1YTF: Yeast tfiia/tbp/dna complex

Yeast tfiia/tbp/dna complex. Determined by X-ray diffraction at 2.5 Å resolution. Released 20 Jun 1996.

Method
X-ray diffraction
Resolution
2.5 Å
Organism
Saccharomyces cerevisiae
Chains
6
Atoms
3,605
Mol. weight
58.31 kDa
Released
20 Jun 1996

Explore 1YTF in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1YTF contains 10 α-helices and 18 β-strands across 4 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 5 helices, 12 β-strands

ElementResiduesLengthSheet
α-helix651
β-strand66-75101
α-helix82-887
β-strand92-9431
β-strand102-10761
β-strand110-11561
β-strand120-12671
α-helix129-14618
β-strand153-165131
β-strand17012
α-helix172-1787
β-strand183-18421
β-strand193-19751
β-strand202-20651
β-strand211-21771
α-helix220-23617
β-strand23812
Chain B: 2 helices, 0 β-strands
ElementResiduesLengthSheet
α-helix4-2724
α-helix32-4615
Chain C: 0 helices, 3 β-strands
ElementResiduesLengthSheet
β-strand243-254121
β-strand257-269131
β-strand272-284131
Chain D: 3 helices, 3 β-strands
ElementResiduesLengthSheet
α-helix9-124
α-helix14-2815
α-helix36-5419
β-strand59-72141
β-strand75-87131
β-strand105-117131

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
DNA (5'-d(*tp*gp*tp*ap*tp*gp*tp*ap*tp*ap*tp*ap*ap*ap*ap*c)-3')EDNA16
DNA (5'-d(*gp*tp*tp*tp*tp*ap*tp*ap*tp*ap*cp*ap*tp*ap*cp*a)-3')FDNA16
Protein (tata binding protein (tbp))Aprotein180Saccharomyces cerevisiaeP13393 (AlphaFold model)
Protein (transcription factor iia - TOA1N subunit)Bprotein53Saccharomyces cerevisiaeP32773 (AlphaFold model)
Protein (transcription factor iia - TOA1C subunit)Cprotein79Saccharomyces cerevisiaeP32773 (AlphaFold model)
Protein (transcription factor iia - TOA2 subunit)Dprotein121Saccharomyces cerevisiaeP32774 (AlphaFold model)
Sequence of entity 1 (E), FASTA
>1YTF_1 DNA (5'-D(*TP*GP*TP*AP*TP*GP*TP*AP*TP*AP*TP*AP*AP*AP*AP*C)-3') (chains E)
TGTATGTATATAAAAC
Sequence of entity 2 (F), FASTA
>1YTF_2 DNA (5'-D(*GP*TP*TP*TP*TP*AP*TP*AP*TP*AP*CP*AP*TP*AP*CP*A)-3') (chains F)
GTTTTATATACATACA
Sequence of entity 3 (A), FASTA
>1YTF_3 PROTEIN (TATA BINDING PROTEIN (TBP)) (chains A)
SGIVPTLQNIVATVTLGCRLDLKTVALHARNAEYNPKRFAAVIMRIREPKTTALIFASGK
MVVTGAKSEDDSKLASRKYARIIQKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHG
TFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKM
Sequence of entity 4 (B), FASTA
>1YTF_4 PROTEIN (TRANSCRIPTION FACTOR IIA - TOA1N SUBUNIT) (chains B)
SNAEASRVYEIIVESVVNEVREDFENAGIDEQTLQDLKNIWQKKLTETKVTTF
Sequence of entity 5 (C), FASTA
>1YTF_5 PROTEIN (TRANSCRIPTION FACTOR IIA - TOA1C SUBUNIT) (chains C)
GSSALLDTDEVGSELDDSDDDYLISEGEEDGPDENLMLCLYDKVTRTKARWKCSLKDGVV
TINRNDYTFQKAQVEAEWV
Sequence of entity 6 (D), FASTA
>1YTF_6 PROTEIN (TRANSCRIPTION FACTOR IIA - TOA2 SUBUNIT) (chains D)
AVPGYYELYRRSTIGNSLVDALDTLISDGRIEASLAMRVLETFDKVVAETLKDNTQSKLT
VKGNLDTYGFCDDVWTFIVKNCQVTVEDSHRDASQNGSGDSQSVISVDKLRIVACNSKKS
E

Primary citation

Crystal structure of a yeast TFIIA/TBP/DNA complex. Tan, S., Hunziker, Y., Sargent, D.F. et al. Nature (1996) 381:127-134. DOI 10.1038/381127a0 · PubMed

Other PDB entries of the same protein (UniProt P13393 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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