3K82: Third PDZ domain of PSD-95

Crystal Structure of the third PDZ domain of PSD-95. Determined by X-ray diffraction at 1.4 Å resolution. Released 7 Apr 2010.

Method: X-ray diffraction
Resolution: 1.4 Å
Organism: Homo sapiens
Chains: 1
Atoms: 868
Mol. weight: 10.94 kDa
Ligands: PO4
Released: 7 Apr 2010

Explore 3K82 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

3K82 contains 3 α-helices and 8 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 3 helices, 8 β-strands

Element	Residues	Length	Sheet
β-strand	312-317	6	1
β-strand	319	1	2
β-strand	322	1	2
β-strand	325-331	7	1
β-strand	334-341	8	1
α-helix	346-350	5
β-strand	357-362	6	1
β-strand	365-366	2	1
α-helix	372-381	10
β-strand	385-392	8	1
α-helix	394-401	8

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Disks large homolog 4	A	protein	98	Homo sapiens	P78352 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>3K82_1 Disks large homolog 4 (chains A)
EDIPREPRRIVIHRGSTGLGFNIVGGENGEGIFISFILAGGPADLSGELRKGDQILSVNG
VDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEA

Ligands and cofactors

ID	Name	Formula	Copies
PO4	Phosphate ion	O4 P	1

Water and common crystallization additives (GOL, EPE) are not listed.

Primary citation

Novel conformational aspects of the third PDZ domain of the neuronal post-synaptic density-95 protein revealed from two 1.4A X-ray structures. Camara-Artigas, A., Murciano-Calles, J., Gavira, J.A. et al. J Struct Biol (2010) 170:565-569. DOI 10.1016/j.jsb.2010.03.005 · PubMed

Other PDB entries of the same protein (UniProt P78352 (AlphaFold model), which also has an AlphaFold model), best resolution first:

9TNG 0.95 Å, Crystal Structure of the third PDZ domain of PSD-95 protein E401R mutant
6QJL 1.04 Å, Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group P21
6QJK 1.05 Å, Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group P43
8AH5 1.25 Å, Crystal Structure of the third PDZ domain of PSD-95 protein in the space group P212121…
8AH7 1.25 Å, Crystal Structure of the third PDZ domain of PSD-95 protein in the space group P212121…
3I4W 1.35 Å, Crystal Structure of the third PDZ domain of PSD-95
9TNF 1.45 Å, Crystal Structure of the third PDZ domain of PSD-95 protein Y397E mutant
8AH4 1.48 Å, Crystal Structure of the third PDZ domain of PSD-95 protein in the space group P3112 at…
6QJF 1.5 Å, Crystal Structure of the third PDZ domain of PSD-95 protein D332P mutant: space group…
6QJI 1.5 Å, Crystal Structure of the third PDZ domain of PSD-95 protein: space group P3112
8AH8 1.5 Å, Crystal Structure of the third PDZ domain of PSD-95 protein in the space group P3121 at…
6QJD 1.55 Å, Crystal Structure of the truncated form of the third PDZ domain of PSD-95: residues…

Browse structure collections

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