Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-GAMMA1 complexed with a high affinity binding peptide. Determined by solution NMR. Released 26 Jan 1995.
Explore 2PLD in 3D Show helices and sheets RCSB PDB PDBe
2PLD contains 2 α-helices and 7 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 12-13 | 2 | 1 |
| α-helix | 20-27 | 8 | |
| β-strand | 33-38 | 6 | 1 |
| β-strand | 44-51 | 8 | 1 |
| β-strand | 54-56 | 3 | 1 |
| β-strand | 59-62 | 4 | 1 |
| β-strand | 67-68 | 2 | 1 |
| β-strand | 73-74 | 2 | 1 |
| α-helix | 77-84 | 8 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Phospholipase C gamma-1, C-terminal SH2 domain | A | protein | 105 | Bos taurus | P08487 (AlphaFold model) |
| Phosphopeptide from pdgf | B | protein | 12 | Bos taurus | P09619 (AlphaFold model) |
>2PLD_1 PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN (chains A) GSPGIHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRV QQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEENSS
>2PLD_2 PHOSPHOPEPTIDE FROM PDGF (chains B) DNDYIIPLPDPK
Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Pascal, S.M., Singer, A.U., Gish, G. et al. Cell (1994) 77:461-472. DOI 10.1016/0092-8674(94)90160-0 · PubMed
Other PDB entries of the same protein (UniProt P08487 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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