6P5N: Mammalian 80S ribosome

Name: PDB 6P5N: Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis Virus IRES and eRF1
Published: 2019-09-25
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: ribosome

Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis Virus IRES and eRF1. Determined by electron microscopy at 3.2 Å resolution. Released 25 Sept 2019.

Method: Electron microscopy
Resolution: 3.2 Å
Organisms: Oryctolagus cuniculus, Homo sapiens, Israeli acute paralysis virus
Chains: 82
Atoms: 219,295
Mol. weight: 3460.27 kDa
Released: 25 Sept 2019

Explore 6P5N in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6P5N contains 499 α-helices and 585 β-strands across 77 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain a: 3 helices, 6 β-strands

Element	Residues	Length	Sheet
β-strand	47	1	151
β-strand	50	1	107
α-helix	52-60	9
β-strand	68	1	152
α-helix	73-76	4
β-strand	79	1	151
α-helix	81-94	14
β-strand	98-102	5	152
β-strand	107-110	4	152

Chain Aa: 7 helices, 9 β-strands

Element	Residues	Length	Sheet
α-helix	8-10	3
β-strand	29	1	22
β-strand	31	1	22
α-helix	42-48	7
β-strand	72-73	2	23
α-helix	75-80	6
α-helix	84-92	9
α-helix	97	1
β-strand	98	1	106
α-helix	99	1
β-strand	100-102	3	24
β-strand	110-111	2	23
β-strand	123-126	4	24
β-strand	128-129	2	23
α-helix	131-139	9
β-strand	143-146	4	24

Chain AA: 8 helices, 19 β-strands

Element	Residues	Length	Sheet
α-helix	6-10	5
β-strand	18	1	33
α-helix	30-32	3
α-helix	34-37	4
β-strand	40-49	10	34
β-strand	58-63	6	34
β-strand	72-77	6	34
α-helix	78	1
β-strand	79	1	35
β-strand	83	1	36
β-strand	87-91	5	34
β-strand	101-103	3	34
β-strand	113-114	2	34
β-strand	116	1	37
β-strand	126	1	37
β-strand	136-138	3	38
β-strand	146-149	4	38
β-strand	155-158	4	38
β-strand	163-166	4	34
α-helix	168	1
β-strand	169	1	35
α-helix	182-189	8
β-strand	193	1	33
α-helix	201-203	3
β-strand	224-225	2	39
α-helix	229-230	2
β-strand	237-238	2	39

Chain Ab: 8 helices, 0 β-strands

Element	Residues	Length
α-helix	12-18	7
α-helix	22-24	3
α-helix	37-48	12
α-helix	51-53	3
α-helix	55-64	10
α-helix	66-75	10
α-helix	91-99	9
α-helix	108-114	7

Chain AB: 17 helices, 21 β-strands

Element	Residues	Length	Sheet
α-helix	9-10	2
α-helix	32-34	3
α-helix	40-41	2
β-strand	42-43	2	44
β-strand	45-59	15	45
β-strand	71-80	10	45
α-helix	82-83	2
β-strand	84-95	12	46
β-strand	98-106	9	46
α-helix	112-115	4
α-helix	116-118	3
α-helix	134-137	4
α-helix	143-146	4
α-helix	148-151	4
β-strand	159-165	7	46
α-helix	178-179	2
β-strand	180-184	5	46
β-strand	185-186	2	44
α-helix	190-199	10
β-strand	204-205	2	46
α-helix	207-210	4
β-strand	216-222	7	45
β-strand	228-229	2	47
α-helix	231-234	4
α-helix	237-240	4
α-helix	262-263	2
β-strand	270-271	2	47
β-strand	276-283	8	45
β-strand	286-287	2	45
β-strand	292-294	3	48
β-strand	297-299	3	48
β-strand	320	1	49
β-strand	324	1	49
β-strand	330-334	5	45
β-strand	344-348	5	45
α-helix	361-363	3
β-strand	365-368	4	45
α-helix	382-389	8

Chain Ac: 4 helices, 4 β-strands

Element	Residues	Length	Sheet
α-helix	11-24	14
β-strand	26-29	4	50
α-helix	32-39	8
β-strand	45-48	4	50
α-helix	54-67	14
β-strand	70-73	4	50
α-helix	78-84	7
β-strand	93-98	6	50

