6JJY: KIBRA and beta-Dystroglycan

Crystal Structure of KIBRA and beta-Dystroglycan. Determined by X-ray diffraction at 2.3 Å resolution. Released 25 Sept 2019.

Method: X-ray diffraction
Resolution: 2.3 Å
Organisms: Mus musculus, Homo sapiens
Chains: 2
Atoms: 1,289
Mol. weight: 18.53 kDa
Released: 25 Sept 2019

Explore 6JJY in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6JJY contains 6 α-helices and 6 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 5 helices, 6 β-strands

Element	Residues	Length	Sheet
α-helix	6-9	4
β-strand	12-16	5	1
β-strand	22-26	5	1
β-strand	31-33	3	1
α-helix	39-41	3
α-helix	47-49	3
α-helix	54-56	3
β-strand	59-64	6	2
β-strand	68-73	6	2
β-strand	78-80	3	2
α-helix	84-128	45

Chain U: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	885-892	8

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Protein KIBRA	A	protein	134	Mus musculus	Q5SXA9 (AlphaFold model)
Peptide from Dystroglycan	U	protein	21	Homo sapiens	Q14118 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>6JJY_1 Protein KIBRA (chains A)
GPGSEFELPLPEGWEEARDFDGKVYYIDHRNRTTSWIDPRDRYTKPLTFADCISDELPLG
WEEAYDPQVGDYFIDHNTKTTQIEDPRVQWRREQEHMLKDYLVVAQEALSAQKEIYQVKQ
QRLELAQQEYQQLH

Sequence of entity 2 (U), FASTA

>6JJY_2 Peptide from Dystroglycan (chains U)
GPGSRPKNMTPYRSPPPYVPP

Primary citation

Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity. Lin, Z., Yang, Z., Xie, R. et al. Elife (2019) 8. DOI 10.7554/eLife.49439 · PubMed

Other PDB entries of the same protein (UniProt Q5SXA9 (AlphaFold model), which also has an AlphaFold model), best resolution first:

6JJX 2.0 Å, Crystal Structure of KIBRA and Angiomotin complex
6JJW 2.4 Å, Crystal Structure of KIBRA and PTPN14 complex
6J68 2.5 Å, Structure of KIBRA and LATS1 Complex
6J69 2.75 Å, Structure of KIBRA and Dendrin Complex

Browse structure collections

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