2V0W: NPH1-1

N- and C-terminal helices of oat LOV2 (404-546) are involved in light- induced signal transduction (cryo-trapped light structure of LOV2 (404-546)). Determined by X-ray diffraction at 1.7 Å resolution. Released 11 Dec 2007.

Method: X-ray diffraction
Resolution: 1.7 Å
Organism: AVENA SATIVA
Chains: 1
Atoms: 1,438
Mol. weight: 17.59 kDa
Ligands: FMN
Released: 11 Dec 2007

Explore 2V0W in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2V0W contains 6 α-helices and 5 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 6 helices, 5 β-strands

Element	Residues	Length	Sheet
α-helix	404-406	3
α-helix	408-410	3
β-strand	415-418	4	1
β-strand	427-430	4	1
α-helix	432-438	7
α-helix	450-453	4
α-helix	460-471	12
β-strand	476-483	8	1
β-strand	489-500	12	1
β-strand	506-516	11	1
α-helix	522-543	22

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
NPH1-1	A	protein	146	AVENA SATIVA	O49003 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>2V0W_1 NPH1-1 (chains A)
GEFLATTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYSREEILGRNCRFLQGPETDR
ATVRKIRDAIDNQTEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVQLDGTEHV
RDAAEREGVMLIKKTAENIDEAAKEL

Ligands and cofactors

ID	Name	Formula	Copies
FMN	Flavin mononucleotide	C17 H21 N4 O9 P	1

Water and common crystallization additives (GOL) are not listed.

Primary citation

N- and C-Terminal Flanking Regions Modulate Light-Induced Signal Transduction in the Lov2 Domain of the Blue Light Sensor Phototropin 1 from Avena Sativa. Halavaty, A.S., Moffat, K. Biochemistry (2007) 46:14001. DOI 10.1021/BI701543E · PubMed

Other PDB entries of the same protein (UniProt O49003 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7PGZ 0.9 Å, Structure of dark-adapted AsLOV2 Q513L
7PH0 0.98 Å, Structure of light-adapted AsLOV2 Q513L
7PGX 1.0 Å, Structure of dark-adapted AsLOV2 wild type
7PGY 1.09 Å, Structure of light-adapted AsLOV2 wild type
2V0U 1.4 Å, n- and c-terminal helices of oat lov2 (404-546) are involved in light-induced signal…
2V1B 1.55 Å, N- and C-terminal helices of oat LOV2 (404-546) are involved in light-induced signal…
2WKQ 1.6 Å, Structure of a photoactivatable Rac1 containing the Lov2 C450A Mutant
2V1A 1.65 Å, N- and C-terminal helices of oat LOV2 (404-546) are involved in light-induced signal…
6NTP 1.89 Å, PTP1B Domain of PTP1B-LOV2 Chimera
2WKP 1.9 Å, Structure of a photoactivatable Rac1 containing Lov2 Wildtype
4WF0 1.95 Å, Crystal Structure of iLID - an Improved Light-Inducible Dimer
5EFW 2.1 Å, Crystal structure of LOV2-Zdk1 - the complex of oat LOV2 and the affibody protein Zdark1

Browse structure collections

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