Chain AC: 20 helices, 12 β-strands

Element	Residues	Length	Sheet
β-strand	7-11	5	53
β-strand	17-23	7	53
α-helix	26-29	4
α-helix	34-44	11
α-helix	45-47	3
β-strand	65-66	2	54
β-strand	77-78	2	54
α-helix	79-81	3
α-helix	100-101	2
α-helix	104-106	3
α-helix	117-132	16
α-helix	134-138	5
β-strand	154	1	53
α-helix	164-173	10
α-helix	177-186	10
β-strand	188-189	2	55
α-helix	193-195	3
β-strand	201-202	2	55
β-strand	208-211	4	56
α-helix	217-221	5
β-strand	228-231	4	56
β-strand	234	1	56
β-strand	250-252	3	56
β-strand	253	1	53
α-helix	254-258	5
α-helix	260-263	4
α-helix	278-282	5
α-helix	289-294	6
α-helix	296-300	5
α-helix	303-305	3
α-helix	322-328	7
α-helix	331-362	32

Chain Ad: 4 helices, 7 β-strands

Element	Residues	Length	Sheet
β-strand	22-28	7	57
α-helix	29-33	5
α-helix	38-40	3
α-helix	42-56	15
β-strand	62-64	3	57
α-helix	66-72	7
β-strand	74	1	58
β-strand	76	1	58
β-strand	83-92	10	57
β-strand	102-108	7	57
β-strand	120-122	3	57

69 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
28S rRNA	5	RNA	3594	Oryctolagus cuniculus
5S rRNA	7	RNA	119	Oryctolagus cuniculus
5.8S rRNA	8	RNA	156	Oryctolagus cuniculus
uL2	AA	protein	257	Oryctolagus cuniculus	G1TT27 (AlphaFold model)
uL3	AB	protein	402	Oryctolagus cuniculus	G1TL06 (AlphaFold model)
uL4	AC	protein	392	Oryctolagus cuniculus	G1SVW5 (AlphaFold model)
uL18	AD	protein	297	Oryctolagus cuniculus	P19949 (AlphaFold model)
eL6	AE	protein	291	Oryctolagus cuniculus	G1SKF7
L30	AF	protein	249	Oryctolagus cuniculus	G1SV32
eL8	AG	protein	242	Oryctolagus cuniculus	G1STW0
uL6	AH	protein	192	Oryctolagus cuniculus	G1SWI6
uL16	AI	protein	214	Oryctolagus cuniculus	B7NZQ2

70 more molecules are not listed.

