3FTH: NFLVHSS segment from Islet Amyloid Polypeptide
NFLVHSS segment from Islet Amyloid Polypeptide (IAPP or Amylin). Determined by X-ray diffraction at 1.84 Å resolution. Released 30 Jun 2009.
- Method
- X-ray diffraction
- Resolution
- 1.84 Å
- Organism
- Homo sapiens
- Chains
- 2
- Atoms
- 136
- Mol. weight
- 1.7 kDa
- Released
- 30 Jun 2009
Explore 3FTH in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
3FTH contains 0 α-helices and 2 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chains A and B: 0 helices, 1 β-strand
| Element | Residues | Length | Sheet |
|---|
| β-strand | 2-6 | 5 | 1 |
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| NFLVHSS heptapeptide from Islet Amyloid Polypeptide | A, B | protein | 7 | Homo sapiens | P10997 (AlphaFold model) |
Sequence of entity 1 (A, B), FASTA
>3FTH_1 NFLVHSS heptapeptide from Islet Amyloid Polypeptide (chains A, B)
NFLVHSS
Primary citation
Molecular mechanisms for protein-encoded inheritance. Wiltzius, J.J., Landau, M., Nelson, R. et al. Nat Struct Mol Biol (2009) 16:973-978. DOI 10.1038/nsmb.1643 · PubMed
Other PDB entries of the same protein (UniProt P10997 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 8YG2 1.25 Å, Crystal structure of amyloidogenic peptide Piv-NFGAIL-NH2 from Islet Amyloid Polypeptide
- 5KO0 1.4 Å, Human Islet Amyloid Polypeptide Segment 15-FLVHSSNNFGA-25 Determined by MicroED
- 3FPO 1.5 Å, HSSNNF segment from Islet Amyloid Polypeptide (IAPP or Amylin)
- 3FTK 1.5 Å, NVGSNTY segment from Islet Amyloid Polypeptide (IAPP or Amylin), hydrated crystal form
- 3FTL 1.6 Å, NVGSNTY segment from Islet Amyloid Polypeptide (IAPP or Amylin), dehydrated crystal form
- 3FTR 1.61 Å, Structure of an amyloid forming peptide SSTNVG from IAPP (alternate polymorph)
- 3DG1 1.66 Å, Segment SSTNVG derived from IAPP
- 3G7W 1.75 Å, Islet Amyloid Polypeptide (IAPP or Amylin) Residues 1 to 22 fused to Maltose Binding…
- 3FR1 1.85 Å, NFLVHS segment from Islet Amyloid Polypeptide (IAPP or Amylin)
- 3G7V 1.86 Å, Islet Amyloid Polypeptide (IAPP or Amylin) fused to Maltose Binding Protein
- 9CC5 1.87 Å, De novo design of high-affinity protein binders to bio active peptide Amylin
- 5KNZ 1.9 Å, Human Islet Amyloid Polypeptide Segment 19-SGNNFGAILSS-29 with Early Onset S20G Mutation…
Browse structure collections
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