7N84: Nucleoporin NUP188

Double nuclear outer ring from the isolated yeast NPC. Determined by electron microscopy at 11.6 Å resolution. Released 26 Jan 2022.

Method: Electron microscopy
Resolution: 11.6 Å
Organism: Saccharomyces cerevisiae
Chains: 17
Atoms: 83,142
Mol. weight: 1351.74 kDa
Released: 26 Jan 2022

Explore 7N84 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7N84 contains 408 α-helices and 275 β-strands across 17 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain a: 32 helices, 35 β-strands

Element	Residues	Length	Sheet
β-strand	8	1	3
β-strand	25-27	3	4
β-strand	55-59	5	4
β-strand	68	1	5
β-strand	69-73	5	4
β-strand	78-81	4	4
β-strand	83	1	5
β-strand	93-96	4	4
β-strand	101	1	6
α-helix	105-107	3
β-strand	108-112	5	7
β-strand	116-122	7	7
β-strand	123	1	6
β-strand	128-134	7	7
β-strand	150-153	4	7
β-strand	163-170	8	8
β-strand	173-178	6	8
β-strand	183-188	6	8
β-strand	194-198	5	8
β-strand	223-229	7	9
β-strand	233-238	6	9
β-strand	243-247	5	9
β-strand	256	1	9
β-strand	297-304	8	10
β-strand	312-320	9	10
α-helix	321-322	2
α-helix	325-327	3
β-strand	330-337	8	11
β-strand	350-357	8	11
β-strand	360-366	7	11
β-strand	379	1	11
α-helix	407-414	8
α-helix	417-420	4
α-helix	442-451	10
β-strand	462-466	5	3
β-strand	470-474	5	3
β-strand	481-483	3	3
α-helix	489-491	3
α-helix	505-511	7
α-helix	514-517	4
α-helix	522-537	16
α-helix	546-556	11
α-helix	564-575	12
α-helix	579-589	11
β-strand	602	1	12
α-helix	609-633	25
α-helix	648-661	14
α-helix	676-681	6
β-strand	691	1	12
α-helix	696-709	14
α-helix	723-732	10
α-helix	752-761	10
α-helix	771-778	8
β-strand	793-795	3	13
β-strand	800-802	3	13
α-helix	808-811	4
α-helix	824-834	11
α-helix	838-842	5
α-helix	845-850	6
α-helix	867-874	8
α-helix	904-912	9
α-helix	919-921	3
α-helix	943-946	4
α-helix	948-953	6
α-helix	977-988	12
α-helix	993-1001	9
α-helix	1029-1031	3

Chain b: 35 helices, 4 β-strands

Element	Residues	Length	Sheet
β-strand	67-70	4	14
β-strand	78-82	5	14
β-strand	89-90	2	15
β-strand	91-93	3	14
α-helix	102-116	15
α-helix	135-138	4
α-helix	143-147	5
α-helix	152-162	11
α-helix	170-176	7
α-helix	180-185	6
α-helix	186-190	5
α-helix	204-208	5
α-helix	210-213	4
α-helix	218	1
α-helix	220	1
α-helix	223-225	3
α-helix	262-265	4
α-helix	272-277	6
α-helix	285-293	9
α-helix	301-303	3
α-helix	308-317	10
α-helix	328-339	12
α-helix	355-362	8
α-helix	392-396	5
α-helix	414-420	7
α-helix	467-470	4
α-helix	471-473	3
α-helix	482-486	5
α-helix	497-502	6
α-helix	507-510	4
α-helix	537-544	8
α-helix	545-547	3
α-helix	567-576	10
α-helix	599-602	4
α-helix	607-609	3
α-helix	626-631	6
α-helix	668-671	4
α-helix	697-700	4
α-helix	730-736	7

