6EU2: Apo RNA Polymerase III - open conformation

Name: PDB 6EU2: Apo RNA Polymerase III - open conformation (oPOL3)
Published: 2018-01-17
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: transcription

Apo RNA Polymerase III - open conformation (oPOL3). Determined by electron microscopy at 3.4 Å resolution. Released 17 Jan 2018.

Method: Electron microscopy
Resolution: 3.4 Å
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Chains: 17
Atoms: 38,329
Mol. weight: 694.53 kDa
Ligands: ZN, MG
Released: 17 Jan 2018

Explore 6EU2 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6EU2 contains 192 α-helices and 240 β-strands across 17 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 57 helices, 54 β-strands

Element	Residues	Length	Sheet
β-strand	3-4	2	1
β-strand	11-19	9	2
α-helix	23-29	7
β-strand	30-33	4	3
β-strand	81	1	3
β-strand	82	1	4
β-strand	83	1	3
β-strand	85-90	6	5
α-helix	96-103	8
α-helix	119-127	9
α-helix	134-147	14
α-helix	148-150	3
β-strand	153	1	6
β-strand	160	1	6
β-strand	163-166	4	7
β-strand	178-181	4	7
α-helix	192-207	16
β-strand	220-221	2	7
α-helix	224-230	7
α-helix	253-256	4
β-strand	258-260	3	5
β-strand	263	1	4
α-helix	264-265	2
α-helix	285-302	18
α-helix	309-326	18
β-strand	371-372	2	8
β-strand	376-383	8	9
β-strand	391-395	5	9
β-strand	404-407	4	10
α-helix	413-422	10
β-strand	430-434	5	10
β-strand	441-443	3	10
α-helix	451-455	5
β-strand	461-464	4	10
α-helix	465-466	2
β-strand	471-475	5	9
α-helix	482-484	3
β-strand	485-493	9	9
β-strand	498-500	3	9
α-helix	505-508	4
β-strand	516-520	5	9
α-helix	529-532	4
α-helix	555-564	10
β-strand	570-571	2	11
α-helix	576-582	7
α-helix	592-595	4
β-strand	597	1	12
β-strand	603	1	12
β-strand	604-605	2	11
α-helix	607-614	8
β-strand	627-628	2	13
β-strand	652-654	3	13
β-strand	659-661	3	13
α-helix	677-684	8
α-helix	686-708	23
α-helix	723-739	17
α-helix	742-745	4
α-helix	760-776	17
α-helix	780-783	4
α-helix	790-796	7
α-helix	803-809	7
β-strand	818	1	14
β-strand	821	1	14
α-helix	858-876	19
α-helix	878-881	4
α-helix	884-889	6
β-strand	897-898	2	15
β-strand	904-905	2	15
β-strand	911-913	3	15
α-helix	916-918	3
β-strand	921	1	16
α-helix	935-945	11
β-strand	954	1	17
α-helix	959-962	4
α-helix	969-972	4
β-strand	977	1	18
β-strand	983	1	18
α-helix	984-985	2
α-helix	999-1024	26
α-helix	1029-1030	2
α-helix	1050-1059	10
β-strand	1062	1	17
α-helix	1064-1079	16
β-strand	1082	1	16
α-helix	1083-1084	2
α-helix	1089-1101	13
β-strand	1109	1	19
β-strand	1119	1	19
α-helix	1123-1130	8
β-strand	1141-1142	2	20
α-helix	1151-1159	9
α-helix	1165-1168	4
β-strand	1173	1	21
β-strand	1176-1178	3	22
β-strand	1181-1183	3	22
β-strand	1186	1	21
α-helix	1191-1195	5
α-helix	1202-1210	9
α-helix	1256-1265	10
β-strand	1281-1285	5	20
β-strand	1291-1295	5	20
β-strand	1315-1316	2	20
α-helix	1319-1325	7
α-helix	1329-1344	16
α-helix	1353-1361	9
α-helix	1395-1401	7
α-helix	1414-1417	4
α-helix	1419-1421	3
α-helix	1424-1426	3
β-strand	1429-1432	4	23
α-helix	1450-1454	5

