7Z0H: Yeast RNA Polymerase III-Ty1 integrase complex

Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.6 A (focus subunit AC40). Determined by electron microscopy at 2.6 Å resolution. Released 5 Apr 2023.

Method: Electron microscopy
Resolution: 2.6 Å
Organism: Saccharomyces cerevisiae S288C
Chains: 19
Atoms: 40,665
Mol. weight: 763.74 kDa
Ligands: ZN, MG
Released: 5 Apr 2023

Explore 7Z0H in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7Z0H contains 243 α-helices and 276 β-strands across 17 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 80 helices, 60 β-strands

Element	Residues	Length	Sheet
β-strand	4	1	1
β-strand	11-17	7	2
α-helix	23-29	7
β-strand	32-33	2	3
α-helix	56-58	3
β-strand	82-90	9	3
α-helix	96-105	10
β-strand	106	1	4
β-strand	113	1	4
α-helix	121-127	7
α-helix	134-150	17
β-strand	166	1	5
β-strand	178-180	3	5
α-helix	192-205	14
α-helix	211-214	4
β-strand	220-222	3	5
α-helix	224-231	8
α-helix	236-238	3
α-helix	253-256	4
β-strand	258-263	6	3
α-helix	264-265	2
α-helix	270-271	2
β-strand	272	1	6
α-helix	280	1
β-strand	281	1	6
α-helix	284-305	22
α-helix	309-328	20
α-helix	353-357	5
α-helix	364-368	5
β-strand	371-373	3	7
β-strand	376-383	8	8
β-strand	391-395	5	8
α-helix	396-399	4
β-strand	403-407	5	9
α-helix	408	1
α-helix	413-422	10
β-strand	430-434	5	9
α-helix	441	1
β-strand	442-443	2	9
α-helix	449-454	6
β-strand	461-465	5	9
α-helix	466	1
β-strand	471-475	5	8
α-helix	482-484	3
β-strand	485-493	9	8
β-strand	498-500	3	8
α-helix	502-504	3
α-helix	505-508	4
β-strand	516-520	5	8
α-helix	525-534	10
β-strand	536	1	8
α-helix	538-540	3
β-strand	542	1	10
β-strand	549	1	10
α-helix	555-565	11
β-strand	570-571	2	11
α-helix	573-583	11
α-helix	592-595	4
β-strand	597-599	3	12
β-strand	603	1	12
β-strand	604-605	2	11
α-helix	606-614	9
β-strand	626-629	4	13
α-helix	634-635	2
β-strand	636	1	14
α-helix	643-645	3
β-strand	646	1	14
β-strand	651-655	5	13
β-strand	658-661	4	13
α-helix	666-669	4
α-helix	677-685	9
α-helix	687-708	22
α-helix	714-716	3
α-helix	718-720	3
α-helix	721-747	27
α-helix	758-783	26
α-helix	785-786	2
α-helix	790-797	8
α-helix	803-810	8
β-strand	813-815	3	15
β-strand	818	1	16
β-strand	821	1	16
β-strand	827	1	17
β-strand	830	1	17
α-helix	842-845	4
β-strand	847-848	2	15
α-helix	858-881	24
α-helix	885-893	9
β-strand	897-898	2	18
β-strand	904-905	2	18
β-strand	911-913	3	18
α-helix	916-918	3
β-strand	921	1	19
α-helix	923-925	3
α-helix	935-945	11
α-helix	952-955	4
α-helix	956-966	11
α-helix	969-973	5
β-strand	977	1	20
β-strand	983	1	20
α-helix	999-1025	27
α-helix	1034-1035	2
α-helix	1038-1041	4
α-helix	1052-1059	8
α-helix	1064-1081	18
β-strand	1082	1	19
α-helix	1083-1084	2
α-helix	1089-1098	10
α-helix	1100-1102	3
α-helix	1123-1131	9
β-strand	1141-1145	5	21
α-helix	1150-1154	5
α-helix	1155-1160	6
α-helix	1166-1170	5
β-strand	1173	1	22
β-strand	1176-1177	2	23
β-strand	1182-1183	2	23
β-strand	1184-1187	4	24
α-helix	1190-1195	6
α-helix	1203-1216	14
β-strand	1222-1224	3	24
β-strand	1229-1232	4	24
α-helix	1255-1266	12
α-helix	1267-1269	3
β-strand	1278-1285	8	21
β-strand	1291-1297	7	21
α-helix	1300-1305	6
β-strand	1309-1316	8	21
α-helix	1319-1325	7
α-helix	1328-1344	17
α-helix	1352-1363	12
α-helix	1373-1376	4
α-helix	1383-1389	7
α-helix	1392-1402	11
β-strand	1407	1	2
α-helix	1411-1416	6
α-helix	1419-1421	3
α-helix	1424-1426	3
β-strand	1429-1432	4	25
α-helix	1448-1454	7

