6FDD: HHD2 Domain of Whirlin

Crystal Structure of the HHD2 Domain of Whirlin. Determined by X-ray diffraction at 1.75 Å resolution. Released 8 Aug 2018.

Method: X-ray diffraction
Resolution: 1.75 Å
Organism: Mus musculus
Chains: 6
Atoms: 4,335
Mol. weight: 60.17 kDa
Released: 8 Aug 2018

Explore 6FDD in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6FDD contains 42 α-helices and 0 β-strands across 6 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chains A, D and E: 7 helices, 0 β-strands

Element	Residues	Length
α-helix	425-434	10
α-helix	437-451	15
α-helix	457-467	11
α-helix	471-474	4
α-helix	476-481	6
α-helix	486-488	3
α-helix	489-495	7

Chain B: 7 helices, 0 β-strands

Element	Residues	Length
α-helix	425-432	8
α-helix	437-451	15
α-helix	457-467	11
α-helix	471-474	4
α-helix	476-481	6
α-helix	486-488	3
α-helix	489-495	7

Chain C: 7 helices, 0 β-strands

Element	Residues	Length
α-helix	424-434	11
α-helix	437-451	15
α-helix	457-467	11
α-helix	471-474	4
α-helix	476-481	6
α-helix	486-488	3
α-helix	489-495	7

Chain F: 7 helices, 0 β-strands

Element	Residues	Length
α-helix	426-431	6
α-helix	437-451	15
α-helix	457-467	11
α-helix	471-474	4
α-helix	476-481	6
α-helix	486-488	3
α-helix	489-495	7

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Whirlin	A, B, C, D, E, F	protein	85	Mus musculus	Q80VW5 (AlphaFold model)

Sequence of entity 1 (A, B, C, D, E, F), FASTA

>6FDD_1 Whirlin (chains A, B, C, D, E, F)
GAMGSGNQTRALLDDQARHLLTEQERATMMYYLAQYRGGTISVEAMVMALFELLNTHAKF
SLLSEVRSIISPQDLDRFDHLVLRR

Primary citation

Structural plasticity of the HHD2 domain of whirlin. Delhommel, F., Cordier, F., Saul, F. et al. FEBS J (2018) 285:3738-3752. DOI 10.1111/febs.14614 · PubMed

Other PDB entries of the same protein (UniProt Q80VW5 (AlphaFold model), which also has an AlphaFold model), best resolution first:

6Y9Q 1.31 Å, Crystal structure of Whirlin PDZ3_C-ter in complex with Taperin internal PDZ binding…
6Y9O 1.63 Å, Crystal structure of Whirlin PDZ3_C-ter in complex with CASK internal PDZ binding motif…
6Y38 1.7 Å, Crystal structure of Whirlin PDZ3 in complex with Myosin 15a C-terminal PDZ binding…
6FDE 1.85 Å, Crystal Structure of the HHD2 Domain of Whirlin : 3-helix conformation
6Y9N 1.93 Å, Crystal structure of Whirlin PDZ3_C-ter in complex with Myosin 15a C-terminal PDZ…
6Y9P 3.17 Å, Crystal structure of Whirlin PDZ3_C-ter in complex with Harmonin a1 C-terminal PDZ…

Browse structure collections

About this viewer

MolViewer shows 6FDD directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.