPNPLLSRT
Structure of a complex between a voltage-gated calcium channel beta-subunit and an alpha-subunit domain. Van Petegem, F., Clark, K.A., Chatelain, F.C. et al. Nature (2004) 429:671-675. DOI 10.1038/nature02588 · PubMed
Other PDB entries of the same protein (UniProt Q8VGC3 (AlphaFold model), which also has an AlphaFold model), best resolution first:
MolViewer shows 1T0H directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.