Chain B: 57 helices, 87 β-strands

Element	Residues	Length	Sheet
α-helix	40-43	4
α-helix	44-46	3
α-helix	47-54	8
α-helix	60-67	8
α-helix	68-72	5
α-helix	73-79	7
β-strand	82-83	2	26
β-strand	93-100	8	26
α-helix	110-114	5
α-helix	115-121	7
β-strand	126-135	10	26
β-strand	147-153	7	26
α-helix	154-155	2
α-helix	169-173	5
β-strand	185-187	3	27
β-strand	190-194	5	27
β-strand	196-200	5	28
α-helix	201	1
β-strand	206-208	3	29
β-strand	216-218	3	29
β-strand	220-222	3	30
β-strand	227-229	3	30
β-strand	231	1	31
β-strand	233	1	29
β-strand	234	1	32
β-strand	240	1	32
β-strand	241-242	2	33
β-strand	243	1	31
β-strand	247	1	34
α-helix	250	1
β-strand	251-252	2	33
α-helix	253-259	7
α-helix	267-273	7
β-strand	276	1	35
α-helix	277-283	7
α-helix	285-293	9
α-helix	298-307	10
β-strand	309	1	34
α-helix	317-319	3
α-helix	324-330	7
α-helix	343-361	19
α-helix	372-374	3
β-strand	375-378	4	28
α-helix	380-407	28
α-helix	420-425	6
α-helix	427-439	13
β-strand	442-444	3	36
β-strand	449-451	3	36
β-strand	455-457	3	27
α-helix	458-459	2
α-helix	463-469	7
β-strand	472-474	3	28
α-helix	475-476	2
α-helix	485-487	3
α-helix	489-490	2
α-helix	491-493	3
β-strand	497	1	37
β-strand	511-513	3	28
β-strand	514	1	37
β-strand	519-520	2	38
α-helix	527-535	9
α-helix	538	1
β-strand	539-540	2	39
β-strand	553-557	5	39
β-strand	560-565	6	39
α-helix	568-580	13
β-strand	589-593	5	39
β-strand	598-602	5	39
β-strand	608-614	7	38
β-strand	615-616	2	40
β-strand	619-620	2	40
α-helix	625-632	8
α-helix	637-642	6
β-strand	646-650	5	38
α-helix	653-656	4
β-strand	659-660	2	38
β-strand	672-673	2	38
α-helix	677-680	4
α-helix	685-687	3
α-helix	691-693	3
β-strand	694	1	41
α-helix	696-706	11
β-strand	709	1	42
β-strand	711	1	43
β-strand	725-728	4	43
β-strand	732	1	44
β-strand	736-737	2	45
α-helix	739-743	5
β-strand	753-759	7	46
β-strand	771-774	4	46
β-strand	785-795	11	43
β-strand	797	1	47
β-strand	803	1	47
β-strand	805	1	48
β-strand	811	1	49
β-strand	817	1	49
α-helix	818	1
α-helix	819-821	3
β-strand	829	1	50
α-helix	830-831	2
β-strand	832	1	51
β-strand	835-836	2	43
β-strand	841-843	3	50
β-strand	846-848	3	48
β-strand	866-868	3	48
β-strand	871-872	2	50
β-strand	879-888	10	43
β-strand	894-904	11	43
β-strand	911-913	3	52
β-strand	920-921	2	52
β-strand	922-926	5	46
α-helix	928-930	3
β-strand	933	1	53
β-strand	942-944	3	46
α-helix	946-948	3
β-strand	954	1	41
α-helix	955-970	16
β-strand	974-975	2	45
α-helix	984-993	10
β-strand	1001-1002	2	46
α-helix	1004	1
β-strand	1005	1	53
α-helix	1006	1
β-strand	1012	1	53
α-helix	1013	1
β-strand	1017-1024	8	46
β-strand	1025-1026	2	52
β-strand	1027	1	42
α-helix	1031-1033	3
β-strand	1036-1038	3	8
β-strand	1043-1044	2	54
β-strand	1049-1050	2	54
α-helix	1058-1059	2
β-strand	1060-1062	3	7
α-helix	1064-1073	10
α-helix	1076-1080	5
α-helix	1081-1085	5
β-strand	1090-1095	6	55
β-strand	1101-1102	2	55
β-strand	1103	1	56
β-strand	1106	1	56
β-strand	1116-1121	6	55
α-helix	1123-1134	12
β-strand	1140-1145	6	2