Chain c: 30 helices, 6 β-strands

Element	Residues	Length	Sheet
α-helix	131-141	11
β-strand	153	1	16
β-strand	159-162	4	16
β-strand	170-173	4	16
α-helix	187-194	8
β-strand	198-200	3	17
β-strand	209-212	4	17
α-helix	229-240	12
α-helix	243-245	3
α-helix	255-274	20
α-helix	277-284	8
α-helix	290-300	11
α-helix	303-306	4
α-helix	331-343	13
β-strand	350	1	18
α-helix	354-360	7
α-helix	381-391	11
α-helix	400-409	10
α-helix	423-426	4
α-helix	431-438	8
α-helix	447-460	14
α-helix	467-483	17
α-helix	487-493	7
α-helix	502-513	12
α-helix	515-517	3
α-helix	536-545	10
α-helix	552-560	9
α-helix	573-576	4
α-helix	588-595	8
α-helix	598-601	4
α-helix	603-605	3
α-helix	616-619	4
α-helix	620-622	3
α-helix	639-642	4
α-helix	643-645	3
α-helix	657-664	8

Chain d: 2 helices, 24 β-strands

Element	Residues	Length	Sheet
β-strand	14-17	4	19
β-strand	24-27	4	19
β-strand	32-38	7	19
β-strand	43-50	8	19
β-strand	56-60	5	20
α-helix	61-63	3
β-strand	70-74	5	20
β-strand	79-84	6	20
β-strand	89-95	7	20
β-strand	102-106	5	21
α-helix	107-109	3
β-strand	115-120	6	21
β-strand	124-129	6	21
β-strand	138-142	5	21
β-strand	148-153	6	22
β-strand	172-177	6	22
β-strand	182-188	7	22
β-strand	193-198	6	22
β-strand	207-212	6	23
β-strand	220-226	7	23
β-strand	231-236	6	23
β-strand	244-247	4	23
β-strand	260-262	3	24
β-strand	269-271	3	24
β-strand	281-283	3	25
β-strand	289-291	3	25

Chain e: 0 helices, 29 β-strands

Element	Residues	Length	Sheet
β-strand	4-5	2	15
β-strand	17	1	26
β-strand	23-27	5	26
β-strand	32-38	7	26
β-strand	45-52	8	26
β-strand	58	1	27
β-strand	62-64	3	28
β-strand	71-73	3	28
β-strand	75	1	29
β-strand	76	1	27
β-strand	81	1	29
β-strand	84-85	2	28
β-strand	99-100	2	28
β-strand	111-116	6	30
β-strand	123-129	7	30
β-strand	133-139	7	30
β-strand	149	1	30
β-strand	153-155	3	30
β-strand	171-173	3	31
β-strand	182-186	5	31
β-strand	191-196	6	31
β-strand	202-206	5	31
β-strand	215-221	7	32
β-strand	229-235	7	32
β-strand	240-246	7	32
β-strand	293-300	8	32
β-strand	309-312	4	33
β-strand	319-322	4	33
β-strand	328-329	2	33

Chain f: 34 helices, 1 β-strand

Element	Residues	Length	Sheet
α-helix	11-16	6
α-helix	36-55	20
α-helix	59-79	21
α-helix	97-99	3
α-helix	103-111	9
α-helix	114-124	11
α-helix	139-140	2
α-helix	146-149	4
β-strand	154	1	18
α-helix	160-163	4
α-helix	171-189	19
α-helix	193-201	9
α-helix	208-213	6
α-helix	240-251	12
α-helix	258-268	11
α-helix	282-304	23
α-helix	324-334	11
α-helix	336-339	4
α-helix	344-352	9
α-helix	355-361	7
α-helix	374-376	3
α-helix	383-399	17
α-helix	407-423	17
α-helix	457-467	11
α-helix	474-477	4
α-helix	508-511	4
α-helix	526-534	9
α-helix	581-594	14
α-helix	598-602	5
α-helix	618-625	8
α-helix	650-667	18
α-helix	670-673	4
α-helix	711-715	5
α-helix	718-721	4
α-helix	722-724	3

