3FIA: Intersectin-1

Crystal structure of the EH 1 domain from human intersectin-1 protein. Northeast Structural Genomics Consortium target HR3646e. Determined by X-ray diffraction at 1.45 Å resolution. Released 30 Dec 2008.

Method
X-ray diffraction
Resolution
1.45 Å
Organism
Homo sapiens
Chains
1
Atoms
917
Mol. weight
13.95 kDa
Ligands
CA
Released
30 Dec 2008

Explore 3FIA in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

3FIA contains 8 α-helices and 4 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 8 helices, 4 β-strands

ElementResiduesLengthSheet
α-helix16-183
α-helix19-3113
β-strand3511
β-strand3811
β-strand39-4022
α-helix41-488
α-helix49-513
α-helix55-6511
β-strand72-7322
α-helix75-8915
α-helix92-954
α-helix100-1023

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Intersectin-1Aprotein121Homo sapiensQ15811 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>3FIA_1 Intersectin-1 (chains A)
MGHHHHHHSHVAQFPTPFGGSLDTWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQ
SGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAIS
S

Ligands and cofactors

IDNameFormulaCopies
CACalcium ionCa1

Water and common crystallization additives (SO4) are not listed.

Primary citation

Crystal structure of the EH 1 domain from human intersectin-1 protein. Vorobiev, S.M., Chen, Y., Seetharaman, J. et al. To be published.

Other PDB entries of the same protein (UniProt Q15811 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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