2L2X: Thiostrepton

Thiostrepton, oxidized at CA-CB bond of residue 9. Determined by solution NMR. Released 2 Feb 2011.

Method

Solution NMR

Organism

Streptomyces azureus

Chains

1

Atoms

109

Mol. weight

1.73 kDa

Released

2 Feb 2011

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Molecules and chains

>2L2X_1 Thiostrepton (chains A)
XIASASCTTCICTCSCSX

Primary citation

NMR structures of thiostrepton derivatives for characterization of the ribosomal binding site. Jonker, H.R., Baumann, S., Wolf, A. et al. Angew Chem Int Ed Engl (2011) 50:3308-3312. DOI 10.1002/anie.201003582 · PubMed

Related structures

Other PDB entries of the same protein (UniProt P0C8P8 (AlphaFold model), which also has an AlphaFold model), best resolution first:

• 4HP2 0.64 Å, Invariom refinement of a new dimeric monoclinic 2 solvate of thiostrepton at 0.64…
• 1E9W 1.02 Å, Structure of the macrocycle thiostrepton solved using the anomalous dispersive…
• 9CQ0 1.5 Å, Event-based electron counting microED structure of thiostrepton from a single crystal
• 6MXF 1.91 Å, MicroED structure of thiostrepton at 1.9 A resolution
• 5D8H 2.8 Å, Crystal structure of the base of the ribosomal P stalk from methanococcus jannaschii…
• 3CF5 3.3 Å, Thiopeptide antibiotic Thiostrepton bound to the large ribosomal subunit of Deinococcus…
• 1OLN Model for thiostrepton antibiotic binding to L11 substrate from 50S ribosomal RNA
• 2JQ7 Model for thiostrepton binding to the ribosomal L11-RNA
• 2L2W Thiostrepton
• 2L2Y Thiostrepton, epimer form of residue 9
• 2L2Z Thiostrepton, reduced at N-CA bond of residue 14

Browse structure collections

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