5OJS: SAGA and NuA4 coactivator subunit Tra1

Cryo-EM structure of the SAGA and NuA4 coactivator subunit Tra1. Determined by electron microscopy at 3.7 Å resolution. Released 9 Aug 2017.

Method
Electron microscopy
Resolution
3.7 Å
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Chains
1
Atoms
28,407
Mol. weight
436.53 kDa
Released
9 Aug 2017

Explore 5OJS in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

5OJS contains 204 α-helices and 18 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain T: 204 helices, 18 β-strands

ElementResiduesLengthSheet
α-helix4-74
α-helix10-134
α-helix20-256
α-helix30-345
α-helix44-5815
α-helix69-735
α-helix74-8310
α-helix93-997
α-helix117-13014
α-helix142-15716
α-helix218-2203
α-helix232-2398
α-helix249-2535
α-helix293-30816
α-helix325-33410
α-helix342-35615
α-helix363-3675
α-helix375-3784
α-helix388-40215
α-helix408-42316
α-helix430-44112
α-helix443-45210
α-helix454-4563
α-helix458-49639
α-helix502-5054
α-helix512-52110
α-helix564-5663
α-helix573-5753
α-helix579-60022
α-helix601-6044
α-helix605-6073
α-helix608-6114
α-helix616-6183
α-helix628-64215
α-helix643-6475
α-helix677-68913
α-helix699-71315
α-helix720-7278
α-helix733-74614
α-helix756-77015
α-helix781-7833
α-helix789-80012
α-helix806-81611
α-helix824-8263
α-helix832-8409
α-helix856-8638
α-helix880-88910
α-helix894-9029
α-helix918-9203
α-helix921-93111
α-helix941-95111
β-strand97911
β-strand98212
β-strand99011
α-helix999-10057
α-helix1011-102818
α-helix1030-10323
α-helix1042-10476
α-helix1069-108921
α-helix1096-110914
α-helix1113-11208
α-helix1145-11473
α-helix1160-117819
α-helix1184-11874
α-helix1189-119911
α-helix1200-12023
α-helix1207-122014
α-helix1229-12324
α-helix1234-124613
α-helix1261-127010
α-helix1284-129310
α-helix1302-131312
α-helix1335-13395
α-helix1347-13548
α-helix1356-13616
α-helix1373-138311
α-helix1404-142421
α-helix1437-144610
α-helix1447-14493
α-helix1453-146614
α-helix1477-14804
α-helix1483-14875
α-helix1498-15069
α-helix1518-152811
α-helix1532-15365
α-helix1547-155610
α-helix1571-158313
α-helix1594-16007
α-helix1605-16139
α-helix1618-162811
α-helix1640-16423
α-helix1644-165310
α-helix1663-167816
α-helix1693-170816
α-helix1716-173318
α-helix1742-17498
α-helix1763-17686
α-helix1779-179012
α-helix1797-181620