Chain g: 35 helices, 28 β-strands

Element	Residues	Length	Sheet
β-strand	67	1	34
β-strand	97-98	2	35
β-strand	105-108	4	35
β-strand	121-124	4	35
α-helix	135-137	3
β-strand	162-165	4	36
β-strand	172-175	4	36
β-strand	211-213	3	37
β-strand	219-222	4	37
β-strand	228-231	4	37
β-strand	233	1	38
β-strand	240	1	38
β-strand	272-273	2	39
β-strand	282-283	2	39
β-strand	284-286	3	40
β-strand	291-298	8	40
β-strand	303-311	9	40
α-helix	313-320	8
α-helix	328-331	4
β-strand	334-338	5	41
β-strand	347-353	7	41
β-strand	360-366	7	41
β-strand	379-383	5	41
β-strand	417-419	3	42
β-strand	426-428	3	42
β-strand	455-461	7	43
β-strand	464-469	6	43
β-strand	474-475	2	43
β-strand	479	1	34
α-helix	501-507	7
α-helix	516-524	9
α-helix	534-537	4
α-helix	557-565	9
α-helix	567-573	7
α-helix	587-590	4
α-helix	596-603	8
α-helix	612-619	8
α-helix	642-651	10
α-helix	663-678	16
α-helix	696-700	5
α-helix	719-728	10
α-helix	736-742	7
α-helix	775-787	13
α-helix	788-790	3
α-helix	802-805	4
α-helix	843-846	4
α-helix	869-877	9
α-helix	897-902	6
α-helix	917-930	14
α-helix	942-964	23
β-strand	970-971	2	44
α-helix	982-990	9
α-helix	1000-1004	5
β-strand	1009-1010	2	44
α-helix	1018-1024	7
α-helix	1034-1048	15
α-helix	1056-1067	12
α-helix	1070-1072	3
α-helix	1077-1078	2
α-helix	1092-1098	7
α-helix	1106-1121	16
α-helix	1125-1127	3
α-helix	1128-1137	10

Chain l: 33 helices, 43 β-strands

Element	Residues	Length	Sheet
β-strand	2-6	5	45
β-strand	9	1	46
β-strand	26-27	2	47
β-strand	57-61	5	48
β-strand	67-71	5	48
β-strand	79-81	3	47
β-strand	82-83	2	48
β-strand	93-96	4	47
β-strand	101	1	49
β-strand	108-112	5	50
β-strand	116-121	6	50
β-strand	123	1	49
β-strand	130-134	5	50
β-strand	163-168	6	51
β-strand	174-178	5	51
β-strand	182-188	7	51
β-strand	194-198	5	51
α-helix	199-200	2
β-strand	223-225	3	52
β-strand	229	1	52
β-strand	233-234	2	52
α-helix	236	1
β-strand	237-238	2	52
β-strand	242-247	6	52
β-strand	252-258	7	52
β-strand	280	1	53
β-strand	288-290	3	53
α-helix	291	1
β-strand	298-304	7	53
β-strand	312-319	8	53
β-strand	330-337	8	54
α-helix	339	1
β-strand	349-356	8	54
β-strand	364-368	5	54
β-strand	377-379	3	54
β-strand	380-382	3	45
α-helix	386-392	7
α-helix	407-414	8
β-strand	434	1	55
β-strand	439	1	55
β-strand	463-465	3	56
β-strand	471-473	3	56
β-strand	474-475	2	46
β-strand	480-481	2	46
β-strand	484-485	2	45
α-helix	489-495	7
α-helix	505-517	13
α-helix	524-537	14
α-helix	546-553	8
α-helix	554-558	5
α-helix	564-574	11
α-helix	581-584	4
β-strand	602-603	2	57
α-helix	609-611	3
α-helix	617-639	23
α-helix	653-668	16
α-helix	675-680	6
β-strand	690-691	2	57
α-helix	697-707	11
α-helix	723-726	4
α-helix	752-766	15
α-helix	770-776	7
β-strand	791-793	3	58
β-strand	802-804	3	58
α-helix	808-812	5
α-helix	813-815	3
α-helix	824-831	8
α-helix	838-846	9
α-helix	864-874	11
α-helix	876-878	3
α-helix	909-911	3
α-helix	918-921	4
α-helix	942-949	8
α-helix	976-981	6
α-helix	995-998	4
α-helix	1030-1032	3

