3JRO: PDB entry 3JRO

NUP84-NUP145C-SEC13 edge element of the NPC lattice. Determined by X-ray diffraction at 4.0 Å resolution. Released 27 Oct 2009.

Method

X-ray diffraction

Resolution

4.0 Å

Organism

Saccharomyces cerevisiae

Chains

2

Atoms

8,671

Mol. weight

134.61 kDa

Released

27 Oct 2009

Explore 3JRO in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

3JRO contains 56 α-helices and 33 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 28 helices, 33 β-strands

Molecules and chains

>3JRO_1 Fusion Protein of Protein Transport Protein SEC13 and Nucleoporin NUP145 (chains A)
MVVIANAHNELIHDAVLDYYGKRLATCSSDKTIKIFEVEGETHKLIDTLTGHEGPVWRVD
WAHPKFGTILASCSYDGKVLIWKEENGRWSQIAVHAVHSASVNSVQWAPHEYGPLLLVAS
SDGKVSVVEFKENGTTSPIIIDAHAIGVNSASWAPATIEEDGEHNGTKESRKFVTGGADN
LVKIWKYNSDAQTYVLESTLEGHSDWVRDVAWSPTVLLRSYLASVSQDRTCIIWTQDNEQ
GPWKKTLLKEEKFPDVLWRASWSLSGNVLALSGGDNKVTLWKENLEGKWEPAGEVHQGGG
GSGGGGATSKEFDGPCQNEIDLLFSECNDEIDNAKLIMKERRFTASYTFAKFSTGSMLLT
KDIVGKSGVSIKRLPTELQRKFLFDDVYLDKEIEKVTIEARKSNPYPQISESSLLFKDAL
DYMEKTSSDYNLWKLSSILFDPVSYPYKTDNDQVKMALLKKERHCRLTSWIVSQIGPEIE
EKIRNSSNEIEQIFLYLLLNDVVRASKLAIESKNGHLSVLISYLGSNDPRIRDLAELQLQ
KWSTGGCSIDKNISKIYKLLSGSPFEGLFSLKELESEFSWLCLLNLTLCYGQIDEYSLES
LVQSHLDKFSLPYDDPIGVIFQLYAANENTEKLYKEVRQRTNALDVQFCWYLIQTLRFNG
TRVFSKETSDEATFAFAAQLEFAQLHGHSLFVSCFLNDDKAAEDTIKRLVMREITLLRAS
TNDHILNRLKIPSQLIFNAQALKDRYEGNYLSE

>3JRO_2 Nucleoporin NUP84 (chains C)
GSMELSPTYQTERFTKFSDTLKEFKIEQNNEQNPIDPFNIIREFRSAAGQLALDLANSGD
ESNVISSKDWELEARFWHLVELLLVFRNADLDLDEMELHPYNSRGLFEKKLMQDNKQLYQ
IWIVMVWLKENTYVMERPKNVPTSKWLNSITSGGLKSCDLDFPLRENTNVLDVKDKEEDH
IFFKYIYELILAGAIDEALEEAKLSDNISICMILCGIQEYLNPVIDTQIANEFNTQQGIK
KHSLWRRTVYSLSQQAGLDPYERAIYSYLSGAIPNQEVLQYSDWESDLHIHLNQILQTEI
ENYLLENNQVGTDELILPLPSHALTVQEVLNRVASRHPSESEHPIRVLMASVILDSLPSV
IHSSVEMLLDVVKGTEASNDIIDKPYLLRIVTHLAICLDIINPGSVEEVDKSKLITTYIS
LLKLQG

Primary citation

Molecular architecture of the Nup84-Nup145C-Sec13 edge element in the nuclear pore complex lattice. Brohawn, S.G., Schwartz, T.U. Nat Struct Mol Biol (2009) 16:1173-1177. DOI 10.1038/nsmb.1713 · PubMed

Related structures

Other PDB entries of the same protein (UniProt P49687 (AlphaFold model), which also has an AlphaFold model), best resolution first:

• 3KEP 1.82 Å, Crystal structure of the autoproteolytic domain from the nuclear pore complex component…
• 3KES 2.1 Å, Crystal structure of the autoproteolytic domain from the nuclear pore complex component…
• 3JRP 2.6 Å, SEC13 with NUP145C (AA109-179) insertion blade
• 3BG1 3.0 Å, Architecture of a Coat for the Nuclear Pore Membrane
• 3BG0 3.15 Å, Architecture of a Coat for the Nuclear Pore Membrane
• 3IKO 3.2 Å, Crystal structure of the heterotrimeric Sec13-Nup145C-Nup84 nucleoporin complex
• 4XMM 7.38 Å, Structure of the yeast coat nucleoporin complex, space group C2
• 4XMN 7.6 Å, Structure of the yeast coat nucleoporin complex, space group P212121
• 8TIE 8.1 Å, Double nuclear outer ring of Nup84-complexes from the yeast NPC
• 7N84 11.6 Å, Double nuclear outer ring from the isolated yeast NPC
• 7N9F 37.0 Å, Structure of the in situ yeast NPC
• 8ZZ1 Structure of the Nup84 sub-complex of the Nuclear Pore Complex

Browse structure collections

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