8YG2: PDB entry 8YG2
Crystal structure of amyloidogenic peptide Piv-NFGAIL-NH2 from Islet Amyloid Polypeptide. Determined by X-ray diffraction at 1.25 Å resolution. Released 8 May 2024.
- Method
- X-ray diffraction
- Resolution
- 1.25 Å
- Organism
- Homo sapiens
- Chains
- 1
- Atoms
- 68
- Mol. weight
- 0.76 kDa
- Released
- 8 May 2024
Explore 8YG2 in 3D
Show helices and sheets
RCSB PDB
PDBe
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Amyloidogenic peptide from Islet Amyloid Polypeptide | A | protein | 8 | Homo sapiens | P10997 (AlphaFold model) |
Sequence of entity 1 (A), FASTA
>8YG2_1 Amyloidogenic peptide from Islet Amyloid Polypeptide (chains A)
XNFGAILX
Primary citation
Catalysis driven by an amyloid-substrate complex. Sawazaki, T., Sasaki, D., Sohma, Y. Proc Natl Acad Sci U S A (2024) 121:e2314704121-e2314704121. DOI 10.1073/pnas.2314704121 · PubMed
Other PDB entries of the same protein (UniProt P10997 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 5KO0 1.4 Å, Human Islet Amyloid Polypeptide Segment 15-FLVHSSNNFGA-25 Determined by MicroED
- 3FPO 1.5 Å, HSSNNF segment from Islet Amyloid Polypeptide (IAPP or Amylin)
- 3FTK 1.5 Å, NVGSNTY segment from Islet Amyloid Polypeptide (IAPP or Amylin), hydrated crystal form
- 3FTL 1.6 Å, NVGSNTY segment from Islet Amyloid Polypeptide (IAPP or Amylin), dehydrated crystal form
- 3FTR 1.61 Å, Structure of an amyloid forming peptide SSTNVG from IAPP (alternate polymorph)
- 3DG1 1.66 Å, Segment SSTNVG derived from IAPP
- 3G7W 1.75 Å, Islet Amyloid Polypeptide (IAPP or Amylin) Residues 1 to 22 fused to Maltose Binding…
- 3FTH 1.84 Å, NFLVHSS segment from Islet Amyloid Polypeptide (IAPP or Amylin)
- 3FR1 1.85 Å, NFLVHS segment from Islet Amyloid Polypeptide (IAPP or Amylin)
- 3G7V 1.86 Å, Islet Amyloid Polypeptide (IAPP or Amylin) fused to Maltose Binding Protein
- 9CC5 1.87 Å, De novo design of high-affinity protein binders to bio active peptide Amylin
- 5KNZ 1.9 Å, Human Islet Amyloid Polypeptide Segment 19-SGNNFGAILSS-29 with Early Onset S20G Mutation…
Browse structure collections
About this viewer
MolViewer shows 8YG2 directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.