8 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Nucleoporin NUP188	X	protein	1655	Saccharomyces cerevisiae	P52593 (AlphaFold model)
unknown	Y, Z	protein	63	Saccharomyces cerevisiae
Nucleoporin NUP120	a, l	protein	1037	Saccharomyces cerevisiae	P35729 (AlphaFold model)
Nucleoporin NUP85	b, m	protein	744	Saccharomyces cerevisiae	P46673 (AlphaFold model)
Nucleoporin 145c	c, n	protein	712	Saccharomyces cerevisiae	P49687 (AlphaFold model)
Protein transport protein SEC13	d, o	protein	297	Saccharomyces cerevisiae	Q04491
Nucleoporin SEH1	e, p	protein	349	Saccharomyces cerevisiae	P53011
Nucleoporin NUP84	f, q	protein	726	Saccharomyces cerevisiae	P52891
Nucleoporin NUP133	g, r	protein	1157	Saccharomyces cerevisiae	P36161

Sequence of entity 1 (X), FASTA

>7N84_1 Nucleoporin NUP188 (chains X)
MATPSFGNSSPQLTFTHVANFMNDAAADVSAVDAKQLAQIRQFLKANKTNLIESLNTIRQ
NVTSSGDHNKLRSTIANLLQINVDNDPFFAQSEDLSHAVEFFMSERSSRLHIVYSLLVNP
DIDLETYSFIDNDRFNVVGKLISIISSVIQNYDIITASSLAHDYNNDQDMFTIVSLVQLK
KFSDLKFILQILQILNLMILNTKVPVDIVNQWFLQYQNQFVEFCRNINSTDKSIDTSSLQ
LYKFQNFQDLSYLSETLISRISSLFTITTILILGLNTSIAQFDIQSPLYMDTETFDTVNS
ALENDVATNIVNEDPIFHPMIHYSWSFILYYRRALQSSESFDDSDITKFALFAESHDVLQ
KLNTLSEILSFDPVYTTVITVFLEFSLNFIPITASTSRVFAKIISKAPEQFIENFLTNDT
FEKKLSIIKAKLPLLNESLIPLINLALIDTEFANFELKDICSFAVTKSSLNDLDYDLIAD
TITNSSSSSDIIVPDLIELKSDLLVAPPLENENSNCLLSIPKSTKGKILTIKQQQQQQQQ
QNGQQPPTTSNLIIFLYKFNGWSLVGRILQNLLHSYMEKGTQLDDLQHELMISIIKLVTN
VVDPKTSIEKSSEILSYLSNSLDTSASTINGASIIQVIFEIFEISLQRKDYTSIVQCCEF
MTMLTPNYLHLVSSYLNKSDLLDKYGKTGLSNMILGSVELSTGDYTFTIQLLKLTKVFIR
ESLSLKNIHISKRSKIDIINKLILHAIHIFESYYNWKYNNFLQKFEIAFHLTLIFYDVLH
DVFTINPHQKDQLIISSSANKLLQLFLTPMDSIDLAPNTLTNILISPLNTTTKILGDKIL
GNLYSKVMNNSFKLCTLLIAIRGSNRDLKPSNLEKLLFINSSKLVDVYTLPSYVHFKVQI
IELLSYLVEAPWNDDYPFLLSFLGEAKSMAFLKEVLSDLSSPVQDWNLLRSLYIFFTTLL
ESKQDGLSILFLTGQFASNKKINDESSIDKKSSILTVLQKNSLLLDSTPEEVSCKLLETI
TYVLNTWTNSKIFIKDPKFVNSLLAKLKDSKKLFQKKENLTRDETVSLIKKYKLISRIVE
IFALCIYNSTDSNSEILNFLNQEDLFELVHHFFQIDGFNKTFHDELNLKFKEKWPSLELQ
SFQKIPLSRINENENFGYDIPLLDIVLKADRSWNEPSKSQTNFKEEITDASLNLQYVNYE
ISTAKAWGALITTFVKRSTVPLNDGFVDLVEHFLKLNIDFGSDKQMFTQIYLERIELSFY
ILYSFKLSGKLLKEEKIIELMNKIFTIFKSGEIDFIKNIGKSLKNNFYRPLLRSVLVLLE
LVSSGDRFIELISDQLLEFFELVFSKGVYLILSEILCQINKCSTRGLSTDHTTQIVNLED
NTQDLLLLLSLFKKITNVNPSKNFNVILASSLNEVGTLKVILNLYSSAHLIRINDEPILG
QITLTFISELCSIEPIAAKLINSGLYSVLLESPLSVAIQQGDIKPEFSPRLHNIWSNGLL
SIVLLLLSQFGIKVLPETCLFVSYFGKQIKSTIYNWGDNKLAVSSSLIKETNQLVLLQKM
LNLLNYQELFIQPKNSDDQQEAVELVIGLDSEHDKKRLSAALSKFLTHPKYLNSRIIPTT
LEEQQQLEDESSRLEFVKGISRDIKALQDSLFKDV

