32QU: Human NUP98 APD

Human NUP98 APD (SG P41212). Determined by X-ray diffraction at 1.5 Å resolution. Released 29 Jul 2026.

Method: X-ray diffraction
Resolution: 1.5 Å
Organism: Homo sapiens
Chains: 1
Atoms: 1,374
Mol. weight: 17.4 kDa
Released: 29 Jul 2026

Explore 32QU in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

32QU contains 6 α-helices and 14 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 6 helices, 14 β-strands

Element	Residues	Length	Sheet
β-strand	718	1	1
β-strand	724-727	4	2
α-helix	730-735	6
β-strand	744-752	9	2
β-strand	756-765	10	2
β-strand	770	1	1
α-helix	771-774	4
β-strand	775-778	4	3
β-strand	781-784	4	3
α-helix	788-790	3
α-helix	791-793	3
β-strand	796	1	4
β-strand	799	1	4
β-strand	802-806	5	2
β-strand	812	1	5
β-strand	819	1	5
α-helix	823-829	7
α-helix	831-841	11
β-strand	845-850	6	2
β-strand	855-860	6	2

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Nuclear pore complex protein Nup98-Nup96	A	protein	152	Homo sapiens	P52948 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>32QU_1 Nuclear pore complex protein Nup98-Nup96 (chains A)
MHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNL
DDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINY
EGRLEAVSRKQGAQFKEYRPETGSWVFKVSHF

Primary citation

Human NUP98 APD (SG P41212). Kim, Y., Schallmayer, L., Knapp, S. et al. To be published.

Other PDB entries of the same protein (UniProt P52948 (AlphaFold model), which also has an AlphaFold model), best resolution first:

6BZM 0.9 Å, GFGNFGTS from low-complexity/FG repeat domain of Nup98, residues 116-123
9PLM 1.32 Å, TRIM21-NUP98 Molecular Glue Complex (MAN-021)
32QT 1.47 Å, Human NUP98 APD (SG P21)
9PLL 1.6 Å, TRIM21-NUP98 Molecular Glue Complex (MAN-056)
3MMY 1.65 Å, Structural and functional analysis of the interaction between the nucleoporin Nup98 and…
2Q5X 1.9 Å, Crystal Structure of the C-terminal domain of hNup98
7MNI 2.0 Å, Crystal structure of the N-terminal domain of NUP88 in complex with NUP98 C-terminal…
2Q5Y 2.3 Å, Crystal Structure of the C-terminal domain of hNup98
7F90 2.39 Å, Crystal structure of SARS auxiliary protein in complex with human nuclear protein
7VPG 2.49 Å, Crystal structure of the C-terminal tail of SARS-CoV-1 Orf6 complex with human…
8CI8 2.67 Å, Cryo-EM structure of the Nup98(298-327) fibril
7Q64 2.76 Å, Cryo-em structure of the Nup98 fibril polymorph 1

Browse structure collections

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