Chain C: 12 helices, 20 β-strands

Element	Residues	Length	Sheet
β-strand	4-7	4	57
β-strand	12-13	2	57
α-helix	36-39	4
β-strand	41-47	7	57
β-strand	51-57	7	57
α-helix	61-73	13
β-strand	77-88	12	58
α-helix	94-103	10
β-strand	106-107	2	59
α-helix	115-117	3
α-helix	122-125	4
β-strand	127	1	60
β-strand	131-139	9	58
β-strand	141-142	2	61
β-strand	157-158	2	61
β-strand	161-163	3	62
α-helix	164-166	3
β-strand	168-170	3	58
α-helix	175-178	4
β-strand	185-186	2	59
β-strand	192-195	4	62
β-strand	201-211	11	58
α-helix	217-219	3
β-strand	222-235	14	57
α-helix	242-248	7
β-strand	256-258	3	63
β-strand	265-267	3	63
α-helix	279-281	3
β-strand	289-304	16	57
α-helix	310-330	21
α-helix	332-333	2
β-strand	334	1	64

Chain D: 10 helices, 2 β-strands

Element	Residues	Length	Sheet
β-strand	3-5	3	25
β-strand	10	1	25
α-helix	15-26	12
α-helix	30-34	5
α-helix	56-67	12
α-helix	69-70	2
α-helix	100-104	5
α-helix	107-110	4
α-helix	120-123	4
α-helix	131-137	7
α-helix	141-144	4
α-helix	152-157	6

Chain E: 11 helices, 12 β-strands

Element	Residues	Length	Sheet
α-helix	3-27	25
α-helix	32-35	4
α-helix	39-46	8
β-strand	47	1	65
α-helix	52	1
β-strand	53	1	65
α-helix	54	1
β-strand	60-62	3	66
α-helix	66-71	6
β-strand	78-82	5	66
β-strand	87-88	2	67
α-helix	90-103	14
β-strand	107-112	6	66
β-strand	115-116	2	67
α-helix	120-123	4
β-strand	131-136	6	66
α-helix	144-146	3
β-strand	152-155	4	68
α-helix	158-167	10
β-strand	177-178	2	68
α-helix	183-188	6
β-strand	195-202	8	68
β-strand	206-214	9	68

Chain F: 5 helices, 5 β-strands

Element	Residues	Length	Sheet
α-helix	72	1
β-strand	73	1	25
α-helix	74-75	2
β-strand	84	1	69
α-helix	85-86	2
α-helix	87-102	16
α-helix	117-126	10
β-strand	133-137	5	25
β-strand	143-147	5	25
β-strand	152	1	69

Chain G: 5 helices, 12 β-strands

Element	Residues	Length	Sheet
β-strand	3-13	11	25
α-helix	15-18	4
α-helix	22-33	12
α-helix	37	1
β-strand	38-39	2	1
β-strand	43-44	2	1
β-strand	45-54	10	25
α-helix	55-56	2
β-strand	57-58	2	25
β-strand	66-76	11	25
β-strand	85	1	70
β-strand	88	1	71
β-strand	91	1	72
β-strand	98	1	72
β-strand	145	1	71
β-strand	148	1	70
α-helix	163-172	10

Chain H: 1 helix, 9 β-strands

Element	Residues	Length	Sheet
β-strand	4-16	13	12
β-strand	23-30	8	12
β-strand	37-43	7	12
β-strand	54-60	7	12
α-helix	81-83	3
β-strand	95-98	4	12
β-strand	100-108	9	12
β-strand	111-118	8	12
β-strand	121-127	7	12
β-strand	141-145	5	12