Sequence of entity 2 (Y, Z), FASTA

>7N84_2 unknown (chains Y, Z)
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX

Sequence of entity 3 (a, l), FASTA

>7N84_3 Nucleoporin NUP120 (chains a, l)
MACLSRIDANLLQYYEKPEPNNTVDLYVSNNSNNNGLKEGDKSISTPVPQPYGSEYSNCL
LLSNSEYICYHFSSRSTLLTFYPLSDAYHGKTINIHLPNASMNQRYTLTIQEVEQQLLVN
VILKDGSFLTLQLPLSFLFSSANTLNGEWFHLQNPYDFTVRVPHFLFYVSPQFSVVFLED
GGLLGLKKVDGVHYEPLLFNDNSYLKSLTRFFSRSSKSDYDSVISCKLFHERYLIVLTQN
CHLKIWDLTSFTLIQDYDMVSQSDSDPSHFRKVEAVGEYLSLYNNTLVTLLPLENGLFQM
GTLLVDSSGILTYTFQNNIPTNLSASAIWSIVDLVLTRPLELNVEASYLNLIVLWKSGTA
SKLQILNVNDESFKNYEWIESVNKSLVDLQSEHDLDIVTKTGDVERGFCNLKSRYGTQIF
ERAQQILSENKIIMAHNEDEEYLANLETILRDVKTAFNEASSITLYGDEIILVNCFQPYN
HSLYKLNTTVENWFYNMHSETDGSELFKYLRTLNGFASTLSNDVLRSISKKFLDIITGEL
PDSMTTVEKFTDIFKNCLENQFEITNLKILFDELNSFDIPVVLNDLINNQMKPGIFWKKD
FISAIKFDGFTSIISLESLHQLLSIHYRITLQVLLTFVLFDLDTEIFGQHISTLLDLHYK
QFLLLNLYRQDKCLLAEVLLKDSSEFSFGVKFFNYGQLIAYIDSLNSNVYNASITENSFF
MTFFRSYIIENTSHKNIRFFLENVECPFYLRHNEVQEFMFAMTLFSCGNFDQSYEIFQLH
DYPEAINDKLPTFLEDLKSENYHGDSIWKDLLCTFTVPYRHSAFYYQLSLLFDRNNSQEF
ALKCISKSAEYSLKEIQIEELQDFKEKQHIHYLNLLIHFRMFEEVLDVLRLGHECLSDTV
RTNFLQLLLQEDIYSRDFFSTLLRLCNAHSDNGELYLRTVDIKIVDSILSQNLRSGDWEC
FKKLYCFRMLNKSERAAAEVLYQYILMQADLDVIRKRKCYLMVINVLSSFDSAYDQWILN
GSKVVTLTDLRDELRGL