Chain B: 45 helices, 75 β-strands

Element	Residues	Length	Sheet
α-helix	43-46	4
α-helix	47-54	8
α-helix	59-67	9
α-helix	68-72	5
α-helix	73-77	5
β-strand	82	1	24
β-strand	94	1	24
β-strand	95-100	6	25
α-helix	117-120	4
β-strand	126-135	10	25
β-strand	143-153	11	25
α-helix	154-155	2
α-helix	168-173	6
β-strand	185-187	3	26
β-strand	190-194	5	26
α-helix	195	1
β-strand	196-200	5	27
α-helix	201	1
β-strand	205-208	4	28
β-strand	216-219	4	28
β-strand	220	1	29
β-strand	229	1	29
β-strand	231	1	30
β-strand	234	1	31
β-strand	240	1	31
β-strand	243	1	30
β-strand	247	1	32
α-helix	253-259	7
α-helix	280-288	9
α-helix	301-307	7
β-strand	309	1	32
α-helix	317-319	3
α-helix	323-328	6
α-helix	345-361	17
α-helix	372-374	3
β-strand	375-378	4	27
α-helix	380-403	24
α-helix	413-414	2
α-helix	428-438	11
β-strand	455-457	3	26
α-helix	458-459	2
α-helix	463-469	7
β-strand	472-474	3	27
α-helix	489-490	2
α-helix	491-493	3
β-strand	497	1	33
β-strand	511-513	3	27
β-strand	514	1	33
β-strand	519-520	2	34
α-helix	527-536	10
α-helix	538-540	3
α-helix	541-543	3
α-helix	553	1
β-strand	554-557	4	35
β-strand	560-561	2	35
α-helix	568-582	15
β-strand	589-593	5	35
β-strand	598-602	5	35
β-strand	608-609	2	34
β-strand	610-614	5	36
β-strand	615	1	37
β-strand	620	1	37
α-helix	624-630	7
β-strand	646-649	4	36
α-helix	654-656	3
β-strand	659-660	2	36
β-strand	672-673	2	36
α-helix	677-679	3
α-helix	685-687	3
β-strand	694	1	38
α-helix	697-705	9
β-strand	724-728	5	39
β-strand	737	1	40
β-strand	753-759	7	41
β-strand	770-774	5	41
β-strand	785-795	11	39
β-strand	798	1	42
β-strand	802	1	42
β-strand	806	1	43
β-strand	812	1	44
β-strand	815	1	44
α-helix	819-821	3
β-strand	824	1	45
β-strand	829	1	46
β-strand	830	1	45
α-helix	831	1
β-strand	832	1	47
β-strand	835-836	2	39
β-strand	841-843	3	46
β-strand	845	1	43
β-strand	846-848	3	48
β-strand	866-868	3	48
β-strand	871-872	2	46
β-strand	879-887	9	39
β-strand	894-904	11	39
β-strand	911-913	3	41
β-strand	920-926	7	41
β-strand	942-944	3	41
α-helix	946-948	3
β-strand	954	1	38
α-helix	956-969	14
β-strand	975	1	40
α-helix	984-992	9
β-strand	1001-1002	2	41
β-strand	1005	1	49
β-strand	1012	1	49
α-helix	1013	1
β-strand	1017-1026	10	41
β-strand	1036-1038	3	9
β-strand	1046	1	9
β-strand	1061-1062	2	8
α-helix	1064-1073	10
α-helix	1077-1079	3
α-helix	1080-1085	6
α-helix	1086-1088	3
β-strand	1089-1095	7	50
β-strand	1101	1	50
β-strand	1116-1122	7	50
α-helix	1123-1134	12
β-strand	1138-1145	8	2

Chain C: 12 helices, 19 β-strands

Element	Residues	Length	Sheet
β-strand	7	1	51
β-strand	12	1	51
α-helix	33-39	7
β-strand	41-47	7	52
β-strand	51-57	7	52
α-helix	61-70	10
β-strand	77-86	10	53
α-helix	96-102	7
α-helix	105	1
β-strand	106-107	2	54
α-helix	110-112	3
α-helix	122-125	4
β-strand	132-139	8	53
β-strand	141	1	55
β-strand	158	1	55
β-strand	161	1	56
α-helix	164-166	3
β-strand	168-170	3	53
β-strand	185-186	2	54
β-strand	195	1	56
β-strand	201-211	11	53
α-helix	217-219	3
β-strand	222-235	14	52
α-helix	242-250	9
β-strand	256-257	2	57
β-strand	266-267	2	57
α-helix	270-272	3
α-helix	278-280	3
β-strand	289-304	16	52
α-helix	310-326	17
β-strand	334	1	58