α-helix1834-18418
α-helix1859-187416
α-helix1880-189011
α-helix1892-18954
α-helix1902-191211
α-helix1923-19286
α-helix1939-195517
α-helix1965-197612
α-helix1981-19877
α-helix1988-19903
α-helix2002-201312
α-helix2025-204117
α-helix2091-210616
α-helix2116-212712
α-helix2141-21444
α-helix2158-217316
α-helix2184-21918
α-helix2197-21993
α-helix2204-221714
α-helix2230-224314
α-helix2250-22523
α-helix2254-226411
α-helix2276-228611
α-helix2290-22934
α-helix2303-232018
α-helix2329-234113
α-helix2347-236014
α-helix2369-23768
α-helix2377-23804
α-helix2381-23855
α-helix2391-240313
α-helix2429-244012
α-helix2448-24558
α-helix2469-24779
β-strand248012
α-helix24931
α-helix2495-24962
α-helix2499-25013
α-helix2519-253315
α-helix2538-25425
α-helix2546-25494
α-helix2555-256713
α-helix2568-25703
α-helix2576-258712
α-helix2605-26117
α-helix2623-26264
α-helix2637-26415
α-helix2643-26453
α-helix2652-266918
α-helix2673-26808
α-helix2686-269510
α-helix2700-271314
α-helix2721-27233
α-helix2725-274016
α-helix2745-27473
α-helix2749-27524
α-helix2755-27584
α-helix2777-27804
α-helix2789-280517
α-helix2813-28153
α-helix2818-283013
α-helix2838-285821
α-helix2860-28634
α-helix2876-28827
α-helix2883-28853
α-helix2895-291420
α-helix2944-295613
α-helix2960-29656
α-helix2980-299011
α-helix2991-29933
α-helix2996-30005
α-helix3016-30183
α-helix3020-303213
α-helix3038-305013
α-helix3055-306814
α-helix3076-30783
α-helix3079-30868
α-helix3098-310710
α-helix3116-31227
α-helix3134-31363
α-helix3137-31415
α-helix3152-316110
α-helix3165-318117
α-helix3203-321715
α-helix3220-323617
α-helix3243-326018
α-helix3274-32829
α-helix3283-32864
α-helix3293-32975
α-helix3309-332416
β-strand3331-333223
α-helix3334-33374
α-helix33521
β-strand335314
α-helix33541
α-helix3368-33692
β-strand337014
β-strand3371-337445
β-strand3378-337923
β-strand3381-338226
β-strand3387-338826
β-strand3389-339575
β-strand3400-340675
α-helix3413-342210
α-helix3427-34326
α-helix3445-34473
β-strand3449-345025
β-strand3456-345835
β-strand346617
α-helix3468-347710
α-helix3483-349513
α-helix3507-352014
α-helix3526-35316
α-helix3539-356022
β-strand3572-357437
β-strand3581-358337
α-helix3626-36327
α-helix3636-36394
α-helix3641-365212
α-helix3658-367720
α-helix3687-370216
α-helix3718-372710
α-helix3730-37345