Sequence of entity 4 (b, m), FASTA

>7N84_4 Nucleoporin NUP85 (chains b, m)
MTIDDSNRLLMDVDQFDFLDDGTAQLSNNKTDEEEQLYKRDPVSGAILVPMTVNDQPIEK
NGDKMPLKFKLGPLSYQNMAFITAKDKYKLYPVRIPRLDTSKEFSAYVSGLFEIYRDLGD
DRVFNVPTIGVVNSNFAKEHNATVNLAMEAILNELEVFIGRVKDQDGRVNRFYELEESLT
VLNCLRTMYFILDGQDVEENRSEFIESLLNWINRSDGEPDEEYIEQVFSVKDSTAGKKVF
ETQYFWKLLNQLVLRGLLSQAIGCIERSDLLPYLSDTCAVSFDAVSDSIELLKQYPKDSS
STFREWKNLVLKLSQAFGSSATDISGELRDYIEDFLLVIGGNQRKILQYSRTWYESFCGF
LLYYIPSLELSAEYLQMSLEANVVDITNDWEQPCVDIISGKIHSILPVMESLDSCTAAFT
AMICEAKGLIENIFEGEKNSDDYSNEDNEMLEDLFSYRNGMASYMLNSFAFELCSLGDKE
LWPVAIGLIALSATGTRSAKKMVIAELLPHYPFVTNDDIEWMLSICVEWRLPEIAKEIYT
TLGNQMLSAHNIIESIANFSRAGKYELVKSYSWLLFEASCMEGQKLDDPVLNAIVSKNSP
AEDDVIIPQDILDCVVTNSMRQTLAPYAVLSQFYELRDREDWGQALRLLLLLIEFPYLPK
HYLVLLVAKFLYPIFLLDDKKLMDEDSVATVIEVIETKWDDADEKSSNLYETIIEADKSL
PSSMATLLKNLRKKLNFKLCQAFM

Sequence of entity 5 (c, n), FASTA

>7N84_5 Nucleoporin 145c (chains c, n)
SIWGLVNEEDAEIDEDDLSKQEDGGEQPLRKVRTLAQSKPSDKEVILKTDGTFGTLSGKD
DSIVEEKAYEPDLSDADFEGIEASPKLDVSKDWVEQLILAGSSLRSVFATSKEFDGPCQN
EIDLLFSECNDEIDNAKLIMKERRFTASYTFAKFSTGSMLLTKDIVGKSGVSIKRLPTEL
QRKFLFDDVYLDKEIEKVTIEARKSNPYPQISESSLLFKDALDYMEKTSSDYNLWKLSSI
LFDPVSYPYKTDNDQVKMALLKKERHCRLTSWIVSQIGPEIEEKIRNSSNEIEQIFLYLL
LNDVVRASKLAIESKNGHLSVLISYLGSNDPRIRDLAELQLQKWSTGGCSIDKNISKIYK
LLSGSPFEGLFSLKELESEFSWLCLLNLTLCYGQIDEYSLESLVQSHLDKFSLPYDDPIG
VIFQLYAANENTEKLYKEVRQRTNALDVQFCWYLIQTLRFNGTRVFSKETSDEATFAFAA
QLEFAQLHGHSLFVSCFLNDDKAAEDTIKRLVMREITLLRASTNDHILNRLKIPSQLIFN
AQALKDRYEGNYLSEVQNLLLGSSYDLAEMAIVTSLGPRLLLSNNPVQNNELKTLREILN
EFPDSERDKWSVSINVFEVYLKLVLDNVETQETIDSLISGMKIFYDQYKHCREVAACCNV
MSQEIVSKILEKNNPSIGDSKAKLLELPLGQPEKAYLRGEFAQDLMKCTYKI

