5JJZ: Chromodomain Y-like protein 2

Chromo domain of human Chromodomain Protein, Y-Like 2. Determined by X-ray diffraction at 2.0 Å resolution. Released 25 May 2016.

Method: X-ray diffraction
Resolution: 2.0 Å
Organism: Homo sapiens
Chains: 2
Atoms: 533
Mol. weight: 11.55 kDa
Released: 25 May 2016

Explore 5JJZ in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

5JJZ contains 3 α-helices and 5 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 3 helices, 5 β-strands

Element	Residues	Length	Sheet
β-strand	-3-0	4	1
α-helix	1	1
β-strand	6-17	12	1
β-strand	23-29	7	1
α-helix	34-36	3
β-strand	38-41	4	1
α-helix	42-44	3
β-strand	45-47	3	1

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Chromodomain Y-like protein 2	A	protein	83	Homo sapiens	Q8N8U2 (AlphaFold model)
Lys-lys-lys-ala-arg-mly-ser-ala-gly-ala-ala-lys-tyr	B	protein	13	Homo sapiens	P10412 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>5JJZ_1 Chromodomain Y-like protein 2 (chains A)
MHHHHHHSSGRENLYFQGASGDLYEVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEH
HLLHCEEFIDEFNGLHMSKDKRI

Sequence of entity 2 (B), FASTA

>5JJZ_2 LYS-LYS-LYS-ALA-ARG-MLY-SER-ALA-GLY-ALA-ALA-LYS-TYR (chains B)
KKKARKSAGAAKY

Primary citation

The crystal structure of CDYL2 domain of human CDYL2 protein. WU, H., DONG, A., ZENG, H. et al. To be published.

Other PDB entries of the same protein (UniProt Q8N8U2 (AlphaFold model), which also has an AlphaFold model), best resolution first:

8SP6 1.45 Å, Complex structure of CDYL2 with an antagonist
4HAE 2.0 Å, Crystal structure of the CDYL2-chromodomain
6V2D 2.1 Å, Crystal Structure of chromodomain of CDYL2 in complex with inhibitor UNC3866
6V2H 2.6 Å, Crystal structure of CDYL2 in complex with H3tK27me3
6V3N 2.7 Å, Crystal structure of CDYL2 in complex with H3K27me3
6V8W 2.8 Å, CDYL2 chromodomain in complex with a synthetic peptide
2MJ8 Solution structure of CDYL2 chromodomain

Browse structure collections

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