9 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
DNA-directed RNA polymerase III subunit RPC1	A	protein	1460	Saccharomyces cerevisiae S288C	P04051 (AlphaFold model)
DNA-directed RNA polymerase III subunit RPC2	B	protein	1149	Saccharomyces cerevisiae S288C	P22276 (AlphaFold model)
DNA-directed RNA polymerases I and III subunit RPAC1	C	protein	335	Saccharomyces cerevisiae S288C	P07703 (AlphaFold model)
DNA-directed RNA polymerase III subunit RPC9	D	protein	161	Saccharomyces cerevisiae S288C	P47076 (AlphaFold model)
DNA-directed RNA polymerases I, II, and III subunit RPABC1	E	protein	215	Saccharomyces cerevisiae S288C	P20434
DNA-directed RNA polymerases I, II, and III subunit RPABC2	F	protein	155	Saccharomyces cerevisiae S288C	P20435
DNA-directed RNA polymerase III subunit RPC8	G	protein	212	Saccharomyces cerevisiae S288C	P35718
DNA-directed RNA polymerases I, II, and III subunit RPABC3	H	protein	146	Saccharomyces cerevisiae S288C	P20436
DNA-directed RNA polymerase III subunit RPC10	I	protein	110	Saccharomyces cerevisiae S288C	Q04307
DNA-directed RNA polymerases I, II, and III subunit RPABC5	J	protein	70	Saccharomyces cerevisiae S288C	P22139
DNA-directed RNA polymerases I and III subunit RPAC2	K	protein	142	Saccharomyces cerevisiae S288C	P28000
DNA-directed RNA polymerases I, II, and III subunit RPABC4	L	protein	70	Saccharomyces cerevisiae S288C	P40422

7 more molecules are not listed.

Sequence of entity 1 (A), FASTA

>7Z0H_1 DNA-directed RNA polymerase III subunit RPC1 (chains A)
MKEVVVSETPKRIKGLEFSALSAADIVAQSEVEVSTRDLFDLEKDRAPKANGALDPKMGV
SSSSLECATCHGNLASCHGHFGHLKLALPVFHIGYFKATIQILQGICKNCSAILLSETDK
RQFLHELRRPGVDNLRRMGILKKILDQCKKQRRCLHCGALNGVVKKAAAGAGSAALKIIH
DTFRWVGKKSAPEKDIWVGEWKEVLAHNPELERYVKRCMDDLNPLKTLNLFKQIKSADCE
LLGIDATVPSGRPETYIWRYLPAPPVCIRPSVMMQDSPASNEDDLTVKLTEIVWTSSLIK
AGLDKGISINNMMEHWDYLQLTVAMYINSDSVNPAMLPGSSNGGGKVKPIRGFCQRLKGK
QGRFRGNLSGKRVDFSGRTVISPDPNLSIDEVAVPDRVAKVLTYPEKVTRYNRHKLQELI
VNGPNVHPGANYLLKRNEDARRNLRYGDRMKLAKNLQIGDVVERHLEDGDVVLFNRQPSL
HRLSILSHYAKIRPWRTFRLNECVCTPYNADFDGDEMNLHVPQTEEARAEAINLMGVKNN
LLTPKSGEPIIAATQDFITGSYLISHKDSFYDRATLTQLLSMMSDGIEHFDIPPPAIMKP
YYLWTGKQVFSLLIKPNHNSPVVINLDAKNKVFVPPKSKSLPNEMSQNDGFVIIRGSQIL
SGVMDKSVLGDGKKHSVFYTILRDYGPQEAANAMNRMAKLCARFLGNRGFSIGINDVTPA
DDLKQKKEELVEIAYHKCDELITLFNKGELETQPGCNEEQTLEAKIGGLLSKVREEVGDV
CINELDNWNAPLIMATCGSKGSTLNVSQMVAVVGQQIISGNRVPDGFQDRSLPHFPKNSK
TPQSKGFVRNSFFSGLSPPEFLFHAISGREGLVDTAVKTAETGYMSRRLMKSLEDLSCQY
DNTVRTSANGIVQFTYGGDGLDPLEMEGNAQPVNFNRSWDHAYNITFNNQDKGLLPYAIM
ETANEILGPLEERLVRYDNSGCLVKREDLNKAEYVDQYDAERDFYHSLREYINGKATALA
NLRKSRGMLGLLEPPAKELQGIDPDETVPDNVKTSVSQLYRISEKSVRKFLEIALFKYRK
ARLEPGTAIGAIGAQSIGEPGTQMTLKTFHFAGVASMNVTLGVPRIKEIINASKVISTPI
INAVLVNDNDERAARVVKGRVEKTLLSDVAFYVQDVYKDNLSFIQVRIDLGTIDKLQLEL
TIEDIAVAITRASKLKIQASDVNIIGKDRIAINVFPEGYKAKSISTSAKEPSENDVFYRM
QQLRRALPDVVVKGLPDISRAVINIRDDGKRELLVEGYGLRDVMCTDGVIGSRTTTNHVL
EVFSVLGIEAARYSIIREINYTMSNHGMSVDPRHIQLLGDVMTYKGEVLGITRFGLSKMR
DSVLQLASFEKTTDHLFDAAFYMKKDAVEGVSECIILGQTMSIGTGSFKVVKGTNISEKD
LVPKRCLFESLSNEAALKAN