Sequence of entity 1 (5), FASTA

>6P5N_1 28S rRNA (chains 5)
CGCGACCUCAGAUCAGACGUGGCGACCCGCUGAAUUUAAGCAUAUUAGUCAGCGGAGGAA
AAGAAACUAACCAGGAUUCCCUCAGUAACGGCGAGUGAACAGGGAAGAGCCCAGCGCCGA
AUCCCCGCCCCGCGGCGGGGCGCGGGAAAUGUGGCGUACGGAAGACCCACUCCCCGGCGC
CGGGGGGCCCAAGUCCUUCUGAUCGAGGCCCAGCCCGUGGACGGUGUGAGGCCGGUAGCG
GCCCCCGGCGCGCCGGGCCCGGGUCUUCCCGGAGUCGGGUUGCUUGGGAAUGCAGCCCAA
AGCGGGUGGUAAACUCCAUCUAAGGCUAAAUACCGGCACGAGACCGAUAGUCAACAAGUA
CCGUAAGGGAAAGUUGAAAAGAACUUUGAAGAGAGAGUUCAAGAGGGCGUGAAACCGUUA
AGAGGUAAACGGGUGGGGUCCGCGCAGUCCGCCCGGAGGAUUCAACCCGGCGGCGGGUCC
GGCCGUGCCGGCGGGGCGGAUCUCCCGCUCCCGUCGGCGGGGGACCGCCCCCCGGCCGGC
GACCGGCCGCCGCCGGGCGCAUUUCCACCGCGGCGGUGCGCCGCGACCGGCUCCGGGACG
GCUGGGAAGGCCCGGCGGGGAAGGUGGCCCGGGGGCCCCGGGUGUUACAGCCCACCCGGC
AGCAGCAGCUCGCCGAAUCCCGGGGCCGAGGGAGCGAGACCUGUGUCGCCGCGCUCUCCC
CCCUGGGGGGGCCGGGCCACCCCUCCCACGGCGCGACCGCUGGGGCGGACUGUCCAGUGC
GCCCCGGGCGGGUCGCGCCGUCGGGCCCGGGGGGCCACGCGUCCCCCGCGAGCGCACGGG
GUCGGCGGCGAUGUCGGCUACCCACCCGACCCGUCUUGAAACACGGACCAAGGAGUCUAA
CACGUGCGCGAGUCGGGGGCUACGAAAGCCGCCGUGGCGCAAUGAAGGUGAAGGCCGGCG
CCGCCGGCCGAGGUGGGAUCCCGAGGCCUUCCAGUCCGCCGAGGGCGCACCACCGGCCCG
UCUCGCCCGCCGCGCCGGGGAGGUGGAGCACGAGCGCACGUGUUAGGACCCGAAAGAUGG
UGAACUAUGCCUGGGCAGGGCGAAGCCAGAGGAAACUCUGGUGGAGGUCCGUAGCGGUCC
UGACGUGCGAAUCGGUCGUCCGACCUGGGUAUAGGGGCGAAAGACUAAUCGAACCAUCUA
GUAGCUGGUUCCCUCCAAAGUUUCCCUCAGGAUAGCUGGCGCUCUCCGCAGUUUUAUCCG
GUAAAGCGAAUGAUUAGAGGUCUUGGGGCCGAAACGAUCUCAACCUAUUCUCAAACUUUA
AAUGGGUAAGAAGCCCGGCUCGCUGGUGUGGAGCCGGGCGUGGAAUGCGAGUGCCUAGUG
GGCCACUUUUGGUAAGCAGAACUGGCGCUGCGGGAUGAACCGAACGCCGGGUUAAGGCGC
CCGAUGCCGACGCUCAUCAGACCCCAGAAAAGGUGUUGGUUGAUAUAGACAGCAGGAUGG
UGGCCAUGGAAGUCGGAAUCCGCUAAGGAGUGUGUAACAACUCACCUGCCGAAUCAACUA
GCCCUGAAAAUGGAUGGCGCUGGAGCGUCGGGCCCAUACCCGGCCGUCGCUGGCAGUCGG
CAGAGCGAGAAAGAGAGUGGCGCGGACGCUACGCCGCGACGAGUAGGAGGGCCGCUGCGG
UGAGCCUUGAAGCCUAGGGCGCGGGCCCGGGUGGAGCCGCCGCAGGUGCAGAUCUUGGUG
GUAGUAGCAAAUAUUCAAACGAGAACUUUGAAGGCCGAAGUGGAGAAGGGUUCCAUGUGA
