3WRP: Trp repressor

Flexibility of the DNA-binding domains of trp repressor. Determined by X-ray diffraction at 1.8 Å resolution. Released 16 Apr 1988.

Method: X-ray diffraction
Resolution: 1.8 Å
Organism: Escherichia coli
Chains: 1
Atoms: 884
Mol. weight: 12.37 kDa
Released: 16 Apr 1988

Explore 3WRP in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

3WRP contains 6 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 6 helices, 0 β-strands

Element	Residues	Length
α-helix	12-30	19
α-helix	35-42	8
α-helix	45-63	19
α-helix	68-75	8
α-helix	79-90	12
α-helix	94-104	11

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Trp repressor	A	protein	108	Escherichia coli	P0A881 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>3WRP_1 TRP REPRESSOR (chains A)
MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTRVRIVEE
LLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEEVLLKSD

Primary citation

Flexibility of the DNA-binding domains of trp repressor. Lawson, C.L., Zhang, R.G., Schevitz, R.W. et al. Proteins (1988) 3:18-31. DOI 10.1002/prot.340030103 · PubMed

Other PDB entries of the same protein (UniProt P0A881 (AlphaFold model), which also has an AlphaFold model), best resolution first:

6ENI 1.1 Å, Tryptophan Repressor TrpR from E.coli variant T44L S88Y with Indole-3-acetic acid as…
6ENN 1.17 Å, Tryptophan Repressor TrpR from E.coli variant T44L T81M N87G S88Y with Indole-3-acetic…
6FAL 1.2 Å, Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid as ligand
1JHG 1.3 Å, Trp repressor mutant V58I
6ELG 1.38 Å, Tryptophan Repressor TrpR from E.coli variant M42F T44L T81I S88Y with…
6F9K 1.4 Å, Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand
6ELB 1.44 Å, Tryptophan Repressor TrpR from E.coli variant M42F T44L T81M N87G S88Y with…
6EKP 1.46 Å, Tryptophan Repressor TrpR from E.coli variant T44L T81M S88Y with Indole-3-acetic acid…
3SSX 1.58 Å, E. coli trp aporeporessor L75F mutant
2OZ9 1.65 Å, E. coli TRP holorepressor, orthorhombic crystal form
6F7G 1.66 Å, Tryptophan Repressor TrpR from E.coli with 5-Methyltryptamine
3SSW 1.67 Å, E. coli trp aporepressor

Browse structure collections

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