4PAS: PDB entry 4PAS

Heterodimeric coiled-coil structure of human GABA(B) receptor. Determined by X-ray diffraction at 1.62 Å resolution. Released 7 May 2014.

Method: X-ray diffraction
Resolution: 1.62 Å
Organism: Homo sapiens
Chains: 2
Atoms: 689
Mol. weight: 9.74 kDa
Released: 7 May 2014

Explore 4PAS in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

4PAS contains 2 α-helices and 0 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	768-800	33

Chain B: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	780-816	37

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Gamma-aminobutyric acid type B receptor subunit 1	A	protein	41	Homo sapiens	Q9UBS5 (AlphaFold model)
Gamma-aminobutyric acid type B receptor subunit 2	B	protein	41	Homo sapiens	O75899 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>4PAS_1 Gamma-aminobutyric acid type B receptor subunit 1 (chains A)
STNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSR

Sequence of entity 2 (B), FASTA

>4PAS_2 Gamma-aminobutyric acid type B receptor subunit 2 (chains B)
SVNQASTSRLEGLQSENHHLRMKITELDKDLEEVTMQLQDT

Primary citation

Heterodimeric coiled-coil interactions of human GABAB receptor. Burmakina, S., Geng, Y., Chen, Y. et al. Proc Natl Acad Sci U S A (2014) 111:6958-6963. DOI 10.1073/pnas.1400081111 · PubMed

Other PDB entries of the same protein (UniProt Q9UBS5 (AlphaFold model), which also has an AlphaFold model), best resolution first:

4MS4 1.9 Å, Crystal structure of the extracellular domain of human GABA(B) receptor bound to the…
4MR7 2.15 Å, Crystal structure of the extracellular domain of human GABA(B) receptor bound to the…
4MR8 2.15 Å, Crystal structure of the extracellular domain of human GABA(B) receptor bound to the…
4MQF 2.22 Å, Crystal structure of the extracellular domain of human GABA(B) receptor bound to the…
4MS1 2.25 Å, Crystal structure of the extracellular domain of human GABA(B) receptor bound to the…
4MQE 2.35 Å, Crystal structure of the extracellular domain of human GABA(B) receptor in the apo form
4MR9 2.35 Å, Crystal structure of the extracellular domain of human GABA(B) receptor bound to the…
4MS3 2.5 Å, Crystal structure of the extracellular domain of human GABA(B) receptor bound to the…
4MRM 2.86 Å, Crystal structure of the extracellular domain of human GABA(B) receptor bound to the…
7C7S 2.9 Å, Cryo-EM structure of the CGP54626-bound human GABA(B) receptor in inactive state.
7C7Q 3.0 Å, Cryo-EM structure of the baclofen/BHFF-bound human GABA(B) receptor in active state
6W2Y 3.2 Å, CryoEM Structure of GABAB1b Homodimer

Browse structure collections

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