ACAGCAGUUGAACAUGGGUCAGUCGGUCCUGAGAGAUGGGCGAGCGCCGUUCCGAAGGGA
CGGGCGAUGGCCUCCGUUGCCCUCAGCCGAUCGAAAGGGAGUCGGGUUCAGAUCCCCGAA
UCCGGAGUGGCGGAGAUGGGCGCCGCGAGGCGUCCAGUGCGGUAACGCGACCGAUCCCGG
AGAAGCCGGCGGGAGCCCCGGGGAGAGUUCUCUUUUCUUUGUGAAGGGCAGGGCGCCCUG
GAAUGGGUUCGCCCCGAGAGAGGGGCCCGUGCCUUGGAAAGCGUCGCGGUUCCGGCGGCG
UCCGGUGAGCUCUCGCUGGCCCUUGAAAAUCCGGGGGAGAGGGUGUAAAUCUCGCGCCGG
GCCGUACCCAUAUCCGCAGCAGGUCUCCAAGGUGAACAGCCUCUGGCAUGUUGGAACAAU
GUAGGUAAGGGAAGUCGGCAAGCCGGAUCCGUAACUUCGGGAUAAGGAUUGGCUCUAAGG
GCUGGCAGCCGACUUAGAACUGGUGCGGACCAGGGGAAUCCGACUGUUUAAUUAAAACAA
AGCAUCGCGAAGGCCCGCGGCGGGUGUUGACGCGAUGUGAUUUCUGCCCAGUGCUCUGAA
UGUCAAAGUGAAGAAAUUCAAUGAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCU
UAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUGAACGAGAUU
CCCACUGUCCCUACCUACUAUCCAGCGAAACCACAGCCAAGGGAACGGGCUUGGCGGAAU
CAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUCUGGCACGGUGAAGAGACAUGA
GAGGUGUAGAAUAAGUGGGAGGCCCGGGCCGCCGGUGAAAUACCACUACUCUGAUCGUUU
UUUCACUGACCCGGUGAGGCGGGGGGGCGAGCCGGGCUCUCGCUUCUGGCGCCAAGCGCC
CGGCCGGCCGGGCGCGACCCGCUCCGGGGACAGUGCCAGGUGGGGAGUUUGACUGGGGCG
GUACACCUGUCAAACGGUAACGCAGGUGUCCUAAGGCGAGCUCAGGGAGGACAGAAACCU
CCCGUGGAGCAGAAGGGCAAAAGCUCGCUUGAUCUUGAUUUUCAGUACGAAUACAGACCG
UGAAAGCGGGGCCUCACGAUCCUUCUGACCUUUUGGGUUUUAAGCAGGAGGUGUCAGAAA
AGUUACCACAGGGAUAACUGGCUUGUGGCGGCCAAGCGUUCAUAGCGACGUCGCUUUUUG
AUCCUUCGAUGUCGGCUCUUCCUAUCAUUGUGAAGCAGAAUUCACCAAGCGUUGGAUUGU
UCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUAC
CCUACUGAUGAUGUGUUGUUGCCAUGGUAAUCCUGCUCAGUACGAGAGGAACCGCAGGUU
CAGACAUUUGGUGUAUGUGCUUGGCUGAGGAGCCAAUGGGGCGAAGCUACCAUCUGUGGG
AUUAUGACUGAACGCCUCUAAGUCAGAAUCCCGCCCAGGCGGAACGAUAGCGCCGGAGCC
UCGGUUGGCCUCGGAUAGCCGGUCCCCCGCCGGGGUCCGGUGCGGAGAGCCCUUCGUCCC
GGGAAACGGGGCGGCCGGAAAGGGGGCCGCCCUCUCGCCCGUCACGCACCGCACGUUCGU
GGGGAACCUGGCGCUAAACCAUUCGUAGACGACCUGCUUCUGGGUCGGGGUUUCGUACGU
AGCAGAGCAGCUGCUGCGAUCUAUUGAAAGUCAGCCCUCGACACAAGGGUUUGU