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Transcription-associated protein 1Tprotein3767Saccharomyces cerevisiae (strain ATCC 204508 / S288c)P38811
Sequence of entity 1 (T), FASTA
>5OJS_1 Transcription-associated protein 1 (chains T)
MDYKDHDGDYKDHDIDYKDDDDKMSLTEQIEQFASRFRDDDATLQSRYSTLSELYDIMEL
LNSPEDYHFFLQAVIPLLLNQLKEVPISYDAHSPEQKLRNSMLDIFNRCLMNQTFQPYAM
EVLEFLLSVLPKENEENGILCMKVLTTLFKSFKSILQDKLDSFIRIIIQIYKNTPNLINQ
TFYEAGKAEQGDLDSPKEPQADELLDEFSKNDEEKDFPSKQSSTEPRFENSTSSNGLRSS
MFSFKILSECPITMVTLYSSYKQLTSTSLPEFTPLIMNLLNIQIKQQQEAREQAESRGEH
FTSISTEIINRPAYCDFILAQIKATSFLAYVFIRGYAPEFLQDYVNFVPDLIIRLLQDCP
SELSSARKELLHATRHILSTNYKKLFLPKLDYLFDERILIGNGFTMHETLRPLAYSTVAD
FIHNIRSELQLSEIEKTIKIYTGYLLDESLALTVQIMSAKLLLNLVERILKLGKENPQEA
PRAKKLLMIIIDSYMNRFKTLNRQYDTIMKYYGRYETHKKEKAEKLKNSIQDNDKESEEF
MRKVLEPSDDDHLMPQPKKEDINDSPDVEMTESDKVVKNDVEMFDIKNYAPILLLPTPTN
DPIKDAFYLYRTLMSFLKTIIHDLKVFNPPPNEYTVANPKLWASVSRVFSYEEVIVFKDL
FHECIIGLKFFKDHNEKLSPETTKKHFDISMPSLPVSATKDARELMDYLAFMFMQMDNAT
FNEIIEQELPFVYERMLEDSGLLHVAQSFLTSEITSPNFAGILLRFLKGKLKDLGNVDFN
TSNVLIRLFKLSFMSVNLFPNINEVVLLPHLNDLILNSLKYSTTAEEPLVYFYLIRTLFR
SIGGGRFENLYRSIKPILQVLLQSLNQMILTARLPHERELYVELCITVPVRLSVLAPYLP
FLMKPLVFALQQYPDLVSQGLRTLELCIDNLTAEYFDPIIEPVIDDVSKALFNLLQPQPF
NHAISHNVVRILGKLGGRNRQFLKPPTDLTEKTELDIDAIADFKINGMPEDVPLSVTPGI
QSALNILQSYKSDIHYRKSAYKYLTCVLLLMTKSSAEFPTNYTELLKTAVNSIKLERIGI
EKNFDLEPTVNKRDYSNQENLFLRLLESVFYATSIKELKDDAMDLLNNLLDHFCLLQVNT
TLLNKRNYNGTFNIDLKNPNFMLDSSLILDAIPFALSYYIPEVREVGVLAYKRIYEKSCL
IYGEELALSHSFIPELAKQFIHLCYDETYYNKRGGVLGIKVLIDNVKSSSVFLKKYQYNL
ANGLLFVLKDTQSEAPSAITDSAEKLLIDLLSITFADVKEEDLGNKVLENTLTDIVCELS
NANPKVRNACQKSLHTISNLTGIPIVKLMDHSKQFLLSPIFAKPLRALPFTMQIGNVDAI
TFCLSLPNTFLTFNEELFRLLQESIVLADAEDESLSTNIQKTTEYSTSEQLVQLRIACIK
LLAIALKNEEFATAQQGNIRIRILAVFFKTMLKTSPEIINTTYEALKGSLAENSKLPKEL
LQNGLKPLLMNLSDHQKLTVPGLDALSKLLELLIAYFKVEIGRKLLDHLTAWCRVEVLDT
LFGQDLAEQMPTKIIVSIINIFHLLPPQADMFLNDLLLKVMLLERKLRLQLDSPFRTPLA
RYLNRFHNPVTEYFKKNMTLRQLVLFMCNIVQRPEAKELAEDFEKELDNFYDFYISNIPK
NQVRVVSFFTNMVDLFNTMVITNGDEWLKKKGNMILKLKDMLNLTLKTIKENSFYIDHLQ
LNQSIAKFQALYLRFTELSERDQNPLLLDFIDFSFSNGIKASYSLKKFIFHNIIASSNKE
KQNNFINDATLFVLSDKCLDARIFVLKNVINSTLIYEVATSGSLKSYLVEDKKPKWLELL
HNKIWKNSNAILAYDVLDHHDLFRFELLQLSAIFIKADPEIIAEIKKDIIKFCWNFIKLE