Sequence of entity 2 (B), FASTA

>7Z0H_2 DNA-directed RNA polymerase III subunit RPC2 (chains B)
MVAATKRRKTHIHKHVKDEAFDDLLKPVYKGKKLTDEINTAQDKWHLLPAFLKVKGLVKQ
HLDSFNYFVDTDLKKIIKANQLILSDVDPEFYLKYVDIRVGKKSSSSTKDYLTPPHECRL
RDMTYSAPIYVDIEYTRGRNIIMHKDVEIGRMPIMLRSNKCILYDADESKMAKLNECPLD
PGGYFIVNGTEKVILVQEQLSKNRIIVEADEKKGIVQASVTSSTHERKSKTYVITKNGKI
YLKHNSIAEEIPIAIVLKACGILSDLEIMQLVCGNDSSYQDIFAVNLEESSKLDIYTQQQ
ALEYIGAKVKTMRRQKLTILQEGIEAIATTVIAHLTVEALDFREKALYIAMMTRRVVMAM
YNPKMIDDRDYVGNKRLELAGQLISLLFEDLFKKFNNDFKLSIDKVLKKPNRAMEYDALL
SINVHSNNITSGLNRAISTGNWSLKRFKMERAGVTHVLSRLSYISALGMMTRISSQFEKS
RKVSGPRALQPSQFGMLCTADTPEGEACGLVKNLALMTHITTDDEEEPIKKLCYVLGVED
ITLIDSASLHLNYGVYLNGTLIGSIRFPTKFVTQFRHLRRTGKVSEFISIYSNSHQMAVH
IATDGGRICRPLIIVSDGQSRVKDIHLRKLLDGELDFDDFLKLGLVEYLDVNEENDSYIA
LYEKDIVPSMTHLEIEPFTILGAVAGLIPYPHHNQSPRNTYQCAMGKQAIGAIAYNQFKR
IDTLLYLMTYPQQPMVKTKTIELIDYDKLPAGQNATVAVMSYSGYDIEDALVLNKSSIDR
GFGRCETRRKTTTVLKRYANHTQDIIGGMRVDENGDPIWQHQSLGPDGLGEVGMKVQSGQ
IYINKSVPTNSADAPNPNNVNVQTQYREAPVIYRGPEPSHIDQVMMSVSDNDQALIKVLL
RQNRRPELGDKFSSRHGQKGVCGIIVKQEDMPFNDQGIVPDIIMNPHGFPSRMTVGKMIE
LISGKAGVLNGTLEYGTCFGGSKLEDMSKILVDQGFNYSGKDMLYSGITGECLQAYIFFG
PIYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCVIAYGASQLLL
ERLMISSDAFEVDVCDKCGLMGYSGWCTTCKSAENIIKMTIPYAAKLLFQELLSMNIAPR
LRLEDIFQQ

Sequence of entity 3 (C), FASTA

>7Z0H_3 DNA-directed RNA polymerases I and III subunit RPAC1 (chains C)
MSNIVGIEYNRVTNTTSTDFPGFSKDAENEWNVEKFKKDFEVNISSLDAREANFDLINID
TSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHRIGLVPLKVDPDMLTWVDSNL
PDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELYNNAHVYARDLKFEPQGRQSTTFA
DCPVVPADPDILLAKLRPGQEISLKAHCILGIGGDHAKFSPVSTASYRLLPQINILQPIK
GESARRFQKCFPPGVIGIDEGSDEAYVKDARKDTVSREVLRYEEFADKVKLGRVRNHFIF
NVESAGAMTPEEIFFKSVRILKNKAEYLKNCPITQ

Sequence of entity 4 (D), FASTA

>7Z0H_4 DNA-directed RNA polymerase III subunit RPC9 (chains D)
MKVLEERNAFLSDYEVLKFLTDLEKKHLWDQKSLAALKKSRSKGKQNRPYNHPELQGITR
NVVNYLSINKNFINQEDEGEERESSGAKDAEKSGISKMSDESFAELMTKLNSFKLFKAEK
LQIVNQLPANMVHLYSIVEECDARFDEKTIEEMLEIISGYA