Chain D: 7 helices, 1 β-strand

Element	Residues	Length	Sheet
β-strand	3-5	3	59
α-helix	13-23	11
α-helix	56-65	10
α-helix	66-68	3
α-helix	101-112	12
α-helix	118-126	9
α-helix	133-137	5
α-helix	147-160	14

Chain E: 11 helices, 11 β-strands

Element	Residues	Length	Sheet
α-helix	3-5	3
α-helix	8-25	18
β-strand	28	1	60
α-helix	40-46	7
β-strand	47	1	61
α-helix	52	1
β-strand	53	1	61
α-helix	54	1
β-strand	64	1	60
α-helix	68-71	4
β-strand	81	1	62
α-helix	91-102	12
β-strand	107-110	4	62
α-helix	118-120	3
β-strand	131-134	4	62
β-strand	152-155	4	63
α-helix	158-167	10
α-helix	176	1
β-strand	177-178	2	63
α-helix	185-188	4
β-strand	195-201	7	63
β-strand	207-214	8	63

Chain F: 6 helices, 6 β-strands

Element	Residues	Length	Sheet
β-strand	72	1	64
α-helix	73-74	2
α-helix	76-78	3
β-strand	84	1	65
α-helix	85-86	2
α-helix	88-101	14
α-helix	105-107	3
α-helix	117-127	11
β-strand	132-135	4	23
β-strand	142	1	64
β-strand	147	1	23
β-strand	152	1	65

Chain G: 5 helices, 21 β-strands

Element	Residues	Length	Sheet
β-strand	3-4	2	66
β-strand	6-7	2	59
β-strand	10-13	4	23
α-helix	15-17	3
α-helix	22-31	10
β-strand	37-38	2	1
β-strand	39	1	67
β-strand	43	1	67
β-strand	44-45	2	66
β-strand	51-52	2	59
β-strand	57-58	2	23
β-strand	66-69	4	23
β-strand	71-72	2	59
β-strand	75-77	3	66
β-strand	84-86	3	68
β-strand	88-91	4	69
β-strand	97-100	4	69
β-strand	101	1	70
β-strand	105	1	70
β-strand	109-110	2	69
α-helix	112-114	3
α-helix	128-130	3
β-strand	147-149	3	68
β-strand	153-154	2	71
α-helix	165-167	3
β-strand	195-196	2	71

Chain H: 2 helices, 11 β-strands

Element	Residues	Length	Sheet
β-strand	4-16	13	72
β-strand	23-30	8	72
β-strand	38-43	6	72
β-strand	54-60	7	72
α-helix	81-83	3
α-helix	89-91	3
β-strand	95-96	2	72
β-strand	97	1	12
β-strand	100-105	6	72
β-strand	113-118	6	72
β-strand	121-126	6	72
β-strand	138	1	72
β-strand	142-145	4	72

9 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
DNA-directed RNA polymerase III subunit RPC1	A	protein	1460	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P04051 (AlphaFold model)
DNA-directed RNA polymerase III subunit RPC2	B	protein	1149	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P22276 (AlphaFold model)
DNA-directed RNA polymerases I and III subunit RPAC1	C	protein	335	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P07703 (AlphaFold model)
DNA-directed RNA polymerase III subunit RPC9	D	protein	161	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P47076 (AlphaFold model)
DNA-directed RNA polymerases I, II, and III subunit RPABC1	E	protein	215	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P20434
DNA-directed RNA polymerases I, II, and III subunit RPABC2	F	protein	155	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P20435
DNA-directed RNA polymerase III subunit RPC8	G	protein	212	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P35718
DNA-directed RNA polymerases I, II, and III subunit RPABC3	H	protein	146	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P20436
DNA-directed RNA polymerase III subunit RPC10	I	protein	110	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	Q04307
DNA-directed RNA polymerases I, II, and III subunit RPABC5	J	protein	70	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P22139
DNA-directed RNA polymerases I and III subunit RPAC2	K	protein	142	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P28000
DNA-directed RNA polymerases I, II, and III subunit RPABC4	L	protein	70	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P40422

5 more molecules are not listed.

