2KEF: Human hepcidin at 325K

Solution NMR structures of human hepcidin at 325K. Determined by solution NMR. Released 23 Jun 2009.

Method: Solution NMR
Organism: Homo sapiens
Chains: 1
Atoms: 186
Mol. weight: 2.8 kDa
Released: 23 Jun 2009

Explore 2KEF in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2KEF contains 0 α-helices and 2 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 0 helices, 2 β-strands

Element	Residues	Length	Sheet
β-strand	7-10	4	1
β-strand	20-23	4	1

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Hepcidin	A	protein	25	Homo sapiens	P81172 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>2KEF_1 Hepcidin (chains A)
DTHFPICIFCCGCCHRSKCGMCCKT

Primary citation

Hepcidin revisited, disulfide connectivity, dynamics, and structure. Jordan, J.B., Poppe, L., Haniu, M. et al. J Biol Chem (2009) 284:24155-24167. DOI 10.1074/jbc.M109.017764 · PubMed

Other PDB entries of the same protein (UniProt P81172 (AlphaFold model), which also has an AlphaFold model), best resolution first:

3H0T 1.89 Å, Hepcidin-Fab complex
4QAE 2.1 Å, Crystal structure of an engineered lipocalin (Anticalin) in complex with human hepcidin
6WBV 2.5 Å, Structure of human ferroportin bound to hepcidin and cobalt in lipid nanodisc
1M4E Solution Structure of Hepcidin-20
1M4F Solution Structure of Hepcidin-25

Browse structure collections

About this viewer

MolViewer shows 2KEF directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.