Sequence of entity 2 (7), FASTA

>6P5N_2 5S rRNA (chains 7)
GUCUACGGCCAUACCACCCUGAACGCGCCCGAUCUCGUCUGAUCUCGGAAGCUAAGCAGG
GUCGGGCCUGGUUAGUACUUGGAUGGGAGACCGCCUGGGAAUACCGGGUGCUGUAGGCU

Sequence of entity 3 (8), FASTA

>6P5N_3 5.8S rRNA (chains 8)
CGACUCUUAGCGGUGGAUCACUCGGCUCGUGCGUCGAUGAAGAACGCAGCUAGCUGCGAG
AAUUAAUGUGAAUUGCAGGACACAUUGAUCAUCGACACUUCGAACGCACUUGCGGCCCCG
GGUUCCUCCCGGGGCUACGCCUGUCUGAGCGUCGCU

Sequence of entity 4 (AA), FASTA

>6P5N_4 uL2 (chains AA)
MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAK
VVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKP
GDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPIL
KAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAA
RRTGRLRGTKTVQEKEN

Sequence of entity 5 (AB), FASTA

>6P5N_5 uL3 (chains AB)
SHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREVD
RPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYKN
WHKSKKKAFTKYCKKWQDDAGKRQLDKDFSSMKKYCQVIRVLAHTQMRLLPLRQKKAHLM
EIQVNGGTVAEKLDWARERLEQQVPVSQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKLP
RKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIKN
NASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRALE
KIDLKFIDTTSKFGHGRFQTVEEKKAFMGPLKKDRIAKEEGA

Sequence of entity 6 (AC), FASTA

>6P5N_6 uL4 (chains AC)
AAGRRGAWLSPLPAMACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRK
NNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTK
TWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKE
AVLLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCVIYNEDNGIVKAFRNIPG
ITLLNVTKLNILKLAPGGHVGRFCIWTESAFRKLDDLYGTWRKAASLKSNYNLPMHKMLN
TDLSRILKSPEIQRALRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARN
HKLRVERAAAALAAKSDPKEAPAKKKPVVGKK

Sequence of entity 7 (AD), FASTA

>6P5N_7 uL18 (chains AD)
KGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDI
ICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYE
GQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRF
PGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMY
KKAHAAIRENPVYEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES

Sequence of entity 8 (AE), FASTA

>6P5N_8 eL6 (chains AE)
MAGEKAPAAKPDATKKSPAKKADHARGKAKKKTLAEKKPKKGKPHCSRNPVLVRGIGRYS
RSAMYSRKALYKRKYAAPKSRIERKKKREKVLATVTKPVGGDKNGGTRVVKLRKMPRYYP
TEDVPRKLLSHGKKPFSQHVRKLRASITPGTILIILTGRHRGKRVVFLKQLSSGLLLVTG
PLSLNRVPLRRTHQKFVIATSTKIDISGVKIPKHLTDAYFKKKKLRKPRHQEGEIFDTEK
EKYEITEQRKVDQKAVDSQILPKIKAVPQLQGYLRSVFALTNGVYPHKLVF

Sequence of entity 9 (AF), FASTA

>6P5N_9 L30 (chains AF)
LFANNIREKKKVPAVPETLKKKRRNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHK
EYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFN
GTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNTLIARSL
GKYNIICMEDLIHEIYTVGKHFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQ
INRLIRRMN

Sequence of entity 10 (AG), FASTA

>6P5N_10 eL8 (chains AG)
KKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFT
QVLDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVT
TLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCILKGKARLCRLVHRKTCTTVAF
TQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATK
LG

Sequence of entity 11 (AH), FASTA

>6P5N_11 uL6 (chains AH)
MKTILSNQTVDIPENVDISLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKW
WGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGE
KYIRRVRMRPGVACSVSQAQKDELVLEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIY
VSEKGTVQQADE

Sequence of entity 12 (AI), FASTA

>6P5N_12 uL16 (chains AI)
MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL
SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG
KPQGTVARVHIGQVIMSIRTKLQNKEHVVEALRRAKFKFPGRQKIHISKKWGFTKFNADE
FEDMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS

Primary citation

The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Acosta-Reyes, F., Neupane, R., Frank, J. et al. EMBO J (2019) 38:e102226-e102226. DOI 10.15252/embj.2019102226 · PubMed

Other PDB entries of the same protein (UniProt G1TT27 (AlphaFold model), which also has an AlphaFold model), best resolution first:

11IQ 2.4 Å, Rabbit 80S with eEF2,eIF5A and SERBP1
8SCB 2.5 Å, Terminating ribosome with SRI-41315
9MR4 2.65 Å, NAC: Ribosome nascent chain complex(Oxa1L)
9RHU 2.65 Å, Rabbit 80S ribosome in complex with eRF1-AAQ, stalled at the Stop codon in mutated F2A…
8RJB 2.69 Å, Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in…
8VVQ 2.7 Å, Codon sampling state of elongation inhibitor-treated mammalian ribosomes obtained from…
8RJD 2.79 Å, Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in…
8B6C 2.79 Å, Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative…
6SGC 2.8 Å, Rabbit 80S ribosome stalled on a poly(A) tail
7UCK 2.8 Å, 80S translation initiation complex with ac4c(-1) mRNA and Harringtonine
9BDL 2.8 Å, 80S ribosome with angiogenin
9QQA 2.8 Å, Ternary complex of translating ribosome, NAC and NMT1

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