Sequence of entity 1 (A), FASTA

>6EU2_1 DNA-directed RNA polymerase III subunit RPC1 (chains A)
MKEVVVSETPKRIKGLEFSALSAADIVAQSEVEVSTRDLFDLEKDRAPKANGALDPKMGV
SSSSLECATCHGNLASCHGHFGHLKLALPVFHIGYFKATIQILQGICKNCSAILLSETDK
RQFLHELRRPGVDNLRRMGILKKILDQCKKQRRCLHCGALNGVVKKAAAGAGSAALKIIH
DTFRWVGKKSAPEKDIWVGEWKEVLAHNPELERYVKRCMDDLNPLKTLNLFKQIKSADCE
LLGIDATVPSGRPETYIWRYLPAPPVCIRPSVMMQDSPASNEDDLTVKLTEIVWTSSLIK
AGLDKGISINNMMEHWDYLQLTVAMYINSDSVNPAMLPGSSNGGGKVKPIRGFCQRLKGK
QGRFRGNLSGKRVDFSGRTVISPDPNLSIDEVAVPDRVAKVLTYPEKVTRYNRHKLQELI
VNGPNVHPGANYLLKRNEDARRNLRYGDRMKLAKNLQIGDVVERHLEDGDVVLFNRQPSL
HRLSILSHYAKIRPWRTFRLNECVCTPYNADFDGDEMNLHVPQTEEARAEAINLMGVKNN
LLTPKSGEPIIAATQDFITGSYLISHKDSFYDRATLTQLLSMMSDGIEHFDIPPPAIMKP
YYLWTGKQVFSLLIKPNHNSPVVINLDAKNKVFVPPKSKSLPNEMSQNDGFVIIRGSQIL
SGVMDKSVLGDGKKHSVFYTILRDYGPQEAANAMNRMAKLCARFLGNRGFSIGINDVTPA
DDLKQKKEELVEIAYHKCDELITLFNKGELETQPGCNEEQTLEAKIGGLLSKVREEVGDV
CINELDNWNAPLIMATCGSKGSTLNVSQMVAVVGQQIISGNRVPDGFQDRSLPHFPKNSK
TPQSKGFVRNSFFSGLSPPEFLFHAISGREGLVDTAVKTAETGYMSRRLMKSLEDLSCQY
DNTVRTSANGIVQFTYGGDGLDPLEMEGNAQPVNFNRSWDHAYNITFNNQDKGLLPYAIM
ETANEILGPLEERLVRYDNSGCLVKREDLNKAEYVDQYDAERDFYHSLREYINGKATALA
NLRKSRGMLGLLEPPAKELQGIDPDETVPDNVKTSVSQLYRISEKSVRKFLEIALFKYRK
ARLEPGTAIGAIGAQSIGEPGTQMTLKTFHFAGVASMNVTLGVPRIKEIINASKVISTPI
INAVLVNDNDERAARVVKGRVEKTLLSDVAFYVQDVYKDNLSFIQVRIDLGTIDKLQLEL
TIEDIAVAITRASKLKIQASDVNIIGKDRIAINVFPEGYKAKSISTSAKEPSENDVFYRM
QQLRRALPDVVVKGLPDISRAVINIRDDGKRELLVEGYGLRDVMCTDGVIGSRTTTNHVL
EVFSVLGIEAARYSIIREINYTMSNHGMSVDPRHIQLLGDVMTYKGEVLGITRFGLSKMR
DSVLQLASFEKTTDHLFDAAFYMKKDAVEGVSECIILGQTMSIGTGSFKVVKGTNISEKD
LVPKRCLFESLSNEAALKAN