DTLIKQSAYLVTSYFISKFDFPIKVVTQVFVALLRSSHVEARYLVKQSLDVLTPVLHERM
NAAGTPDTWINWVKRVMVENSSSQNNILYQFLISHPDLFFNSRDLFISNIIHHMNKITFM
SNSNSDSHTLAIDLASLILYWENKTLEITNVNNTKTDSDGDVVMSDSKSDINPVEADTTA
IIVDANNNSPISLHLREACTAFLIRYVCASNHRAIETELGLRAINILSELISDKHWTNVN
VKLVYFEKFLIFQDLDSENILYYCMNALDVLYVFFKNKTKEWIMENLPTIQNLLEKCIKS
DHHDVQEALQKVLQVIMKAIKAQGVSVIIEEESPGKTFIQMLTSVITQDLQETSSVTAGV
TLAWVLFMNFPDNIVPLLTPLMKTFSKLCKDHLSISQPKDAMALEEARITTKLLEKVLYI
LSLKVSLLGDSRRPFLSTVALLIDHSMDQNFLRKIVNMSRSWIFNTEIFPTVKEKAAILT
KMLAFEIRGEPSLSKLFYEIVLKLFDQEHFNNTEITVRMEQPFLVGTRVEDIGIRKRFMT
ILDNSLERDIKERLYYVIRDQNWEFIADYPWLNQALQLLYGSFNREKELSLKNIYCLSPP
SILQEYLPENAEMVTEVNDLELSNFVKGHIASMQGLCRIISSDFIDSLIEIFYQDPKAIH
RAWVTLFPQVYKSIPKNEKYGFVRSIITLLSKPYHTRQISSRTNVINMLLDSISKIESLE
LPPHLVKYLAISYNAWYQSINILESIQSNTSIDNTKIIEANEDALLELYVNLQEEDMFYG
LWRRRAKYTETNIGLSYEQIGLWDKAQQLYEVAQVKARSGALPYSQSEYALWEDNWIQCA
EKLQHWDVLTELAKHEGFTDLLLECGWRVADWNSDRDALEQSVKSVMDVPTPRRQMFKTF
LALQNFAESRKGDQEVRKLCDEGIQLSLIKWVSLPIRYTPAHKWLLHGFQQYMEFLEATQ
IYANLHTTTVQNLDSKAQEIKRILQAWRDRLPNTWDDVNMWNDLVTWRQHAFQVINNAYL
PLIPALQQSNSNSNINTHAYRGYHEIAWVINRFAHVARKHNMPDVCISQLARIYTLPNIE
IQEAFLKLREQAKCHYQNMNELTTGLDVISNTNLVYFGTVQKAEFFTLKGMFLSKLRAYE
EANQAFATAVQIDLNLAKAWAQWGFFNDRRLSEEPNNISFASNAISCYLQAAGLYKNSKI
RELLCRILWLISIDDASGMLTNAFDSFRGEIPVWYWITFIPQLLTSLSHKEANMVRHILI
RIAKSYPQALHFQLRTTKEDFAVIQRQTMAVMGDKPDTNDRNGRRQPWEYLQELNNILKT
AYPLLALSLESLVAQINDRFKSTTDEDLFRLINVLLIDGTLNYNRLPFPRKNPKLPENTE
KNLVKFSTTLLAPYIRPKFNADFIDNKPDYETYIKRLRYWRRRLENKLDRASKKENLEVL
CPHLSNFHHQKFEDIEIPGQYLLNKDNNVHFIKIARFLPTVDFVRGTHSSYRRLMIRGHD
GSVHSFAVQYPAVRHSRREERMFQLYRLFNKSLSKNVETRRRSIQFNLPIAIPLSPQVRI
MNDSVSFTTLHEIHNEFCKKKGFDPDDIQDFMADKLNAAHDDALPAPDMTILKVEIFNSI
QTMFVPSNVLKDHFTSLFTQFEDFWLFRKQFASQYSSFVFMSYMMMINNRTPHKIHVDKT
SGNVFTLEMLPSRFPYERVKPLLKNHDLSLPPDSPIFHNNEPVPFRLTPNIQSLIGDSAL
EGIFAVNLFTISRALIEPDNELNTYLALFIRDEIISWFSNLHRPIIENPQLREMVQTNVD
LIIRKVAQLGHLNSTPTVTTQFILDCIGSAVSPRNLARTDVNFMPWF

Primary citation

Cryo-EM structure of the SAGA and NuA4 coactivator subunit Tra1 at 3.7 angstrom resolution. Diaz-Santin, L.M., Lukoyanova, N., Aciyan, E. et al. Elife (2017) 6. DOI 10.7554/eLife.28384 · PubMed

Other PDB entries of the same protein (UniProt P38811), best resolution first:

Browse structure collections

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