3TO8: Heterogeneous nuclear ribonucleoprotein L

Crystal structure of the two C-terminal RRM domains of heterogeneous nuclear ribonucleoprotein L (hnRNP L). Determined by X-ray diffraction at 1.82 Å resolution. Released 7 Mar 2012.

Method
X-ray diffraction
Resolution
1.82 Å
Organism
Homo sapiens
Chains
1
Atoms
1,697
Mol. weight
25 kDa
Released
7 Mar 2012

Explore 3TO8 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

3TO8 contains 6 α-helices and 15 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 6 helices, 15 β-strands

ElementResiduesLengthSheet
β-strand383-38751
α-helix396-4038
β-strand409-41461
β-strand421-42661
α-helix429-43911
β-strand442-44432
β-strand447-44932
β-strand450-45341
β-strand46613
β-strand47213
β-strand474-47631
α-helix488-4914
β-strand502-50874
α-helix514-52411
α-helix527-5293
β-strand531-53444
β-strand543-54864
α-helix552-56211
β-strand566-56725
β-strand576-57725
β-strand579-58244

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Heterogeneous nuclear ribonucleoprotein LAprotein218Homo sapiensP14866 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>3TO8_1 Heterogeneous nuclear ribonucleoprotein L (chains A)
MGHHHHHHDSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYA
VDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQA
AKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSERSSSGLLEWES
KSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS

Primary citation

Crystal structure of the two C-terminal RRM domains of heterogeneous nuclear ribonucleoprotein L (hnRNP L). Zhang, W.J., Zeng, F.X., Liu, Y.W. et al. To be published.

Other PDB entries of the same protein (UniProt P14866 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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