Sequence of entity 6 (d, o), FASTA

>7N84_6 Protein transport protein SEC13 (chains d, o)
MVVIANAHNELIHDAVLDYYGKRLATCSSDKTIKIFEVEGETHKLIDTLTGHEGPVWRVD
WAHPKFGTILASCSYDGKVLIWKEENGRWSQIAVHAVHSASVNSVQWAPHEYGPLLLVAS
SDGKVSVVEFKENGTTSPIIIDAHAIGVNSASWAPATIEEDGEHNGTKESRKFVTGGADN
LVKIWKYNSDAQTYVLESTLEGHSDWVRDVAWSPTVLLRSYLASVSQDRTCIIWTQDNEQ
GPWKKTLLKEEKFPDVLWRASWSLSGNVLALSGGDNKVTLWKENLEGKWEPAGEVHQ

Sequence of entity 7 (e, p), FASTA

>7N84_7 Nucleoporin SEH1 (chains e, p)
MQPFDSGHDDLVHDVVYDFYGRHVATCSSDQHIKVFKLDKDTSNWELSDSWRAHDSSIVA
IDWASPEYGRIIASASYDKTVKLWEEDPDQEECSGRRWNKLCTLNDSKGSLYSVKFAPAH
LGLKLACLGNDGILRLYDALEPSDLRSWTLTSEMKVLSIPPANHLQSDFCLSWCPSRFSP
EKLAVSALEQAIIYQRGKDGKLHVAAKLPGHKSLIRSISWAPSIGRWYQLIATGCKDGRI
RIFKITEKLSPLASEESLTNSNMFDNSADVDMDAQGRSDSNTEEKAELQSNLQVELLSEH
DDHNGEVWSVSWNLTGTILSSAGDDGKVRLWKATYSNEFKCMSVITAQQ

Sequence of entity 8 (f, q), FASTA

>7N84_8 Nucleoporin NUP84 (chains f, q)
MELSPTYQTERFTKFSDTLKEFKIEQNNEQNPIDPFNIIREFRSAAGQLALDLANSGDES
NVISSKDWELEARFWHLVELLLVFRNADLDLDEMELHPYNSRGLFEKKLMQDNKQLYQIW
IVMVWLKENTYVMERPKNVPTSKWLNSITSGGLKSCDLDFPLRENTNVLDVKDKEEDHIF
FKYIYELILAGAIDEALEEAKLSDNISICMILCGIQEYLNPVIDTQIANEFNTQQGIKKH
SLWRRTVYSLSQQAGLDPYERAIYSYLSGAIPNQEVLQYSDWESDLHIHLNQILQTEIEN
YLLENNQVGTDELILPLPSHALTVQEVLNRVASRHPSESEHPIRVLMASVILDSLPSVIH
SSVEMLLDVVKGTEASNDIIDKPYLLRIVTHLAICLDIINPGSVEEVDKSKLITTYISLL
KLQGLYENIPIYATFLNESDCLEACSFILSSLEDPQVRKKQIETINFLRLPASNILRRTT
QRVFDETEQEYSPSNEISISFDVNNIDMHLIYGVEWLIEGKLYVDAVHSIIALSRRFLLN
GRVKALEQFMERNNIGEICKNYELEKIADNISKDENEDQFLEEITQYEHLIKGIREYEEW
QKSVSLLSSESNIPTLIEKLQGFSKDTFELIKTFLVDLTSSNFADSADYEILYEIRALYT
PFLLMELHKKLVEAAKLLKIPKFISEALAFTSLVANENDKIYLLFQSSGKLKEYLDLVAR
TATLSN

