2QX5: Nucleoporin Nic96

Structure of nucleoporin Nic96. Determined by X-ray diffraction at 2.5 Å resolution. Released 25 Sept 2007.

Method

X-ray diffraction

Resolution

2.5 Å

Organism

Saccharomyces cerevisiae

Chains

2

Atoms

9,160

Mol. weight

151.83 kDa

Released

25 Sept 2007

Explore 2QX5 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2QX5 contains 78 α-helices and 12 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 40 helices, 6 β-strands

Molecules and chains

>2QX5_1 Nucleoporin NIC96 (chains A, B)
PGSEFELGNKGNNILNSNESRLNVNENNILREKFENYARIVFQFNNSRQANGNFDIANEF
ISILSSANGTRNAQLLESWKILESMKSKDINIVEVGKQYLEQQFLQYTDNLYKKNMNEGL
ATNVNKIKSFIDTKLKKADKSWKISNLTVINGVPIWALIFYLLRAGLIKEALQVLVENKA
NIKKVEQSFLTYFKAYASSKDHGLPVEYSTKLHTEYNQHIKSSLDGDPYRLAVYKLIGRC
DLSRKNIPAVTLSIEDWLWMHLMLIKEKDAENDPVYERYSLEDFQNIIISYGPSRFSNYY
LQTLLLSGLYGLAIDYTYTFSEMDAVHLAIGLASLKLFKIDSSTRLTKKPKRDIRFANIL
ANYTKSFRYSDPRVAVEYLVLITLNEGPTDVELCHEALRELVLETKEFTVLLGKIGRDGA
RIPGVIEERQPLLHVRDEKEFLHTITEQAARRADEDGRIYDSILLYQLAEEYDIVITLVN
SLLSDTLSASDLDQPLVGPDDNSETNPVLLARRMASIYFDNAGISRQIHVKNKEICMLLL
NISSIRELYFNKQWQETLSQMELLDLLPFSDELSARKKAQDFSNLDDNIVKNIPNLLIIT
LSCISNMIHILNESKYQSSTKGQQIDSLKNVARQCMIYAGMIQYRMPRETYSTLINIDVS
L

Primary citation

Crystal structure of nucleoporin Nic96 reveals a novel, intricate helical domain architecture. Jeudy, S., Schwartz, T.U. J Biol Chem (2007) 282:34904. DOI 10.1074/jbc.M705479200 · PubMed

Related structures

Other PDB entries of the same protein (UniProt P34077 (AlphaFold model), which also has an AlphaFold model), best resolution first:

• 6X07 2.1 Å, Nic96 from S. cerevisiae bound by VHH-SAN12
• 2RFO 2.6 Å, Crystral Structure of the nucleoporin Nic96
• 7WOO 3.71 Å, Cryo-EM structure of the inner ring protomer of the Saccharomyces cerevisiae nuclear…
• 7WOT 3.73 Å, Cryo-EM structure of the inner ring monomer of the Saccharomyces cerevisiae nuclear pore…
• 8TJ5 6.6 Å, Inner spoke ring of the yeast NPC
• 7N85 7.6 Å, Inner ring spoke from the isolated yeast NPC
• 7N9F 37.0 Å, Structure of the in situ yeast NPC
• 8ZZA Integrative structure and functional anatomy of a single spoke of a nuclear pore complex
• 8ZZB Integrative structure and functional anatomy of three spokes of a nuclear pore complex
• 8ZZC Integrative structure and functional anatomy of eight spokes of a nuclear pore complex
• 9A0F Integrative model of the wild type yeast nuclear pore complex
• 9A0G Integrative model of Nup116 knockout (at 25C) yeast nuclear pore complex

Browse structure collections

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