Structure of the 2C/Ld/QL9 allogeneic complex. Determined by X-ray diffraction at 2.35 Å resolution. Released 24 Apr 2007.
Explore 2OI9 in 3D Show helices and sheets RCSB PDB PDBe
2OI9 contains 12 α-helices and 31 β-strands across 4 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 3-13 | 11 | 1 |
| α-helix | 20 | 1 | |
| β-strand | 21-28 | 8 | 1 |
| β-strand | 31-37 | 7 | 1 |
| β-strand | 45-47 | 3 | 1 |
| α-helix | 50-52 | 3 | |
| α-helix | 57-85 | 29 | |
| β-strand | 93-103 | 11 | 1 |
| β-strand | 109-118 | 10 | 1 |
| β-strand | 121-126 | 6 | 1 |
| β-strand | 133-135 | 3 | 1 |
| α-helix | 138-150 | 13 | |
| α-helix | 152-161 | 10 | |
| α-helix | 163-174 | 12 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 2-4 | 3 | 2 |
| β-strand | 9-12 | 4 | 3 |
| β-strand | 18-20 | 3 | 2 |
| β-strand | 23-25 | 3 | 2 |
| β-strand | 32-37 | 6 | 3 |
| β-strand | 44-49 | 6 | 3 |
| β-strand | 55-57 | 3 | 2 |
| α-helix | 59-61 | 3 | |
| β-strand | 62-67 | 6 | 2 |
| β-strand | 72-77 | 6 | 2 |
| α-helix | 82-84 | 3 | |
| β-strand | 86-93 | 8 | 3 |
| α-helix | 100-102 | 3 | |
| α-helix | 103 | 1 | |
| β-strand | 104-106 | 3 | 3 |
| β-strand | 110-114 | 5 | 3 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 4-7 | 4 | 4 |
| β-strand | 10-14 | 5 | 5 |
| β-strand | 19-25 | 7 | 4 |
| β-strand | 31-37 | 7 | 5 |
| β-strand | 44-49 | 6 | 5 |
| β-strand | 56-57 | 2 | 5 |
| β-strand | 65-68 | 4 | 4 |
| β-strand | 74-79 | 6 | 4 |
| α-helix | 84-86 | 3 | |
| β-strand | 88-95 | 8 | 5 |
| β-strand | 106-108 | 3 | 5 |
| β-strand | 112-117 | 6 | 5 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 3-8 | 6 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Major Histocompatibility Complex protein | A | protein | 179 | Mus musculus | P01897 (AlphaFold model) |
| T cell receptor alpha chain | B | protein | 113 | Mus musculus | P01738 (AlphaFold model) |
| T cell receptor beta chain | C | protein | 121 | Mus musculus | A2NTY6 (AlphaFold model) |
| peptide (GLN)(LEU)(SER)(PRO)(PHE)(PRO)(PHE)(ASP)(LEU) | Q | protein | 9 |
>2OI9_1 Major Histocompatibility Complex protein (chains A) GPHSMRYYETATSRRGLGEPRYTSVGYVDDKEFVRFDSDAENPRYEPQVPWMEQEGPEYW ERITQVAKGQEQWFRVNLRTLLGYYNQSAGGTHTLQRMYGCDVGSDGRLLRGYEQFAYDG CDYIALNEDLRTWTAADMAAQITRRKWEQAGAAEYYRAYLEGECVEWLHRYLKNGNATL
>2OI9_2 T cell receptor alpha chain (chains B) QSVTQPDARVTVSEGASLQLRCKYSYSATPYLFWYVQYPRQGPQLLLKYYSGDPVVQGVN GFEAEFSKSNSSFHLRKASVHRSDSAVYFCAVSGFASALTFGSGTKVIVLPYN
>2OI9_3 T cell receptor beta chain (chains C) EAAVTQSPRNKVAVTGEKVTLSCNQTNNHNNMYWYRQDTGHELRLIYYSYGAGSTEKGDI PDGYKASRPSQENFSLTLESATPSQTSVYFCASGGGGTLYFGAGTRLSVLSSALEHHHHH H
>2OI9_4 peptide (GLN)(LEU)(SER)(PRO)(PHE)(PRO)(PHE)(ASP)(LEU) (chains Q) QLSPFPFDL
How a single T cell receptor recognizes both self and foreign MHC. Colf, L.A., Bankovich, A.J., Hanick, N.A. et al. Cell (2007) 129:135-146. DOI 10.1016/j.cell.2007.01.048 · PubMed
Other PDB entries of the same protein (UniProt P01897 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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