4HP2: Thiostrepton
Invariom refinement of a new dimeric monoclinic 2 solvate of thiostrepton at 0.64 angstrom resolution. Determined by X-ray diffraction at 0.64 Å resolution. Released 2 Oct 2013.
- Method
- X-ray diffraction
- Resolution
- 0.64 Å
- Organism
- Streptomyces azureus
- Chains
- 2
- Atoms
- 397
- Mol. weight
- 4.64 kDa
- Ligands
- DMF, ETZ
- Released
- 2 Oct 2013
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RCSB PDB
PDBe
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Thiostrepton | A, B | protein | 19 | Streptomyces azureus | P0C8P8 (AlphaFold model) |
Sequence of entity 1 (A, B), FASTA
>4HP2_1 Thiostrepton (chains A, B)
XIASASCTTCICTCSCSSX
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| DMF | Dimethylformamide | C3 H7 N O | 8 |
| ETZ | diethyl ether | C4 H10 O | 6 |
Primary citation
Invariom refinement of a new monoclinic solvate of thiostrepton at 0.64 angstrom resolution. Propper, K., Holstein, J.J., Hubschle, C.B. et al. Acta Crystallogr D Biol Crystallogr (2013) 69:1530-1539. DOI 10.1107/S0907444913010664 · PubMed
Other PDB entries of the same protein (UniProt P0C8P8 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 1E9W 1.02 Å, Structure of the macrocycle thiostrepton solved using the anomalous dispersive…
- 9CQ0 1.5 Å, Event-based electron counting microED structure of thiostrepton from a single crystal
- 6MXF 1.91 Å, MicroED structure of thiostrepton at 1.9 A resolution
- 5D8H 2.8 Å, Crystal structure of the base of the ribosomal P stalk from methanococcus jannaschii…
- 3CF5 3.3 Å, Thiopeptide antibiotic Thiostrepton bound to the large ribosomal subunit of Deinococcus…
- 1OLN Model for thiostrepton antibiotic binding to L11 substrate from 50S ribosomal RNA
- 2JQ7 Model for thiostrepton binding to the ribosomal L11-RNA
- 2L2W Thiostrepton
- 2L2X Thiostrepton, oxidized at CA-CB bond of residue 9
- 2L2Y Thiostrepton, epimer form of residue 9
- 2L2Z Thiostrepton, reduced at N-CA bond of residue 14
Browse structure collections
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