Sequence of entity 2 (B), FASTA

>6EU2_2 DNA-directed RNA polymerase III subunit RPC2 (chains B)
MVAATKRRKTHIHKHVKDEAFDDLLKPVYKGKKLTDEINTAQDKWHLLPAFLKVKGLVKQ
HLDSFNYFVDTDLKKIIKANQLILSDVDPEFYLKYVDIRVGKKSSSSTKDYLTPPHECRL
RDMTYSAPIYVDIEYTRGRNIIMHKDVEIGRMPIMLRSNKCILYDADESKMAKLNECPLD
PGGYFIVNGTEKVILVQEQLSKNRIIVEADEKKGIVQASVTSSTHERKSKTYVITKNGKI
YLKHNSIAEEIPIAIVLKACGILSDLEIMQLVCGNDSSYQDIFAVNLEESSKLDIYTQQQ
ALEYIGAKVKTMRRQKLTILQEGIEAIATTVIAHLTVEALDFREKALYIAMMTRRVVMAM
YNPKMIDDRDYVGNKRLELAGQLISLLFEDLFKKFNNDFKLSIDKVLKKPNRAMEYDALL
SINVHSNNITSGLNRAISTGNWSLKRFKMERAGVTHVLSRLSYISALGMMTRISSQFEKS
RKVSGPRALQPSQFGMLCTADTPEGEACGLVKNLALMTHITTDDEEEPIKKLCYVLGVED
ITLIDSASLHLNYGVYLNGTLIGSIRFPTKFVTQFRHLRRTGKVSEFISIYSNSHQMAVH
IATDGGRICRPLIIVSDGQSRVKDIHLRKLLDGELDFDDFLKLGLVEYLDVNEENDSYIA
LYEKDIVPSMTHLEIEPFTILGAVAGLIPYPHHNQSPRNTYQCAMGKQAIGAIAYNQFKR
IDTLLYLMTYPQQPMVKTKTIELIDYDKLPAGQNATVAVMSYSGYDIEDALVLNKSSIDR
GFGRCETRRKTTTVLKRYANHTQDIIGGMRVDENGDPIWQHQSLGPDGLGEVGMKVQSGQ
IYINKSVPTNSADAPNPNNVNVQTQYREAPVIYRGPEPSHIDQVMMSVSDNDQALIKVLL
RQNRRPELGDKFSSRHGQKGVCGIIVKQEDMPFNDQGIVPDIIMNPHGFPSRMTVGKMIE
LISGKAGVLNGTLEYGTCFGGSKLEDMSKILVDQGFNYSGKDMLYSGITGECLQAYIFFG
PIYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCVIAYGASQLLL
ERLMISSDAFEVDVCDKCGLMGYSGWCTTCKSAENIIKMTIPYAAKLLFQELLSMNIAPR
LRLEDIFQQ

Sequence of entity 3 (C), FASTA

>6EU2_3 DNA-directed RNA polymerases I and III subunit RPAC1 (chains C)
MSNIVGIEYNRVTNTTSTDFPGFSKDAENEWNVEKFKKDFEVNISSLDAREANFDLINID
TSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHRIGLVPLKVDPDMLTWVDSNL
PDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELYNNAHVYARDLKFEPQGRQSTTFA
DCPVVPADPDILLAKLRPGQEISLKAHCILGIGGDHAKFSPVSTASYRLLPQINILQPIK
GESARRFQKCFPPGVIGIDEGSDEAYVKDARKDTVSREVLRYEEFADKVKLGRVRNHFIF
NVESAGAMTPEEIFFKSVRILKNKAEYLKNCPITQ

Sequence of entity 4 (D), FASTA

>6EU2_4 DNA-directed RNA polymerase III subunit RPC9 (chains D)
MKVLEERNAFLSDYEVLKFLTDLEKKHLWDQKSLAALKKSRSKGKQNRPYNHPELQGITR
NVVNYLSINKNFINQEDEGEERESSGAKDAEKSGISKMSDESFAELMTKLNSFKLFKAEK
LQIVNQLPANMVHLYSIVEECDARFDEKTIEEMLEIISGYA

Sequence of entity 5 (E), FASTA

>6EU2_5 DNA-directed RNA polymerases I, II, and III subunit RPABC1 (chains E)
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSF
QANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSA
MKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQR
ADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM

Sequence of entity 6 (F), FASTA

>6EU2_6 DNA-directed RNA polymerases I, II, and III subunit RPABC2 (chains F)
MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVTGGNGPEDFQQ
HEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRI
AMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL

Sequence of entity 7 (G), FASTA

>6EU2_7 DNA-directed RNA polymerase III subunit RPC8 (chains G)
MFILSKIADLVRIPPDQFHRDTISAITHQLNNKFANKIIPNVGLCITIYDLLTVEEGQLK
PGDGSSYINVTFRAVVFKPFLGEIVTGWISKCTAEGIKVSLLGIFDDIFIPQNMLFEGCY
YTPEESAWIWPMDEETKLYFDVNEKIRFRIEREVFVDVKPKSPKERELEERAQLENEIEG
KNEETPQNEKPPAYALLGSCQTDGMGLVSWWE

Sequence of entity 8 (H), FASTA

>6EU2_8 DNA-directed RNA polymerases I, II, and III subunit RPABC3 (chains H)
MSNTLFDDIFQVSEVDPGRYNKVCRIEAASTTQDQCKLTLDINVELFPVAAQDSLTVTIA
SSLNLEDTPANDSSATRSWRPPQAGDRSLADDYDYVMYGTAYKFEEVSKDLIAVYYSFGG
LLMRLEGNYRNLNNLKQENAYLLIRR

Sequence of entity 9 (I), FASTA

>6EU2_9 DNA-directed RNA polymerase III subunit RPC10 (chains I)
MLSFCPSCNNMLLITSGDSGVYTLACRSCPYEFPIEGIEIYDRKKLPRKEVDDVLGGGWD
NVDQTKTQCPNYDTCGGESAYFFQLQIRSADEPMTTFYKCVNCGHRWKEN

Sequence of entity 10 (J), FASTA

>6EU2_10 DNA-directed RNA polymerases I, II, and III subunit RPABC5 (chains J)
MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKF
LRYNPLEKRD

Sequence of entity 11 (K), FASTA

>6EU2_11 DNA-directed RNA polymerases I and III subunit RPAC2 (chains K)
MTEDIEQKKTATEVTPQEPKHIQEEEEQDVDMTGDEEQEEEPDREKIKLLTQATSEDGTS
ASFQIVEEDHTLGNALRYVIMKNPDVEFCGYSIPHPSENLLNIRIQTYGETTAVDALQKG
LKDLMDLCDVVESKFTEKIKSM

Sequence of entity 12 (L), FASTA

>6EU2_12 DNA-directed RNA polymerases I, II, and III subunit RPABC4 (chains L)
MSREGFQIPTNLDAAAAGTSQARTATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKAR
TKRLVQFEAR

Ligands and cofactors

ID	Name	Formula	Copies
ZN	Zinc ion	Zn	6
MG	Magnesium ion	Mg	1

Primary citation

Structural basis of RNA polymerase III transcription initiation. Abascal-Palacios, G., Ramsay, E.P., Beuron, F. et al. Nature (2018) 553:301-306. DOI 10.1038/nature25441 · PubMed

Other PDB entries of the same protein (UniProt P04051 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7Z0H 2.6 Å, Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.6 A (focus subunit AC40).
7Z1O 2.7 Å, Structure of yeast RNA Polymerase III PTC + NTPs
7Z31 2.76 Å, Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11,…
7Z1L 2.8 Å, Structure of yeast RNA Polymerase III Pre-Termination Complex (PTC)
7Z30 2.9 Å, Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.9 A (focus subunit C11…
7Z2Z 3.07 Å, Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A
8BWS 3.2 Å, Structure of yeast RNA Polymerase III elongation complex at 3.3 A
6TUT 3.25 Å, Cryo-EM structure of the RNA Polymerase III-Maf1 complex
6EU3 3.3 Å, Apo RNA Polymerase III - closed conformation (cPOL3)
6EU1 3.4 Å, RNA Polymerase III - open DNA complex (OC-POL3).
7Z1M 3.4 Å, Structure of yeast RNA Polymerase III Elongation Complex (EC)
6F40 3.7 Å, RNA Polymerase III open complex

Browse structure collections

About this viewer

MolViewer shows 6EU2 directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.