Sequence of entity 5 (E), FASTA

>7Z0H_5 DNA-directed RNA polymerases I, II, and III subunit RPABC1 (chains E)
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSF
QANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSA
MKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQR
ADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM

Sequence of entity 6 (F), FASTA

>7Z0H_6 DNA-directed RNA polymerases I, II, and III subunit RPABC2 (chains F)
MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVTGGNGPEDFQQ
HEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRI
AMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL

Sequence of entity 7 (G), FASTA

>7Z0H_7 DNA-directed RNA polymerase III subunit RPC8 (chains G)
MFILSKIADLVRIPPDQFHRDTISAITHQLNNKFANKIIPNVGLCITIYDLLTVEEGQLK
PGDGSSYINVTFRAVVFKPFLGEIVTGWISKCTAEGIKVSLLGIFDDIFIPQNMLFEGCY
YTPEESAWIWPMDEETKLYFDVNEKIRFRIEREVFVDVKPKSPKERELEERAQLENEIEG
KNEETPQNEKPPAYALLGSCQTDGMGLVSWWE

Sequence of entity 8 (H), FASTA

>7Z0H_8 DNA-directed RNA polymerases I, II, and III subunit RPABC3 (chains H)
MSNTLFDDIFQVSEVDPGRYNKVCRIEAASTTQDQCKLTLDINVELFPVAAQDSLTVTIA
SSLNLEDTPANDSSATRSWRPPQAGDRSLADDYDYVMYGTAYKFEEVSKDLIAVYYSFGG
LLMRLEGNYRNLNNLKQENAYLLIRR

Sequence of entity 9 (I), FASTA

>7Z0H_9 DNA-directed RNA polymerase III subunit RPC10 (chains I)
MLSFCPSCNNMLLITSGDSGVYTLACRSCPYEFPIEGIEIYDRKKLPRKEVDDVLGGGWD
NVDQTKTQCPNYDTCGGESAYFFQLQIRSADEPMTTFYKCVNCGHRWKEN

Sequence of entity 10 (J), FASTA

>7Z0H_10 DNA-directed RNA polymerases I, II, and III subunit RPABC5 (chains J)
MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKF
LRYNPLEKRD

Sequence of entity 11 (K), FASTA

>7Z0H_11 DNA-directed RNA polymerases I and III subunit RPAC2 (chains K)
MTEDIEQKKTATEVTPQEPKHIQEEEEQDVDMTGDEEQEEEPDREKIKLLTQATSEDGTS
ASFQIVEEDHTLGNALRYVIMKNPDVEFCGYSIPHPSENLLNIRIQTYGETTAVDALQKG
LKDLMDLCDVVESKFTEKIKSM

Sequence of entity 12 (L), FASTA

>7Z0H_12 DNA-directed RNA polymerases I, II, and III subunit RPABC4 (chains L)
XXXXXXXXXXXXXXXXXXXXXXXXXXLKYICAECSSKLSLSRTDAVRCKDCGHRILLKAR
TKRLVQFEAR

Ligands and cofactors

ID	Name	Formula	Copies
ZN	Zinc ion	Zn	7
MG	Magnesium ion	Mg	2

Primary citation

Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration. Nguyen, P.Q., Huecas, S., Asif-Laidin, A. et al. Nat Commun (2023) 14:1729-1729. DOI 10.1038/s41467-023-37109-4 · PubMed

Other PDB entries of the same protein (UniProt P04051 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7Z1O 2.7 Å, Structure of yeast RNA Polymerase III PTC + NTPs
7Z31 2.76 Å, Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11,…
7Z1L 2.8 Å, Structure of yeast RNA Polymerase III Pre-Termination Complex (PTC)
7Z30 2.9 Å, Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.9 A (focus subunit C11…
7Z2Z 3.07 Å, Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A
8BWS 3.2 Å, Structure of yeast RNA Polymerase III elongation complex at 3.3 A
6TUT 3.25 Å, Cryo-EM structure of the RNA Polymerase III-Maf1 complex
6EU3 3.3 Å, Apo RNA Polymerase III - closed conformation (cPOL3)
6EU1 3.4 Å, RNA Polymerase III - open DNA complex (OC-POL3).
6EU2 3.4 Å, Apo RNA Polymerase III - open conformation (oPOL3)
7Z1M 3.4 Å, Structure of yeast RNA Polymerase III Elongation Complex (EC)
6F40 3.7 Å, RNA Polymerase III open complex

Browse structure collections

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