3LX0: Thermonuclease

Crystal structure of Staphylococcal nuclease variant Delta+PHS D21N at cryogenic temperature. Determined by X-ray diffraction at 1.5 Å resolution. Released 16 Feb 2011.

Method
X-ray diffraction
Resolution
1.5 Å
Organism
Staphylococcus aureus
Chains
1
Atoms
1,312
Mol. weight
16.64 kDa
Ligands
THP, PO4
Released
16 Feb 2011

Explore 3LX0 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

3LX0 contains 7 α-helices and 11 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 7 helices, 11 β-strands

ElementResiduesLengthSheet
α-helix4-63
β-strand10-1231
β-strand13-1972
β-strand22-2762
β-strand30-3672
β-strand39-4023
α-helix41-433
α-helix55-6713
β-strand72-7541
β-strand8212
β-strand88-9032
β-strand91-9441
β-strand97-9821
α-helix99-1057
β-strand110-11123
α-helix116-1183
α-helix122-13413
α-helix138-1403

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
ThermonucleaseAprotein143Staphylococcus aureusP00644 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>3LX0_1 Thermonuclease (chains A)
ATSTKKLHKEPATLIKAIDGNTVKLMYKGQPMTFRLLLVDTPEFNEKYGPEASAFTKKMV
ENAKKIEVEFDKGQRTDKYGRGLAYIYADGKMVNEALVRQGLAKVAYVYKGNNTHEQLLR
KAEAQAKKEKLNIWSEDNADSGQ

Ligands and cofactors

IDNameFormulaCopies
THPThymidine-3',5'-diphosphateC10 H16 N2 O11 P21
PO4Phosphate ionO4 P1

Primary citation

Cooperative Proton Binding in a Cluster of Carboxylic Residues. Doctrow, B.M., Schlessman, J.L., Garcia-Moreno, E.B. et al. To be published.

Other PDB entries of the same protein (UniProt P00644 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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