Sequence of entity 9 (g, r), FASTA

>7N84_9 Nucleoporin NUP133 (chains g, r)
MSEKKVHLRLRKELSVPIAVVENESLAQLSYEEESQASLMDISMEQQQLRLHSHFDNSKV
FTENNRYIVKTLQTDYSSGFSNDDELNGYIDMQIGYGLVNDHKKVYIWNIHSTQKDTPYI
TVPFRSDDNDEIAVAPRCILTFPATMDESPLALNPNDQDETGGLIIIKGSKAIYYEDINS
INNLNFKLSEKFSHELELPINSSGGEKCDLMLNCEPAGIVLSTNMGRIFFITIRNSMGKP
QLKLGKLLNKPFKLGIWSKIFNTNSSVVSLRNGPILGKGTRLVYITTNKGIFQTWQLSAT
NSHPTKLIDVNIYEAILESLQDLYPFAHGTLKIWDSHPLQDESSQLFLSSIYDSSCNETY
YILSTIIFDSSSNSFTIFSTYRLNTFMESITDTKFKPKIFIPQMENANDTNEVTSILVMF
PNAVVITQVNSKLDSSYSMRRKWEDIVSLRNDIDIIGSGYDSKSLYVLTKQMGVLQFFVK
ENEETNSKPEVGFVKSHVDQAVYFSKINANPIDFNLPPEISLDQESIEHDLKLTSEEIFH
SNGKYIPPMLNTLGQHLSVRKEFFQNFLTFVAKNFNYKISPELKLDLIEKFEILNCCIKF
NSIIRQSDVLNDIWEKTLSNYNLTQNEHLTTKTVVINSPDVFPVIFKQFLNHVVFVLFPS
QNQNFKLNVTNLINLCFYDGILEEGEKTIRYELLELDPMEVDTSKLPWFINFDYLNCINQ
CFFDFTFACEEEGSLDSYKEGLLKIVKILYYQFNQFKIWINTQPVKSVNANDNFININNL
YDDNHLDWNHVLCKVNLKEQCIQIAEFYKDLSGLVQTLQTLDQNDSTTVSLYETFFNEFP
KEFSFTLFEYLIKHKKLNDLIFRFPQQHDVLIQFFQESAPKYGHVAWIQQILDGSYADAM
NTLKNITVDDSKKGESLSECELHLNVAKLSSLLVEKDNLDINTLRKIQYNLDTIDAEKNI
SNKLKKGEVQICKRFKNGSIREVFNILVEELKSTTVVNLSDLVELYSMLDDEESLFIPLR
LLSVDGNLLNFEVKKFLNALVWRRIVLLNASNEGDKLLQHIVKRVFDEELPKNNDFPLPS
VDLLCDKSLLTPEYISETYGRFPIDQNAIREEIYEEISQVETLNSDNSLEIKLHSTIGSV
AKEKNYTINYETNTVEY

Primary citation

Comprehensive structure and functional adaptations of the yeast nuclear pore complex. Akey, C.W., Singh, D., Ouch, C. et al. Cell (2022) 185:361-378.e25. DOI 10.1016/j.cell.2021.12.015 · PubMed

Other PDB entries of the same protein (UniProt P52593 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7WO9 2.81 Å, Cryo-EM structure of full-length Nup188
7WOO 3.71 Å, Cryo-EM structure of the inner ring protomer of the Saccharomyces cerevisiae nuclear…
7WOT 3.73 Å, Cryo-EM structure of the inner ring monomer of the Saccharomyces cerevisiae nuclear pore…
8TJ5 6.6 Å, Inner spoke ring of the yeast NPC
7N85 7.6 Å, Inner ring spoke from the isolated yeast NPC
7N9F 37.0 Å, Structure of the in situ yeast NPC
8ZZA Integrative structure and functional anatomy of a single spoke of a nuclear pore complex
8ZZB Integrative structure and functional anatomy of three spokes of a nuclear pore complex
8ZZC Integrative structure and functional anatomy of eight spokes of a nuclear pore complex
9A0F Integrative model of the wild type yeast nuclear pore complex
9A0G Integrative model of Nup116 knockout (at 25C) yeast nuclear pore complex
9A0H Integrative model of Nup116 knockout (at 37C) yeast nuclear pore complex

Browse structure collections

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